TRT/Primo/Var protocol advice

[pepsforpeeps]

I plan to start my first stack/cycle/blast (whatever you call it these days) in over a decade. I am currently on 200mg test cyp (TRT). With that I have been coasting around 1100 total test, 270 free test, and an elevated e2 of 93. I have had no sides from the elevated e2.

I have 4000mg of primo on hand and a bag of Anavar gummies (50mg x 30).

Back story: Late thirties, 5’9”, 184lbs. I was always avid lifter but let things slip away for a while (kids/work/life/booze). I have lost roughly 54 pounds since March 2026. Currently sitting around 13% bf. I have leaned up pretty good and feel 1000x better. Ideally, I would like to keep my Cyp where it’s at. I chose these compounds due to them being less “harsh” and to ease back into it. Any advice on a TRT/Primo/Var cycle would greatly appreciated. Looking to add some lean mass and stay dry.

Shoot me straight ladies. The research I have done is all over the place. Thanks in advance.

 

[Hablooblah]

Keeping your test at 200mg could be difficult given primos lowering effect on estradiol. I have no clue and cant know how it would effect you. Only bloodwork can. But if you did 200/200 youd likely end up with low e2. If it was me, I would bump test up and run a 2:1 test/primo (300/150 or 400/200) and do bloodwork at week 4 or 5 and id throw the anavar in a drawer and forget about it. Thats just what i would do.

 

[Rnduser1]

@Meetketchup

 

[pepsforpeeps]

Keeping your test at 200mg could be difficult given primos lowering effect on estradiol. I have no clue and cant know how it would effect you. Only bloodwork can. But if you did 200/200 youd likely end up with low e2. If it was me, I would bump test up and run a 2:1 test/primo (300/150 or 400/200) and do bloodwork at week 4 or 5 and id throw the anavar in a drawer and forget about it. Thats just what i would do.

Thanks! I get bloods done the first week of November. Just might have to get a little more test on board.

 

[Jack3d_Wabbit28]

Keeping your test at 200mg could be difficult given primos lowering effect on estradiol. I have no clue and cant know how it would effect you. Only bloodwork can. But if you did 200/200 youd likely end up with low e2. If it was me, I would bump test up and run a 2:1 test/primo (300/150 or 400/200) and do bloodwork at week 4 or 5 and id throw the anavar in a drawer and forget about it. Thats just what i would do.

Yeah what he said. I just finished up 600 test 300 primo and my e2 was 18. Felt fine though. First time having my e2 around there. I’m normally around 30-40 and like that better though. Ran that for 12-13 weeks and finished up around 750 test and 420 primo for total or 16 weeks. I felt good. Gains were solid. I also sprinkled in some var towards the end. First time trying out primo.

 

[Sickxlost]

I don’t get much e2 suppression from primo. Others do. I’d go a little higher on the test and add the primo in and see how you feel before bloods to verify.

 

[pepsforpeeps]

I don’t get much e2 suppression from primo. Others do. I’d go a little higher on the test and add the primo in and see how you feel before bloods to verify.

Okay thanks. Right now I’m doing 60mg every other day. Think I’ll bump it up to 100mg (350ish a week). And do 50mg (175ish a week) primo every other day with that.

 

[Sickxlost]

Okay thanks. Right now I’m doing 60mg every other day. Think I’ll bump it up to 100mg (350ish a week). And do 50mg (175ish a week) primo every other day with that.

That’s a great start brother.

E ester takes a while to saturate so I’d wait 5-6 weeks before getting bloods if you can.

 

[Musclemuscle]

Something I noticed when I ran primo is even though my e2 was 16, I didn't feel like it was too low and felt fine.. When I use an ai to control aromatization to a similar level, I feel drier in my joints and lethargic.. I typically like my e2 around 30ish so when I got the bloods back at half that, I was surprised.. I was running primo and test at 1:1

 

[Sickxlost]

Something I noticed when I ran primo is even though my e2 was 16, I didn't feel like it was too low and felt fine.. When I use an ai to control aromatization to a similar level, I feel drier in my joints and lethargic.. I typically like my e2 around 30ish so when I got the bloods back at half that, I was surprised.. I was running primo and test at 1:1

A lot of AIs inhibit e2 and that seems to make people feel a little worse when it’s slow.

