Yk11

[codem]

What was everyone's experience or what is everyone's experience currently running yk11? Wes sold a batch if I'm not mistaken.

I ran 20mg/day ampm split for 4 weeks, finished my vial the other day.

Im at around 18% bf so I didn't get any crazy vascularity, but I have gone up in weight on every machine I workout with.

 

[Startingover]

20mgs total?
Or 20mgs am/pm=40mgs per day? Either way,should see some changes..
Of course training,nutrition has to be in check for maximum results.
My dose was less than 20mgs a day and I was very pleased.
Yk also burns fat..
Least for me it did..
Also pumps are inssne!!
Love this compound!!

 

[Meetketchup]

Overrated in my opinion. It’s like a weak Anavar even at high dosages. I’m referring to the injectable as the oral is bioavailabiy useless. Plus we don’t have any long term studies on it.

These miraculous claims people have about it always come without any measurable evidence. “Burns fat, massive pumps, explosive strength.”

I’ve used it multiple times and many clients as well. Haven’t seen much in results. I’d much rather run a mild cycle of var for more gains.

There are a select few on here that swear by it and glad it works for them but it’s a tiny population.

If you do run it a would do so in a deficit.

 

[Startingover]

I wouldn't call it miraculous..
I'd call it,what was experienced 3× I've ran it!!
I also know the compliments given while running it each time!!
Also my starting dose was very low..
I have nothing but respect for you MK.
But lots of times you come off as know all be all end of story type shit man...

 

[Meetketchup]

I wouldn't call it miraculous..
I'd call it,what was experienced 3× I've ran it!!
I also know the compliments given while running it each time!!
Also my starting dose was very low..
I have nothing but respect for you MK.
But lots of times you come off as know all be all end of story type shit man...

That type of bullshit ad hominem shows no respect. I gave my OPINION. Didn’t know you’re the only one who can offer one.

Put me on ignore.

 

[Guti20]

Idk gonna give the injectable a shot as an add on to the end of my bulk last 6-8 weeks. We’ll see I was not impressed by the oral at all

 

[rollin-tumblin]

big ol' thread on it here
Looky

 

[codem]

20mgs total?
Or 20mgs am/pm=40mgs per day? Either way,should see some changes..
Of course training,nutrition has to be in check for maximum results.
My dose was less than 20mgs a day and I was very pleased.
Yk also burns fat..
Least for me it did..
Also pumps are inssne!!
Love this compound!!

20mg total so 10mg am 10mg pm.

Overrated in my opinion. It’s like a weak Anavar even at high dosages. I’m referring to the injectable as the oral is bioavailabiy useless. Plus we don’t have any long term studies on it.

These miraculous claims people have about it always come without any measurable evidence. “Burns fat, massive pumps, explosive strength.”

I’ve used it multiple times and many clients as well. Haven’t seen much in results. I’d much rather run a mild cycle of var for more gains.

There are a select few on here that swear by it and glad it works for them but it’s a tiny population.

If you do run it a would do so in a deficit.

It most definitely is like a weak anabolic, it reminded me of tren the first two weeks, by the third week it no longer had any effect on my CNS.

I definitely wouldn't say it gave me massive strength increases, but it did help.

For the price? I would have rather spent $70 on some TNE.

Until I get to the size I want to be, I'm planning on sticking to testosterone cycles anyways.

Gear feels like a waste, I could have went without ever touching tren, var, yk11. At least until I had put on more muscle.

You live and you learn

 

[dcdogz]

Its kinda like proviron. Mild and has its niche/use case.

 

[GYMnTONIC]

I gained 10lbs , leaned out a little and absolutely got much fuller. Constant compliments. In under 8 weeks.. cost me like $120 for 3 bottles.

No sides except maybe prostate but I haven't determined if that is the yk or the pwo I use daily.

It's a very impressive compound imo.

Cost wise can other things do more? Sure real dbol and anadrol are gonna make u way bigger and at a much lower price.

Yk11 is a myostatin inhibitor. Comparing it to an anabolic steroid doesn't make sense. May as well compare it to HGH too while we're at it?

