Injectable Proviron

[Juicelord]

On paper, 5 mg of injected mesterolone ought to be the equal of like 100 mg oral. Seems like such a formulation would be very popular but maybe theres a good reason its not.

Anybody know a source? Anybody tried injected Proviron?

 

[JC33]

I’ve been saying the same thing about masteron with no ester. Maybe someone will chime in lol

 

[Calibig46]

From info I could find with just a Google search injectable proviron seems to have horrible pip.

 

[Vision]

Proviron (Mesterolone) was used in INJECTION form as an anti-depressant, not just oral.

Injectable Proviron, could it ever make a comeback? The drug was studied in the mid-1970s
Injectable Proviron, could it ever make a comeback? The drug was studied in the mid-1970s

Injectable Proviron, could it ever make a comeback? - The drug was studied in the treatment of depression in men along with mesterolone in the mid-1970s but was never introduced for medical use.

Proviron as stimulatory drug like a nootropic..

Proviron (Mesterolone) was used in INJECTION form as an anti-depressant, not just oral.

Mesterolone as an anti-depressant even as INJECTION form.. That's right, Mesterolone was once used anti-depressant in INJECTION form, as mostof us know it was used in the oral application for the same intent..
One will argue that Masteron (Drostanolone) is the same, it's NOT..

Here's some old info that we all may know, yet below is some info about it's short term use in oily form..

m
The German hormone manufacturer Schering did tests in the seventies on an injectable analogue of the anabolic steroid mesterolone, the active substance in Proviron. We, the industrious compilers of this free webzine, discovered this friday afternoon when we were browsing through patents. Researchers at Schering gave mesterolone cypionate and classic mesterolone to men suffering from depression – and the results were promising.
Mesterolone
Mesterolone resembles DHT, the androgen metabolite of testosterone. The difference with DHT is that mesterolone has a methyl group on C1 and DHT does not. The methyl group makes mesterolone into a very mild steroid. So mild that, according to studies done in the 1970s, oral doses of 75-150 g daily have a negligible effect on the body's own testosterone synthesis.
Effect of mesterolone on serum FSH, LH and plasma testosterone in normal men - PubMed

At the same time the 1-alpha-methyl group inhibits enzymes that neutralise mesterolone in the body. That's why mesterolone can be taken orally.
Most handbooks say that mesterolone is too mild for male steroids users. In the past steroids users have taken mesterolone as an anti-oestrogen but without much success, and to restart the body's own testosterone production after a course of steroids - with even less success.
Mesterolone as an anti-depressant

[TABLE="width: 150, align: right"]
[TR]
[TD="align: right"][/TD]
[/TR]
[/TABLE]
In the 1980s researchers at Schering published a couple of studies in which they had got small groups of men suffering from depression to take 300-450 mg mesterolone daily for a period of six weeks.
The effects of mesterolone, a male sex hormone in depressed patients (a double blind controlled study) - PubMed
This treatment was successful in most of the subjects.

In another study the researchers compared mesterolone with the anti-depressant amitriptyline.

A comparison of the antidepressant effects of a synthetic androgen (mesterolone) and amitriptyline in depressed men - PubMed
http://According to the researchers...tive, but mesterolone had fewer side effects.

Mesterolone cypionate
Schering's research on the anti-depressive effect of mesterolone started in the 1970s, as the discovery of a patent dating from 1974 shows.
US3908007A - Treatment of mental depression - Google Patents

In that patent the researchers explicitly mention mesterolone and its esters, one of which was named mesterolone cypionate [structural formula shown below].

According to the patent, mesterolone cypionate is particularly suitable for oral use, but can be injected too.
The patent also happens to cover the use of nearly all possible analogues of mesterolone as anti-depressants. The figure below gives an idea of the dosages that the researchers used.

Mesterolone as a stimulant
According to the patent, the researchers administered mesterolone and its esters to subjects in both low and high dosages. The high dosages, shown above, had an anti-depressant effect, and the low dosages a stimulatory effect. The stimulatory dose for mesterolone administered orally lies somewhere between 1 and 20 mg, according to the patent.
"It has now been found that mesterolone and its esters exhibit a psychostimulating effect at lower doses", the researchers wrote. "The desired psychotropic and CNS-stimulating effects of mesterolone occur within 2-3 hours after administration."
Source:
US3908007A - Treatment of mental depression - Google Patents

Learn MORE about PROVIRON ::HERE::
http://www.anabolicsteroidforums.com/threads/90391-Why-you-should-use-Proviron-or-Masteron-with-Tren-(the-benefits)

 

[mae_geri]

On paper, 5 mg of injected mesterolone ought to be the equal of like 100 mg oral. Seems like such a formulation would be very popular but maybe theres a good reason its not.

