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TRT sub Q

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hoyle21

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Recently changed my dosing to subq daily injections and thought I’d share some information. I’ve really been struggling with IM dosing. I’m very hematocrit sensitive and couldn’t get it under control with standard blood donations. I moved to subq and have seen a huge difference. My hematocrit is now under control, my sleep is much improved, and workouts have also improved, I’m actually seeing gains again. Probably seeing even testosterone levels with no peeks and troughs and I appear to be responding to it very well.

If you are having issues with severely elevated hematocrit, give it a try


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hoyle21 said:
Recently changed my dosing to subq daily injections and thought I’d share some information. I’ve really been struggling with IM dosing. I’m very hematocrit sensitive and couldn’t get it under control with standard blood donations. I moved to subq and have seen a huge difference. My hematocrit is now under control, my sleep is much improved, and workouts have also improved, I’m actually seeing gains again. Probably seeing even testosterone levels with no peeks and troughs and I appear to be responding to it very well.

If you are having issues with severely elevated hematocrit, give it a try


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Click to expand...


Great to know! I’m switching to sub Q as well, I’ve had similar issues w my HCT

What’s your TRT dose and how often are u injecting?
 
Conmike41 said:
Great to know! I’m switching to sub Q as well, I’ve had similar issues w my HCT

What’s your TRT dose and how often are u injecting?
Click to expand...

I was taking 200mg every 10 days, now I’m taking 10 units every day. It’s the exact same amount by week, just taken every day.


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Startingover said:
Interesting..
Thoughts as to why hct would lower via sub Q compared to im??
Click to expand...

According to the research it absorbs slower and creates a steady state testosterone level. IM injections cause peaks and troughs, even when the esters. The peaks are what causes the spike in hematocrit.


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hoyle21 said:
According to the research it absorbs slower and creates a steady state testosterone level. IM injections cause peaks and troughs, even when the esters. The peaks are what causes the spike in hematocrit.


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I am thinking it was most likely the switch to daily injections and not the sub-Q injections that made the difference, but it is good that you found a solution that works for you.
 
hoyle21 said:
Yes sub q is daily injections


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I believe Fearsome is more so asking how often were you injecting IM before. If it was 2x or 3x weekly, then switch to every day typically does have a significant impact on lowering HCT,E2 etc. Like you said…. peaks and troughs.

That being said I’ve never tried SubQ daily. I’ve always stuck to 3x weekly IM since all of the more experienced guys make it seem like that’s the true and true method, but every post I see like this makes me more tempted to try it.

Do you have any quantifiable HCT numbers from before you switched and now so we can see the difference it made for you?


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AndyLutz11 said:
I believe Fearsome is more so asking how often were you injecting IM before. If it was 2x or 3x weekly, then switch to every day typically does have a significant impact on lowering HCT,E2 etc. Like you said…. peaks and troughs.

That being said I’ve never tried SubQ daily. I’ve always stuck to 3x weekly IM since all of the more experienced guys make it seem like that’s the true and true method, but every post I see like this makes me more tempted to try it.

Do you have any quantifiable HCT numbers from before you switched and now so we can see the difference it made for you?


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Yeah, my TRY isn’t self prescribed it’s all being monitored by a physician I’ve found that prefers Testosterone levels while in TRT to be in the upper third of normal. I had been consistently in the 60’s even giving blood monthly. I now am hovering around 51-52. Still just a few months into the process, but seeing good results so far and I’ve gone to standard 56 day blood donations.

I’m sure the smaller, every day dosing does help with the peaks, but physiologically subq injections are absorbed much slower, that’s the case for all medicine injected subq
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hoyle21 said:
I was taking 200mg every 10 days, now I’m taking 10 units every day. It’s the exact same amount by week, just taken every day.


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What's the vial concentration, 250mg/ml?
 
Is your Total Test the same as when you were doing IM ? Trying to understand how Subq Test can be absorbed the same as IM. Thanks!
 
My Hematocrit never seems to fluctuate much, but my Hemoglobin does, the best thing I’ve done for that is staying well hydrated, does a good job on that.
 
GYMnTONIC said:
Smaller dosages more often always equals a better result. No matter what the compound.

Emerics 10mg prop ED HRT regiment works well for 99% of men and puts them in normal healthy ranges.
Click to expand...
Do you feel the same regarding GLP’s? (Reta, etc)?
 
pcf said:
Do you feel the same regarding GLP’s? (Reta, etc)?
Click to expand...
I was referring to AAS but if you look at it standard terms. Any medication or drug is going to have more intense results and effects, the higher the dosage. Including side effects. The issue with GLPs and other meds is that they have a very different absoption rate and also a very different half-life then "hormones" per say.

Here is a study however that may indeed meet the criteria or any questions you have sir

Alternative dosing regimens of GLP‐1 receptor agonists may reduce costs and maintain weight loss efficacy - PMC

To discover alternative dosing regimens of incretin mimetics that simultaneously reduce costs and maintain weight loss efficacy. As a secondary objective, we used our results to explore how allocating a limited incretin mimetics budget could affect ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
GYMnTONIC said:
Smaller dosages more often always equals a better result. No matter what the compound.

Emerics 10mg prop ED HRT regiment works well for 99% of men and puts them in normal healthy ranges.
Click to expand...

This is actually true in a lot of medicine. Thats why doctors will often add another drug instead of increasing the dose. You see that a lot in hypertension patients.


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pcf said:
Is your Total Test the same as when you were doing IM ? Trying to understand how Subq Test can be absorbed the same as IM. Thanks!
Click to expand...

Didn’t test my T levels, not sure why, might be an insurance thing for timing. This study focuses more on safety but does mention levels are the same

pubmed.ncbi.nlm.nih.gov

Testosterone Therapy With Subcutaneous Injections: A Safe, Practical, and Reasonable Option - PubMed

Although studies directly comparing the safety of SC vs IM administration of testosterone esters are desirable, clinicians should consider discussing the SC route with their patients because it is easier to self-administer and has the potential to improve patient adherence.
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov


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Seems studies point to subQ over IM..
Worth checking out for 4/8 weeks subQ

Labs and see if any changes...
 

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