Sublingual (Troche) Oxandrolone (Anavar)
Benefits of Sublingual Oxandrolone (Anavar) Administration
Sublingual oxandrolone (anavar) administration bypasses the liver and enters the bloodstream directly. This has a number of advantages, the most significant of which is that sublingual oxandrolone is much easier on the liver than oral oxandrolone (anavar).
The fact that sublingual oxandrolone has less impact on the liver has the great benefit of making this medication a viable option for patients with liver issues, or even for patients without liver issues that need a higher dose for long periods of time (up to years of continuous use).
Additionally sublingual delivery will prevent the estimated 10% metabolisation that occurs in first-pass metabolism, making doses taken sublingually significantly stronger than a tablet taken orally.
Another notable benefit to sublingual oxandrolone (anavar) is that it is absorbed more quickly than when taken orally. The rapid absorbtion of a sublingual dose so it can be used as needed (such as before exercise) rather than being taken on a set schedule.
This makes sublingual oxandrolone (anavar) an excellent tool for getting the most precise results when combined with traditional hormone replacement therapy (testosterone).
Disadvantages of Sublingual Oxandrolone (Anavar)
Administration
One downside to sublingual oxandrolone (anavar) administration is that it can be tricky to dose properly. This is because the oxandrolone (anavar) must be placed under the tongue and allowed to dissolve completely before swallowing.
If any oxandrolone is swallowed it will be processed by the liver and may cause liver stress similarly to oral administration. Another disadvantage of sublingual oxandrolone (anavar) administration is that it can cause local irritation to the soft tissue in the mouth over time.
The biggest issue found with sublingual oxandrolone (anavar) is that, if the patient is using this medication to decrease SHBG, sublingual delivery will have reduced effect compared to oral administration. This reduced effect of oxandrolone (anavar) on lowering SHBG is found to occur due to skipping first-pass in the liver.
SHBG is found in high concentrations in the liver, and oxandrolone (anavar) is found to bind with high affinity to this binding protein. Sublingual oxandrolone (anavar) will still have a significant impact on lowering SHBG, however this is a consideration that must be taken by your clinician in choosing dose and delivery method.
Which Route of Administration is Best?
The best route of administration for oxandrolone (anavar) depends on the individual’s goals and medical conditions. For people who want the most convenient or need to lower sex hormone binding globulin (SHBG), oral oxandrolone is probably the best choice.
However, for people who are concerned about liver toxicity or who need a more rapidly absorbed medication, sublingual oxandrolone is a better option. Your clinician can help you decide which route of administration is best for you, based on your individual goals and medical conditions.