Retatrutide dosing and titration (ramp)

[ciaka_express]

Ive been looking through research docs, forums, etc, and wanted to know from those with 1st hand experience with reta, what they started at, how quickly they titrated up, what levels they titrated to, how long they stayed there, etc.
Im considering for cut.
What i read so far is that in studies, lowest they start at is 0.25mg, whereas in forums I most often hear people start at 2mg.

Its a weekly dose, and in research papers people titrated up after week 4. Ive heard variety from online forums.

So I wonder, those who used reta, how quickly you increased.

Im considering start with 2mg, increase to 3mg week later, then again to 4mg week after, and keep increasing every week until I reach 7 or 8 mg/ week. That is of course assuming I dont get overwhelmed by side effects.
Not planning to go past that since from lab research, going past 8mg/wk gives only fractional improvement in fat loss.

Is that true from experience?
Do you split your shots into 2x a week regimen?
How quickly did you titrated down to end?
How long was your treatment, and how much did you lose (lbs, start/end weight)?


Thanks for info if you choose to share.

 

[Meetketchup]

Like any drug or compound you only increase dosage when needed. You don't have a set schedule. lol If you are seeing great results from 2mg a week why would you increase to 4mg?

The schedule is how your body reacts to a compound. Body is not a textbook.

 

[elit3keraed]

Been on since April.

1st round was as fillows

Week
1: .5mg
2: 1mg
3: 1.5mg
4:1.5mg
5-6: 2mg
7: 2.5
8-10: 3mg
11-12: 3.5mg
13-15: 4mg
16+: 4.5

Something along those lines. I was doing E6D dosing though.


Then I tried 5 and hated it. I need my cut and went down to 2mg every 7 days


Then went from 2mg 2x a week to 4mg 2x a week over the course of like 3 weeks and have been at 8mg total weekly since 2nd week/3rd week of October.

Feel better with the split dosing

 

[Big_Jimmy434]

With Reta, you should definitely start low. I would say no more than 1-2mg and like @Meetketchup said, if its working then don't change it. It is possible to desensitize to GLPs over time. Always stay as low as possible.

 

[calf10]

Start low and stay low is the goal, as long as the appetite is suppressed. You dose up ONLY when needed. I started at 2mg/week (1mg Sunday, 1mg wednesday), increased dose after 3 weeks and continue increasing the dose AS needed. I was 253 and went down to 208 with consistent 2lbs weight loss weekly. I was comfortable with 2lbs weight loss weekly. Could I lose 5lbs a week consistently? Absolutely, the results are dose dependent. Be ready for potential health issues plus ugly lose skin is inevitable if you lose weight fast. Long story short, I dose my reta to reach 2lbs weekly weight loss - your appetite and scale tells you when and how much to titrate up. I never needed more than 6mg/week. The most dangerous side effect for me was anhedonia, watch your overall drive and emotions closely - secret nasty side effect a lot of folks do not realize.

 

[bigrond]

Having used these compounds i will tell you low and slow is the way to go. If you go up too fast you could have serious stomach issues like diarea or paralyzed stomach where your food does nothing but sit there. Start at 1 mg see how that hits you give it a wk if it did nothing 2mg and so on if it stops your hunger do not go any higher it takes 4 wks for blood levels to even out. Some people are very sensitive to these drugs. My wife after 1 yr on tirz is still on 1.25mg anymore makes her ill and she cant even look at food. For me 5 to 6 mg reta will fk me initially and then it mellows out 4mg gives me just slightly reduced hunger and is usually my sweet spot when using it for lipid improvements.