Anybody know a source? Anybody tried injected Proviron?

¨Can I ask you why you want that? Oral Proviron is not toxic at all (compared to other orals). And the question is what's the half life of the injectable version. The Orals Proviron has a half life of 12-13hrs. So you need to take it at least twice a day. When this is the same case with the inectable one, than you've to pin more then once.....I don't know injectable proviron, I'm just curious. thx

 

[Vision]

¨Can I ask you why you want that? Oral Proviron is not toxic at all (compared to other orals). And the question is what's the half life of the injectable version. The Orals Proviron has a half life of 12-13hrs. So you need to take it at least twice a day. When this is the same case with the inectable one, than you've to pin more then once.....I don't know injectable proviron, I'm just curious. thx

My man my man

 

[Juicelord]

¨Can I ask you why you want that? Oral Proviron is not toxic at all (compared to other orals). And the question is what's the half life of the injectable version. The Orals Proviron has a half life of 12-13hrs. So you need to take it at least twice a day. When this is the same case with the inectable one, than you've to pin more then once.....I don't know injectable proviron, I'm just curious. thx

The main reason is efficiency; oral provi has an oral bioavailability of something like 5-10%, injected is 100%! Provi raws are expensive….Starting to make sense?

 

[Vision]

The main reason is efficiency; oral provi has an oral bioavailability of something like 5-10%, injected is 100%! Provi raws are expensive….Starting to make sense?

The oral bioavailability may only be 3%, however listen to this - its thermal half-life is a whopping 12 to 14 hours! So get this, it's fast and rapidly absorbed too! But the best part? It will bind to the SHBG by up to 58%! That's more free test, and less estrogen.

Taking this drug three times daily works wonders! Don't be deceived by low bioavailability - these drugs are specially made for a reason. It's not all about high drug plasma serums, it's about where and how these drugs bind and the pathways they take. Exciting stuff, right?!

 

[Glycomann]

The main reason is efficiency; oral provi has an oral bioavailability of something like 5-10%, injected is 100%! Provi raws are expensive….Starting to make sense?

This doesn't make sense. The cypionate form was at a dosage of 50 - 500 mg every 2 weeks. Oral dosage would be on maximum 100 mg/d so 1400 mg/2w. So if oral of 1400 is equivalent to 275 injectable and injectable represents 100% absorption then oral absorption is approximately 275/1400 ~ 20%. Oral dose of 100 mg/d is generous. Bayer's package insert recommends up to 75 mg/d.

 

[Astro95]

I don’t think injectable anything is 100% bio available. More than oral yes, but 100% maybe IV has the highest bioavailability. Just an uneducated opinion if it is cool lol

 

[mae_geri]

The main reason is efficiency; oral provi has an oral bioavailability of something like 5-10%, injected is 100%! Provi raws are expensive….Starting to make sense?

Even if that's true, what's in it for you? Many pro bodybuilders use and have used Proviron Oral in the last 4-8 weeks before a competition (up to 150mg a day). And with the right diet and structure, they have reached their goal. Are you a pro bodybuilder? What are your goals? Just for information: Proviron is anabolic on paper but completely useless at building muscle in real life. This is because Proviron is also subject to modification by the 3-alpha-HSD enzyme found in muscle cells. Like Vision already said, the main reason why someone (for example TRT) takes proviron is that it binds to SHBG like no other oral and this releases more free test and less estrogen.

Don't get me wrong i just want to help, maybe you can find another (better) way to reach your goal instead of looking for something that doesn't necessarily get you anywhere......

 

[Glycomann]

I don’t think injectable anything is 100% bio available. More than oral yes, but 100% maybe IV has the highest bioavailability. Just an uneducated opinion if it is cool lol

So your assertion is that my estimate is not close enough for you? You can find research studies of radio labeled steroid that trace the entire dose. I would argue pretty close. What is your estimate and based on what?

 

[Astro95]

So your assertion is that my estimate is not close enough for you? You can find research studies of radio labeled steroid that trace the entire dose. I would argue pretty close. What is your estimate and based on what?

I wasn’t replying to you, I didn’t even read your post. Simply on the assumption that it needs to be broken down and there will be loss of compound. I don’t have an estimate, I ended my post with just an uneducated opinion for a reason

 

[Meetketchup]

@Vision dropping some good knowledge here.

