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Nandrolone decanoate ester is most efficient for muscle growth over NPP

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Nandrolone decanoate "long ester" is most efficient for muscle growth over NPP
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Discover the most effective way to use Nandrolone for maximum muscle growth! According to a groundbreaking 1997 study by andrologists at the University of Sydney, chemical athletes looking to build muscle should opt for a preparation with the longest ester, highest concentration, and inject it into their gluteus muscle instead of their shoulders. This research provides valuable insights for those seeking to optimize their muscle-building potential with Nandrolone.

In a groundbreaking study, researchers conducted an experiment involving 23 healthy, non-obese men aged between 18 and 40. These brave souls were divided into 4 groups and injected with different nandrolone preparations, each containing 100 mg of the steroid.
Over the course of the next 32 days, the researchers diligently measured the levels of nandrolone in the men's bodies each day. Talk about dedication!

The first group received a 100 mg injection of nandrolone phenylpropionate in the buttock. This fancy compound used to be a key ingredient in Organon's Durabolin, and can now be found in UG preparations. It's like a blast from the past! The 100 mg dose was mixed in a 4ml ampoule of groundnut oil.
Moving on to the second group, they also received a 100 mg injection, but this time with nandrolone decanoate, the star of Deca-Durabolin. Fancy stuff!
The third group got a similar treatment with 100 mg of nandrolone decanoate, but this time it was concentrated in just 1 ml of groundnut oil. Talk about efficiency!

Last but not least, the fourth group had their 100 mg dose of nandrolone decanoate injected into their shoulder muscle, dissolved in 1 ml of groundnut oil. Ouch!
So there you have it, folks! A riveting tale of injections, nandrolone, and groundnut oil. Who knew science could be so entertaining?

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Exciting Findings!

Nandrolone phenylpropionate delivers a quick peak in the bloodstream, but this peak diminishes after 4-5 days. On the other hand, Nandrolone decanoate does not cause a peak, but it remains in the system for a longer period of time.
Interestingly, injecting a more concentrated form of nandrolone, such as 1 ml instead of 4 ml, results in more of the substance entering the body. Additionally, injecting into the buttocks leads to higher levels of nandrolone in the system compared to injecting into the shoulders.

In the table provided, the shaded section displays the total amount of nandrolone present in the body after four separate injections. Pay close attention to the area under the curve for more insights.
This groundbreaking research was partially funded by Organon Australia and was published in the Journal of Pharmacology and Experimental Therapeutics in April 1997. The study, conducted by Charles F. Minto, Christopher Howe, Susan Wishart, Ann J. Conway, and David J. Handelsman, delves into the Pharmacokinetics and Pharmacodynamics of Nandrolone Esters in Oil Vehicle, exploring the effects of ester, injection site, and injection volume.

Source: J Pharmacol Exp Ther. 1997 Apr; 281 (1): 93-102.

Exciting Abstract:

Our study focused on healthy men who underwent plasma sampling for nandrolone, testosterone, and inhibin measurements before and after receiving a single i.m. injection of 100 mg of nandrolone ester in arachis oil. The participants were divided into different groups receiving either nandrolone phenylpropionate or nandrolone decanoate injected into the gluteal muscle in varying volumes of arachis oil.

The results showed that plasma nandrolone concentrations were significantly influenced by the type of ester and injection site, with the phenylpropionate ester leading to higher and earlier peaks compared to the decanoate ester. Interestingly, the 1-ml gluteal injection of nandrolone decanoate resulted in the highest bioavailability and peak nandrolone levels.

Furthermore, plasma testosterone concentrations were also affected by the ester and injection site, with the phenylpropionate ester causing rapid but brief suppression, while the 1-ml gluteal injection led to sustained suppression. Additionally, plasma inhibin concentrations were significantly influenced by injection volume and site, with the lowest levels observed after the 1-ml gluteal injection of nandrolone decanoate.

