On 4mg Retatrutide

[xstah]

That is exactly what I am about to do as soon as the Cag arrives. What dose did you start with?

Info is scarce and varied on it. I’d start low, like 500mcg and see how you respond. Now I take equal parts to my Reta: 3mg each on Sunday/Wednesday

 

[J.S.]

That is exactly what I am about to do as soon as the Cag arrives. What dose did you start with?

So, the reading I’ve done on Cag , the dosage range in clinical trials was .3-4.5 mg. Would be wise to start low and titrate up every 4 weeks , something like .25 mg for four weeks , .5 for four and so on, with a max of 4.5 mg.
What’s being studied pretty big right now is combining Sema with Cag, starting both at .25 mg per week and increasing every four weeks , the max Sema dose will be lower then the max Cag dose , so once you reach the max Sema ,you would just increase Cag . This is all subjective due to everyone is not the same and the studies are still few.
Got to say ,I’m very interested in this Cag, probably going to try it just by itself at first,then give the combo a try at some point.

 

[RedRed82]

I have really enjoyed my retatrutide experience. I would definitely increase as slowly as possible. I felt like the appetite suppression for me was great in the beginning and then as I increased and my body adjusted it’s almost non existent now and I’ve ran it up to 8mg a week.

Would do that differently next time.

I noticed and increase in hr on days I didn’t do cardio. Totally anecdotal. But my resting hr sits around 70 beats a minute or less sometimes and in the mornings I would be at 90 beats a minute. I never had palpitations or would have noticed the increase otherwise. But since I do keep an eye on it I noticed.

I will do cardio in the AM and drink a body armor and my hr would hover in the 80’s. But was higher if I didn’t do my cardio. Not sure if it’s the Reta or cardio. But that’s my experience with that.


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Once you get up that high do you just taper off slowly or can you drop from 8/4/2 to none week to week or stay with every two to three weeks on taper


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[Wally954]

Nope. This is my first time. I noticed my Blood pressure to be slightly elevated recently.

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If you have never used a GLP before and 4 mg didn’t suppress your appetite. I would really question your source, 1 mg killed my appetite for three days straight, I had to force myself to eat, if I took 4 mg my first shot I wouldn’t be able to go to work for 3 days from the nausea and lethargy

 

[DeodatoFulci]

I was on a 1mg dose for 2 and a 1/2 months, and ive lost over 30lbs thus far. Ive titrated up to a 8mg dose since, but you should definitely feel something at 4mg. Maybe try another vendor.

 

[RedRed82]

I was on a 1mg dose for 2 and a 1/2 months, and ive lost over 30lbs thus far. Ive titrated up to a 8mg dose since, but you should definitely feel something at 4mg. Maybe try another vendor.

Wow that’s pretty good stuff on 1 mg


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[subweevil]

Reta does very little to control/ crush my appetite, and I'm good with that. All I've used I've sued from legit sources, never noticed any difference. My resting heart rate does go up a few ticks, usually around the 64 range, it jumps up to 68-70. It is doing a stellar job with all the other stuff. I started out super low doses, 1x a week, but found currently, I prefer 2mgs 2x per week.

 

[Captain_Furious]

Whay does everyone think about this new video from Dr. Trevor Bachmeyer about NOT doing low carb when using reta, and that by doing low carb, you're reducing the drug effectiveness pretty significantly? Of course, it's hard to figure up from down and left from right with all of these different theories and protocols beeing pushed by influencers as well as well-intentioned but misinformed users. Something to definitely chew on though...

NO low carbs with retatrutide?

 

[McPriimate]

I wonder about all the other appetitive behaviors that tirzepatide has been so good for - alcohol craving/use probably chief among them - with Reta. If it doesn’t do as much to crush appetite, I wonder if it won’t be as effective at damping those other cravings.

Tirzepatide - at least for the people it works for - has a marked effect. Was a great study I think first half of last year that looked at binge drinking frequency, amount, etc and the results were better than just about any other intervention I’ve seen. But it also seems to blunt hunger better than Reta, so wonder if the converse will be true for blunting (or not) the booze (and other substance?) cravings with Reta

Super interesting stuff all this. But if we can get the genpop to be less fat and less drunk, we’ll save the country many, many billions in health care costs (even if we have to pay some of those billions to LLY - and Iron Lion )


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[Captain_Furious]

I wonder about all the other appetitive behaviors that tirzepatide has been so good for - alcohol craving/use probably chief among them - with Reta. If it doesn’t do as much to crush appetite, I wonder if it won’t be as effective at damping those other cravings.