I’m similar when running mast for e2 control

 

[19NorFan]

The e2 suppression from Primo, Mast and other DHTs is individual dependent.

My suggestion would be to lose some more weight, get down to 170 - 174 pounds, before starting a mass building cycle. At 13% BF you're too close to the upper limit of fat % IMO to go into a gaining phase.

 

[pepsforpeeps]

The e2 suppression from Primo, Mast and other DHTs is individual dependent.

My suggestion would be to lose some more weight, get down to 170 - 174 pounds, before starting a mass building cycle. At 13% BF you're too close to the upper limit of fat % IMO to go into a gaining phase.

Yah, that has been running through my mind as well. I appreciate you calling me fat in a nice way! Haha

 

[Knarfster]

Yeah what he said. I just finished up 600 test 300 primo and my e2 was 18. Felt fine though. First time having my e2 around there. I’m normally around 30-40 and like that better though. Ran that for 12-13 weeks and finished up around 750 test and 420 primo for total or 16 weeks. I felt good. Gains were solid. I also sprinkled in some var towards the end. First time trying out primo.

I ran 400 test 600 Primo and my E2 ended up at 2.5. Hence my DHB run. 2.5 to 3 times as anabolic as primo running 280mg/week and so far my E2 is fine.

 

[McPriimate]

Yeah what he said. I just finished up 600 test 300 primo and my e2 was 18. Felt fine though. First time having my e2 around there. I’m normally around 30-40 and like that better though. Ran that for 12-13 weeks and finished up around 750 test and 420 primo for total or 16 weeks. I felt good. Gains were solid. I also sprinkled in some var towards the end. First time trying out primo.

I just finished my first primo run and e2 was 24 on test of ~1800. Normally it’d be in the 70’s or so at that test level and I feel good there, but until the results came back I’d have sworn my E2 was a little high - at least 50-60’s if not even higher. Same thing with primo at 40-60% of test (the above was 80%) - felt maybe a bit high but was lower than expected. All good, just not what that level of E2 felt like with other combos (mast, eq, NPP, just test, etc)

Thought it was just me, so it’s interesting to hear this from someone else too


Sent from my iPhone using Tapatalk

 

[McPriimate]

Yeah what he said. I just finished up 600 test 300 primo and my e2 was 18. Felt fine though. First time having my e2 around there. I’m normally around 30-40 and like that better though. Ran that for 12-13 weeks and finished up around 750 test and 420 primo for total or 16 weeks. I felt good. Gains were solid. I also sprinkled in some var towards the end. First time trying out primo.

I just finished my first primo run and e2 was 24 on test of ~1800. Normally it’d be in the 70’s or so at that test level and I feel good there, but until the results came back I’d have sworn my E2 was a little high - at least 50-60’s if not even higher. Same thing with primo at 40-60% of test (the above was 80%) - felt maybe a bit high but was lower than expected. All good, just not what that level of E2 felt like with other combos (mast, eq, NPP, just test, etc)

Thought it was just me, so it’s interesting to hear this from someone else too


Sent from my iPhone using Tapatalk

 

[StarTrakZack]

I ran 400 test 600 Primo and my E2 ended up at 2.5. Hence my DHB run. 2.5 to 3 times as anabolic as primo running 280mg/week and so far my E2 is fine.

YUCK that must've been miserable I can't even imagine... I know the "reference range" is 20-50pg/ml, but I've noticed I tend to do better and have zero symptoms with it even higher (recent labs on just 250-300mg of Test was 74pg/ml and felt GREAT) and if mine even gets down to 35-40 I start to get all the classic "low e2" symptoms. Currently running Test/EQ/Var so I'm keeping a very close eye on it and trying not to let the EQ lower estradiol too much. I stayed away from Primo forever partially because I was worried about crashing e2, then ended up running EQ lol what an idiot