 

[Juicelord]

Even if that's true, what's in it for you? Many pro bodybuilders use and have used Proviron Oral in the last 4-8 weeks before a competition (up to 150mg a day). And with the right diet and structure, they have reached their goal. Are you a pro bodybuilder? What are your goals? Just for information: Proviron is anabolic on paper but completely useless at building muscle in real life. This is because Proviron is also subject to modification by the 3-alpha-HSD enzyme found in muscle cells. Like Vision already said, the main reason why someone (for example TRT) takes proviron is that it binds to SHBG like no other oral and this releases more free test and less estrogen.

Don't get me wrong i just want to help, maybe you can find another (better) way to reach your goal instead of looking for something that doesn't necessarily get you anywhere......

I like proviron, dont mind injecting and want more bang for my buck. I wonder why youre not getting this?

 

[JC33]

I don’t think injectable anything is 100% bio available. More than oral yes, but 100% maybe IV has the highest bioavailability. Just an uneducated opinion if it is cool lol

Wanna hangout later and IV some proviron with me??

Yea me and Astro were slammin provi together in a parking lot, good times

 

[MackVMT]

Wanna hangout later and IV some proviron with me??

Yea me and Astro were slammin provi together in a parking lot, good times

Why can't we just shoot some Provi in between the toes like heroin?
Possible gold mine?

 

[Astro95]

Wanna hangout later and IV some proviron with me??

Yea me and Astro were slammin provi together in a parking lot, good times

I only IV tren ace and humalog these days

 

[Juicelord]

Bostin Loyd over here

 

[Sirchon]

Wanna hangout later and IV some proviron with me??

Yea me and Astro were slammin provi together in a parking lot, good times

If I only had to do it once a week, I'd be down for a cocktail drip while I did my Emsculpt machine.

 

[mae_geri]

I like proviron, dont mind injecting and want more bang for my buck. I wonder why youre not getting this?

your statement doesn't answer my question. i was just trying to help. but anyway, have fun. (you'll get more "bang for your buck" with other better AAS, that's all)

 

[Juicelord]

Mae-geri, thats a front kick, ura-geri is a back kick, I am recalling some Karate lessons as a youngster…

Thanks for trying to help. I like provi because it raises free test to astronomical levels and has a nice mild effect elsewhere. Mast is similar, some would say, but harsher, for me. I take juice for the same reasons everyone else does: I like the effects they have on my body.

Imagine inj provi, 50 mg per mL, 5 mg a day would be like 75-100 mg oral, lets call it 5 mg = 100 mg, for simplicity. This means for the same quantity of raw mesterolone the injectable 10 mL vial would last 100 days, while 500 mg of oral would last 5 days. Thats the attraction
for me, I know it exists BUT there must be a reason ugls dont widely offer it.

If anyone knows a source or has tried it, thatd be great to hear about.

 

[mae_geri]

Mae-geri, thats a front kick, ura-geri is a back kick, I am recalling some Karate lessons as a youngster…

Thanks for trying to help. I like provi because it raises free test to astronomical levels and has a nice mild effect elsewhere. Mast is similar, some would say, but harsher, for me. I take juice for the same reasons everyone else does: I like the effects they have on my body.

Imagine inj provi, 50 mg per mL, 5 mg a day would be like 75-100 mg oral, lets call it 5 mg = 100 mg, for simplicity. This means for the same quantity of raw mesterolone the injectable 10 mL vial would last 100 days, while 500 mg of oral would last 5 days. Thats the attraction
for me, I know it exists BUT there must be a reason ugls dont widely offer it.

If anyone knows a source or has tried it, thatd be great to hear about.

Ura MAWASHI Geri is a hook kick.....known in semi contact karate, I do kyokushin full contact. Back Kick is Ushiro Geri. But also this is not the case now...anyway...good luck for your research about inj. prov.

 

[Anabolix8]

Injectable mesterolone (Proviron) is rare because its primary use is androgen support without significant anabolic effects, and oral bioavailability is already decent due to its methylation. Injectable versions might not offer enough advantage to justify production or demand.

On paper, 5 mg of injected mesterolone ought to be the equal of like 100 mg oral. Seems like such a formulation would be very popular but maybe theres a good reason its not.

Anybody know a source? Anybody tried injected Proviron?

 

[jj210tx]

On paper, 5 mg of injected mesterolone ought to be the equal of like 100 mg oral. Seems like such a formulation would be very popular but maybe theres a good reason its not.

Anybody know a source? Anybody tried injected Proviron?

I thought they were literally the same compound...

 

[Juicelord]

Huh? Mesterolone is the chemical name, Proviron the trade or brand name.

Injected is way more efficient, thats the question; why is injectable provi so rare?