Tirzepatide - at least for the people it works for - has a marked effect. Was a great study I think first half of last year that looked at binge drinking frequency, amount, etc and the results were better than just about any other intervention I’ve seen. But it also seems to blunt hunger better than Reta, so wonder if the converse will be true for blunting (or not) the booze (and other substance?) cravings with Reta

Super interesting stuff all this. But if we can get the genpop to be less fat and less drunk, we’ll save the country many, many billions in health care costs (even if we have to pay some of those billions to LLY - and Iron Lion )


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I think the concern (correct me if I'm wrong) with the semaglutide is the muscle wasting issues, and same with tirzepatide to a lesser degree. Doesn't appear to be an issue with retatrutide so far, but they're still in phase 3, so who knows... I just know it's been helpful for me personally, but maybe not a game changer. Game changer is diet and working with my coach @Meetketchup

I have seen a BIG improvement in blood marker health, so no matter what, I'll continue to run reta even when I reverse out, just at super minimal doses to see those blood marker improvements cemented in place.

 

[Halfnatty666]

I get hungry on it but I get full fast! You can still get hungry but it should make you feel full faster then you usually would eat

 

[Bolan]

If you have never used a GLP before and 4 mg didn’t suppress your appetite. I would really question your source, 1 mg killed my appetite for three days straight, I had to force myself to eat, if I took 4 mg my first shot I wouldn’t be able to go to work for 3 days from the nausea and lethargy

Same... I took 1 2mg shot of Reta and I couldn't even get in my maintenance cals or protein... couldn't shit for 3 days. Gut wasn't right for an entire month. I know how to get lean, Reta is just an excuse to eat garbage.

 

[Bigjape34]

Same... I took 1 2mg shot of Reta and I couldn't even get in my maintenance cals or protein... couldn't shit for 3 days. Gut wasn't right for an entire month. I know how to get lean, Reta is just an excuse to eat garbage.

I wouldn’t even have thought To use it for that purpose haha but it kinda makes sense some people do. I’m using 1.5mg a week and still able to get all my food in. I personally notice I might climb a lb or 2 the day after a shot but that’s about it negatively for me personally

 

[J.S.]

If you have never used a GLP before and 4 mg didn’t suppress your appetite. I would really question your source, 1 mg killed my appetite for three days straight, I had to force myself to eat, if I took 4 mg my first shot I wouldn’t be able to go to work for 3 days from the nausea and lethargy

Well, that could work both ways, if 1mg or even less is nuking your appetite then maybe your getting Sema, see how that works ? I’ve used both , Sema killed my appetite at .25 mg and I lost 80 lbs in 9 months, Reta has a completely different feel, but I know it’s working when I’m on it. Lastly, I trust both sources I got my Reta from, both well respected on this forum.
I’m saying , both effects people differently, from one person to the next.

 

[Hughmangoes]

Same... I took 1 2mg shot of Reta and I couldn't even get in my maintenance cals or protein... couldn't shit for 3 days. Gut wasn't right for an entire month. I know how to get lean, Reta is just an excuse to eat garbage.

With the amount of food guys like you have to eat just to maintain your physique, what even is the point of glps? I look at them as mostly appetite suppressants and all the other benefits seem to be exaggerated

 

[Wally954]

My weight loss stalled big time for almost 2 months when I was taking in low carbs on Reta,it picked up again as soon as I added carbs back in . I believe u need some carbs to maximize weight loss on glps. It’s like my metabolism shut down on low carbs. A scoop of rice with my high protein meals really woke up the weight loss

 

[McPriimate]

My weight loss stalled big time for almost 2 months when I was taking in low carbs on Reta,it picked up again as soon as I added carbs back in . I believe u need some carbs to maximize weight loss on glps. It’s like my metabolism shut down on low carbs. A scoop of rice with my high protein meals really woke up the weight loss

While I can’t prove it, I suspect this is particularly true with Reta, given that the glucagon agonism is one of the mechanisms of action. Need some carbs or you’ll likely pull more protein in to the process (muscle loss) and I would bet that the “extra cal burn” you get from Reta is more efficient if you have reasonable carbs in your diet. If so, it would require a bit different balance of macros than what people traditionally target in a cut (meaning keeping the carb ratio just a touch higher - to both keep the burn up and spare muscle). How much it matters practically vs theoretically, I have no idea. Might be talking tens of grams and tens of calories burned difference or many tens of grams of macros and hundreds of calories difference if done perfectly (iow, might or might not matter practically).

Reta is some super interesting shit and I don’t think we have all the nuances figured out just yet. But I’m glad it’s a tool in the box!


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[BBSQ5]

Whay does everyone think about this new video from Dr. Trevor Bachmeyer about NOT doing low carb when using reta, and that by doing low carb, you're reducing the drug effectiveness pretty significantly? Of course, it's hard to figure up from down and left from right with all of these different theories and protocols beeing pushed by influencers as well as well-intentioned but misinformed users. Something to definitely chew on though...

NO low carbs with retatrutide?

There’s been some misconception on his video and folks are blasting him for what he’s stating. Dr. Bachmeyer is a very respected source for what he gives out information wise and all for pretty much free.

I think he was trying to drive home the glucagon piece of Reta and the fact that the Lily trial data coming out states that Reta has show to put patients in trial into ketosis and that if you are one of those low carb diets, you can run the risk of ketosis and whatnot.

