Yeah, who knows, right? Nobody really knows.
Does primo suppress E2? Who knows. It’s all anecdotes and unofficial user reports from people running stuff outside any medical oversight.
And if we’re talking anecdotes, then when primo leaves your system, in theory it stops having any effect on whatever it was affecting.
But things aren’t always that simple and straightforward.
For example, once you’re suppressed, it’s not that easy to get everything going again. It’s not like you stop taking testosterone and everything just goes back to how it was before, the effects last much longer than you might think.