Financially it's pricy, I def agree.

It's a clean ,safe run. I like it . When I run orals I have high BP, acne, oily skin, mood, etc. so for me this is a very nice alternative.

It might not be for everyone but I personally really like it. I don't like the 2* Ed INJ.

 

[Jbswole40]

I cant give a great review i ran a bullshit company stuff couple yrs ago,
I believe i did 30mg a day split am pm dosing..i was running few other things at the time,,
Would love try this on test only.
I still have bottle or 2 from wes,
Mayb spring time im give it a go

 

[McPriimate]

Its kinda like proviron. Mild and has its niche/use case.

And like proviron there will be people who love it and people who don’t. And people in between…

I’ve been loving proviron with test/eq/npp. I like my run with MK but it’s similarly an add-on like proviron - as in like less of a driver compared to aas but still doing something (at least by strength/scale).

As to whether it’s worth it, depends also on the person and how they value things. It is to me, but I could see the beef on expense if that’s a limiter


Sent from my iPhone using Tapatalk

 

[Conmike41]

Overrated in my opinion. It’s like a weak Anavar even at high dosages. I’m referring to the injectable as the oral is bioavailabiy useless. Plus we don’t have any long term studies on it.

These miraculous claims people have about it always come without any measurable evidence. “Burns fat, massive pumps, explosive strength.”

I’ve used it multiple times and many clients as well. Haven’t seen much in results. I’d much rather run a mild cycle of var for more gains.

There are a select few on here that swear by it and glad it works for them but it’s a tiny population.

If you do run it a would do so in a deficit.

I ran it for 6 weeks and definitely got stronger in the gym and fuller. Put on about 5 lbs and body composition stayed the same

Was it placebo?!?! Maybe ..

Like @GYMnTONIC mentioned, people at work were telling me I looked fuller etc

I’ve haven’t run orals yet… and I agree w you … I do hate the fact that there’s no real human studies

I’m curious though how it compares to Anavar, Winstrol or even Tren with regards to toxicity, impact on liver, kidney, lipids etc

Also curious to see if the gains stick around

Might run it again while just on TRT to see if I notice any real changes

 

[Conmike41]

Also

Found this article today about an athlete with myostatin deficiency

Pretty interesting read

C

Thread 'Genetics and Myostatin news article'

Dec 19, 2025

Interesting read about genetics and myostatin

I wonder how many people out there have similar genetics

Sometimes I think I might produce too much myostatin

The mystery of the ‘Hercules gene’ – the blessing and curse of sports stars

Having extra muscle mass sounds like a benefit for athletes, but the reality is far more complicated

www.nytimes.com

• Conmike41
• Replies: 3
• Forum: Muscle Central

• 

Makes me wonder how many others with similar genetics are out there

We always talk about genetics in bodybuilding and how some people respond to compounds etc

Some people are hyper responsive to gear and grow on 300 mg test

Other guys need grams of gear to grow

 

[Startingover]

I ran it for 6 weeks and definitely got stronger in the gym and fuller. Put on about 5 lbs and body composition stayed the same

Was it placebo?!?! Maybe ..

Like @GYMnTONIC mentioned, people at work were telling me I looked fuller etc

I’ve haven’t run orals yet… and I agree w you … I do hate the fact that there’s no real human studies

I’m curious though how it compares to Anavar, Winstrol or even Tren with regards to toxicity, impact on liver, kidney, lipids etc

Also curious to see if the gains stick around

Might run it again while just on TRT to see if I notice any real changes

Ran it with my trt 150 mgs cyp.
Results happened for me.
3 times I've ran it.
Runs of 4 weeks 1st time.
Other 2 runs 4 to 6 weeks..

 

[Jbswole40]

I ran it for 6 weeks and definitely got stronger in the gym and fuller. Put on about 5 lbs and body composition stayed the same

Was it placebo?!?! Maybe ..