I am by no means an expert on the subject, but reading the data, I think he is basically stating that you don’t have to be on a low carb diet for Reta to work efficiently. I don’t think that he is making a blanket statement that carb cycling at 500g+ per day makes Reta work better or more efficiently, but that’s just my analyzation in the subject of not having to cut carbs down for Reta to work.

 

[Bolan]

With the amount of food guys like you have to eat just to maintain your physique, what even is the point of glps? I look at them as mostly appetite suppressants and all the other benefits seem to be exaggerated

Exactly, I was going to use it to get my Glucose under control not
because I was fat.
I feel bad for the people on them, because when they come off
the fat comes right back.

 

[Cypher]

I started taking 4 mg Reta last week.
Just had my second shot this Friday.
So far, I have not felt anything significant at this dose.
My apetite is roughly the same. I am a naturally big eater.
Most people reported to have reduced apatite within 24 to 72 hours of first injection.

This is making me question my source. Got it from vitalitypeptides.co.uk

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Retatrutide isn’t a pure incretin like semaglutide or tirzepatide. Because retatrutide also includes a glucagon component, both the dosing (mg) and the formulation are inherently different. For me, reta does a decent job of reducing food noise, but as I’ve said before, the benefits it provides beyond appetite suppression alone are truly worth their weight in gold.

I’m currently taking a retatrutide blend with cagrilintide (8mg reta 2mg cagri), which absolutely knocks appetite suppression out of the park. I’m not hungry, but I’m not getting that nauseous feeling I usually experience with semaglutide or tirzepatide.

 

[McPriimate]

Retatrutide isn’t a pure incretin like semaglutide or tirzepatide. Because retatrutide also includes a glucagon component, both the dosing (mg) and the formulation are inherently different. For me, reta does a decent job of reducing food noise, but as I’ve said before, the benefits it provides beyond appetite suppression alone are truly worth their weight in gold.

I’m currently taking a retatrutide blend with cagrilintide (8mg reta 2mg cagri), which absolutely knocks appetite suppression out of the park. I’m not hungry, but I’m not getting that nauseous feeling I usually experience with semaglutide or tirzepatide.

I think this is a great combo. I’m currently at 4 Reta and 2mg tirz, but might switch the tirz for cagri or try just Reta at 4 or 6mg

Defo want to stay on Reta (or tirz) for the non-weight benefits. All the data line up for Tirz being incredibly positive in several non-appetite/weight related ways, and it’s likely Reta will be as good or better (prelim stuff looks good but time will tell for sure)


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[Thedoorman445]

I’m currently on 4 mg of Retatrutide, and honestly I’ve been able to eat just fine. If anything, I actually feel a bit more hungry on it. That said, I still lost around 20 pounds in the first month, so it’s clearly doing something in the background even if appetite suppression isn’t super noticeable for me. I’ve thought about adding cagrilintide, but I’m not convinced I really need it at this point. Since things are still moving in the right direction, I’m probably going to hold off unless that changes. This is also my first GLP and haven't done Semaglutide or Tirzepatide so I really don't know on what kind of appetite suppression I am suppose to have.

 

[Wally954]

Well, that could work both ways, if 1mg or even less is nuking your appetite then maybe your getting Sema, see how that works ? I’ve used both , Sema killed my appetite at .25 mg and I lost 80 lbs in 9 months, Reta has a completely different feel, but I know it’s working when I’m on it. Lastly, I trust both sources I got my Reta from, both well respected on this forum.
I’m saying , both effects people differently, from one person to the next.

No sir, I’ve tried 6 or 7 different vendors and it’s always the same, I know how reta affects me. everyone who’s used Reta that never used a GLP before starts at 1 mg and the suppression works good, people who’ve never use it and start at 2 mg usually get diarrhea for a week and feel like shit. It doesn’t give me diarrhea, but it makes me constipated, but after the first month or two, the suppression goes away big time and you need to up the dosage. I know people who were on semiglutide and Reta doesn’t work for them at all even at 10 mg a week. If your body has never used a GLP‘s then it doesn’t take much Reta to suppress your appetite.if u have used tirz or semi before using Reta then the Reta might not even work for you as far as appetite suppression.

 

[URYDadLeft]

I got 20mg vial for 180 pounds. Thats around 220 usd I believe

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I just got ten 20mg vials for $155. You're paying 10x more than you need to.

 

[Thedoorman445]

I just got ten 20mg vials for $155. You're paying 10x more than you need to.

That's about how much I get mine for - you won't find that deal on here though. You need to scout another forum related to GLP-1 to find those vendors. But once you do, you realize how cheap this shit is.

 

[Farmerdan]

That's about how much I get mine for - you won't find that deal on here though. You need to scout another forum related to GLP-1 to find those vendors. But once you do, you realize how cheap this shit is.

YD are most definitely board sponsors that offer international pricing.