In conclusion, our study highlights the importance of considering the side-chain ester, injection site, and volume when studying the pharmacokinetics and pharmacodynamics of nandrolone esters in an oil vehicle in men. These findings provide valuable insights into optimizing the bioavailability and physiological effects of nandrolone esters for future research and clinical applications.
 
well, it is always said that this sport is a marathon, not a sprint.
long esters remain in the body for a longer time and therefore act for a longer period.
it is what you do in the chronic that counts not what you do in the acute
 
well, it is always said that this sport is a marathon, not a sprint.
long esters remain in the body for a longer time and therefore act for a longer period.
it is what you do in the chronic that counts not what you do in the acute
Oh, so true! The heavier and longer the ester, the more likely it is to stick around and cause some trouble by chatting it up with other enzymes on a cellular level. And guess what? It might even wake up those sleepy enzymes that are usually just lounging around loitering. How exciting!

So true! This whole interaction could potentially mess with specific groups in your body. So, for those of you who are a bit sensitive, I highly recommend using something that doesn't stick around and cause any drama, try to avoid things that hang around and loiter. You know, something that knows how to come and go without causing a scene. No fuss no muss.

NPP......
 
I wonder how injection frequency is taken into account. NPP would probably have a much greater result taken every day. This way you will not have ups and downs in blood concentration. I actually like short esters for this very reason. It's easier to control and adjust dosages as needed. It hits you fast but also gets out of your system fast.

Even with longer test esters. I once experimented with extremely high doses of test. It took a few weeks before I felt normal again.

Tri tren is probably the worst thing I ever experienced.
 
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Npp is my preference. I can tweak the dose quickly, major 19nor sides for me but they make me strong a bull 🤣

I’m going to hang myself

I only pin high volume & traps/chest only
precisely, It's multifunctional. Some years back I ran NPP at 700mg, felt like a completely different drug IN A GOOD WAY.
I stay leaner, yet still full round bellies. It shines so much better when I feed it nutrients.
Test cyp and NPP is all I need...
 
precisely, It's multifunctional. Some years back I ran NPP at 700mg, felt like a completely different drug IN A GOOD WAY.
I stay leaner, yet still full round bellies. It shines so much better when I feed it nutrients.
Test cyp and NPP is all I need...
New thank you reaction?? 😱
 
deca i always prefer longer esters
Same, I can't stand pinning high volume anymore.
The deca and small frequent injections keeps peaks and troughs extremely stable which for us older guys seem to allow for less sides (especially anxiety) in some people. All user dependent. No right or wrong - Love nandrolone.
 
Now would like be similar to the different esters of Tren? I really like Tren Ace, then you have E or Hex for long esters. Would the long esters of Tren be better in the long run?
 
Now would like be similar to the different esters of Tren? I really like Tren Ace, then you have E or Hex for long esters. Would the long esters of Tren be better in the long run?
I'll chime in here since Ive ran all 3 esters over the years. Im a huge fan of Hex personally. With Ace I have to tap out around week 7 or 8 before the mental sides get too much and the shit sleep make it not worth it (even with all the necessary ancillaries and supps). With Enth I get pretty horrible physical sides that make it a non-starter for me that all the caber in the world doesnt help. I have yet to experience anything negative with Hex other than a bit more trouble staying asleep... cardio hasnt suffered/lipids havent taken any real big hit/no feeling of losing IQ points by the day/no crazy psychotic thoughts. The nutrition partioning has been just as good as my runs with Ace, which combined with the basically nonexistent sides means you can run this compound for far longer. Thats my 2c.
 
I'll chime in here since Ive ran all 3 esters over the years. Im a huge fan of Hex personally. With Ace I have to tap out around week 7 or 8 before the mental sides get too much and the shit sleep make it not worth it (even with all the necessary ancillaries and supps). With Enth I get pretty horrible physical sides that make it a non-starter for me that all the caber in the world doesnt help. I have yet to experience anything negative with Hex other than a bit more trouble staying asleep... cardio hasnt suffered/lipids havent taken any real big hit/no feeling of losing IQ points by the day/no crazy psychotic thoughts. The nutrition partioning has been just as good as my runs with Ace, which combined with the basically nonexistent sides means you can run this compound for far longer. Thats my 2c.

Well I haven’t used Tren E so that’s up in the air. Tren Ace I’m loving and no crazy sides other than my appetite for sex is so bad I can’t get enough. Now my first run with Hex I made it 5wks before I had to drop it. The sides had me thinking crazy shit and I wanted to crawl out of my skin.

Gotta say that Tren Ace is probably the only one I will use from now on. If it ain’t broke don’t fix it.
 

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