Like @GYMnTONIC mentioned, people at work were telling me I looked fuller etc

I’ve haven’t run orals yet… and I agree w you … I do hate the fact that there’s no real human studies

I’m curious though how it compares to Anavar, Winstrol or even Tren with regards to toxicity, impact on liver, kidney, lipids etc

Also curious to see if the gains stick around

Might run it again while just on TRT to see if I notice any real changes

Nice post!!
Placebo effect is definitely a real thing with many.
Just saying in general.
Were doing human studies right here at asf daily..
And another thing,gains sticking around..is totally up to u,no matter the compound..

 

[FearsomeCOR]

And like proviron there will be people who love it and people who don’t. And people in between…

I’ve been loving proviron with test/eq/npp. I like my run with MK but it’s similarly an add-on like proviron - as in like less of a driver compared to aas but still doing something (at least by strength/scale).

As to whether it’s worth it, depends also on the person and how they value things. It is to me, but I could see the beef on expense if that’s a limiter


Sent from my iPhone using Tapatalk

Right, but what makes this more interesting than proviron is the discrepancy in actual tissue gained it seems.

People do love or hate proviron, but that’s more typically within feeling any mental boost or dryness.

Here we are seeing discrepancies of gaining seemingly 10lbs. That’s pretty drastic. Could come down to quality of product simply as well though.

 

[Meetketchup]

I ran it for 6 weeks and definitely got stronger in the gym and fuller. Put on about 5 lbs and body composition stayed the same

Was it placebo?!?! Maybe ..

Putting on 5lbs of muscle with little to no fat gain on any compound is extremely rare. I'm in no way questioning your gains just asking how you measured that? Dexa? Mirror?

I ask because I have never seen metrics like that from the compound other than hearing someone say it.

As far as how it effects bloods. It hits some peoples liver values and cholesterol levels while not much with others. I wonder if purity is an issue as the stuff is often faked. I don't question Wes' product I am referring to many others on the market. So who knows what's really in it.

Believe me, if I found great results from it, I would keep running it.

 

[Bolan]

Been using the stuff for 3-4 years... and I'll continue to use it for its
Myostatin inhibiting effects. Shit has always worked for me!!!


YK11 is a synthetic, steroidal Selective Androgen Receptor Modulator (SARM) that acts as a potent myostatin inhibitor. It is an experimental compound that is not approved for human or veterinary use by the FDA and is a prohibited substance in professional sports.

Mechanism as a Myostatin Inhibitor
YK11 primarily inhibits myostatin through a unique dual mechanism:

• Upregulation of Follistatin: YK11 increases the expression of follistatin, a naturally occurring glycoprotein that binds to and neutralizes myostatin. Myostatin acts as a natural "brake" on muscle growth, and by inhibiting it, YK11 removes this limitation, promoting muscle cell proliferation and differentiation.
• Androgen Receptor (AR) Partial Agonism: YK11 binds to androgen receptors in muscle tissue, though it acts as only a partial agonist. This interaction helps trigger the cellular pathways that lead to increased follistatin production and subsequent muscle anabolism.

Availability and Use
While YK11 is effective in preclinical in vitro and animal studies, it is not a clinically validated or approved drug. It is typically sold as a "research chemical" and is not intended for human consumption.
The compound has been studied in animal models in various forms, including oral administration and in vivo injections in research settings. The use of such non-approved substances carries significant health risks, as its long-term effects and safety in humans are poorly characterized.
Myostatin inhibitors are a subject of legitimate medical research for treating muscle-wasting conditions like muscular dystrophy, sarcopenia (age-related muscle loss), and cachexia. However, these clinical trials use specific, regulated compounds (e.g., domagrozumab, apitegromab) and are conducted under strict medical supervision.

 

[Conmike41]

Putting on 5lbs of muscle with little to no fat gain on any compound is extremely rare. I'm in no way questioning your gains just asking how you measured that? Dexa? Mirror?

I ask because I have never seen metrics like that from the compound other than hearing someone say it.

As far as how it effects bloods. It hits some peoples liver values and cholesterol levels while not much with others. I wonder if purity is an issue as the stuff is often faked. I don't question Wes' product I am referring to many others on the market. So who knows what's really in it.

Believe me, if I found great results from it, I would keep running it.

Mirror my man, these results were subjective

Appreciate your experience and perspective brother! I’ve learned a lot from your posts

 

[Meetketchup]

Mirror my man, these results were subjective

Appreciate your experience and perspective brother! I’ve learned a lot from your posts

I appreciate that. We all learn from each other.

 

[FearsomeCOR]

I gained 10lbs , leaned out a little and absolutely got much fuller. Constant compliments. In under 8 weeks.. cost me like $120 for 3 bottles.

No sides except maybe prostate but I haven't determined if that is the yk or the pwo I use daily.

It's a very impressive compound imo.

Cost wise can other things do more? Sure real dbol and anadrol are gonna make u way bigger and at a much lower price.

Yk11 is a myostatin inhibitor. Comparing it to an anabolic steroid doesn't make sense. May as well compare it to HGH too while we're at it?

Financially it's pricy, I def agree.

It's a clean ,safe run. I like it . When I run orals I have high BP, acne, oily skin, mood, etc. so for me this is a very nice alternative.

It might not be for everyone but I personally really like it. I don't like the 2* Ed INJ.

Are we talking 10lbs up of tissue? Or glycogen and fullness that went away after?

 

[GYMnTONIC]

Are we talking 10lbs up of tissue? Or glycogen and fullness that went away after?

I haven't been off long enough to say but the crazy part was like I mentioned I not only didn't increase calories. I barely ate bc of the reta I'm on

Had I jacked up my cals I guarantee I could have added 20lbs of weight. Even if I gained 3lbs of muscle out of the 10, for a 47 year old man in a calorie deficit and not training to 100% intensity this is a bad ass gain. It's actually super impressive.

When I ran mk677 as a comparison I ate prob 5000cals and I trained 5-6 days a week, much harder. I gained 20lbs in 2-3 months and a month or two off it I was still up 12lbs.

On this I may have eaten 1-2k calories at most the whole time. I can't underestimate how big of a gain I made on this yk.

I will run it again in the near future and force calories in.

Remember guys I also haven't used anything except OTC products and my prescribed HRT for many years ..so my result is a true result.

Had I been on other AAS or hgh etc I couldn't make a legit claim.

I was also on reta which makes you lose weight and appetite..and I still gained 10lbs of weight.

 

[Omoplata]

Also

Found this article today about an athlete with myostatin deficiency

Pretty interesting read

C

Thread 'Genetics and Myostatin news article'

Dec 19, 2025

Interesting read about genetics and myostatin

I wonder how many people out there have similar genetics

Sometimes I think I might produce too much myostatin

The mystery of the ‘Hercules gene’ – the blessing and curse of sports stars

Having extra muscle mass sounds like a benefit for athletes, but the reality is far more complicated

www.nytimes.com

• Conmike41
• Replies: 3
• Forum: Muscle Central

• 

Makes me wonder how many others with similar genetics are out there

We always talk about genetics in bodybuilding and how some people respond to compounds etc

Some people are hyper responsive to gear and grow on 300 mg test

Other guys need grams of gear to grow

I think of the “The Gift” aka Heath when I read this.

He’s definitely an outlier and a source of motivation. YK-11 doesn’t have time under the research to make factual claims.

Regardless, opinions are like assholes and everyone is one.. or is the quote, everyone has one..?

 

[Bolan]

I haven't been off long enough to say but the crazy part was like I mentioned I not only didn't increase calories. I barely ate bc of the reta I'm on

Had I jacked up my cals I guarantee I could have added 20lbs of weight. Even if I gained 3lbs of muscle out of the 10, for a 47 year old man in a calorie deficit and not training to 100% intensity this is a bad ass gain. It's actually super impressive.

When I ran mk677 as a comparison I ate prob 5000cals and I trained 5-6 days a week, much harder. I gained 20lbs in 2-3 months and a month or two off it I was still up 12lbs.

On this I may have eaten 1-2k calories at most the whole time. I can't underestimate how big of a gain I made on this yk.

I will run it again in the near future and force calories in.

Remember guys I also haven't used anything except OTC products and my prescribed HRT for many years ..so my result is a true result.

Had I been on other AAS or hgh etc I couldn't make a legit claim.

I was also on reta which makes you lose weight and appetite..and I still gained 10lbs of weight.

I've run it on TRT....,. Still really really good.
Wes, that YK is going to last in your system for another 2-3 weeks after last pin.
I know people say 10# is mostly water and glycogen..,,,but acts like a androgen (hardner) so..... I am capable of keeping the weight I put on with the INJ-YK. No Im not gaining 10# but 2-3# after its all settled and out of the system.
I don't know how you did it on Reta... but that's nutty!!!! 10# on a 1-2k diet!

 

[Wardamn]

I gained 10lbs , leaned out a little and absolutely got much fuller. Constant compliments. In under 8 weeks.. cost me like $120 for 3 bottles.

No sides except maybe prostate but I haven't determined if that is the yk or the pwo I use daily.

It's a very impressive compound imo.

Cost wise can other things do more? Sure real dbol and anadrol are gonna make u way bigger and at a much lower price.

Yk11 is a myostatin inhibitor. Comparing it to an anabolic steroid doesn't make sense. May as well compare it to HGH too while we're at it?

Financially it's pricy, I def agree.

It's a clean ,safe run. I like it . When I run orals I have high BP, acne, oily skin, mood, etc. so for me this is a very nice alternative.

It might not be for everyone but I personally really like it. I don't like the 2* Ed INJ.

YK is an anabolic steroid by chemical structure. Comparing it to other anabolics is fair.

 

[Wardamn]

I've run it on TRT....,. Still really really good.
Wes, that YK is going to last in your system for another 2-3 weeks after last pin.
I know people say 10# is mostly water and glycogen..,,,but acts like a androgen (hardner) so..... I am capable of keeping the weight I put on with the INJ-YK. No Im not gaining 10# but 2-3# after its all settled and out of the system.
I don't know how you did it on Reta... but that's nutty!!!! 10# on a 1-2k diet!

It's hardening effect makes sense it was derived from DHT. It's basically a DHT derived steroid.

 

[Wardamn]

I've run it on TRT....,. Still really really good.
Wes, that YK is going to last in your system for another 2-3 weeks after last pin.
I know people say 10# is mostly water and glycogen..,,,but acts like a androgen (hardner) so..... I am capable of keeping the weight I put on with the INJ-YK. No Im not gaining 10# but 2-3# after its all settled and out of the system.
I don't know how you did it on Reta... but that's nutty!!!! 10# on a 1-2k diet!

double post

 

[Bolan]

YK11 is both a synthetic steroidal compound and a potent myostatin inhibitor. It is unique among compounds generally classified as Selective Androgen Receptor Modulators (SARMs) because of this dual mechanism of action.

Key Characteristics of YK11

• Steroidal Structure: Unlike most SARMs which are non-steroidal, YK11 has a steroidal backbone derived from dihydrotestosterone (DHT). This chemical configuration means it can engage in some molecular interactions similar to anabolic-androgenic steroids (AAS).
• Selective Androgen Receptor Modulator (SARM): YK11 is classified as a SARM because it selectively binds to androgen receptors (ARs) in muscle and bone tissue as a partial agonist, promoting anabolic activity.
• Myostatin Inhibitor: Its primary and most notable function is to promote muscle growth by significantly increasing the expression of follistatin, a natural protein that inhibits the activity of myostatin. Myostatin acts as a natural "brake" on muscle growth, and by inhibiting it, YK11 effectively removes a biological barrier to potential muscle development.

In summary, YK11 utilizes both androgen receptor activation and myostatin inhibition pathways to enhance muscle growth in research settings. It is an experimental compound that is not approved for medical use in humans.

 

[codem]

Are we talking 10lbs up of tissue? Or glycogen and fullness that went away after?

I personally did not get the glycogen and fullness tren gave me, I've been off yk11 a week now and have actually gotten bigger than I was on it. Not much but all yk11 did was increase strength for me.

I feel like my recovery is worse now off of yk11 though, on it, no DOMS, off of it, I'm sore again.