First of all, delivery matters.
Taking oral and taking injectable is drastically different, when you take 1mg oral, that milligram nvkes your liver at once, that puts immense load on the liver because it has a rate at which it metabolizes toxins, everything thats above that rate causes what we consider as liver damage, your liver is literally built to handle toxins, handling toxins is no problem, its when you exceed its metabolic rate that the left over toxins have time to damage your liver.
in all anecdotes on forums we see 2 groups of mtren users, mild elevation or severe elevation of liver enzymes, coincidentally it always boils down to oral or injectable usage. when using injectable, the metribolone disperses its way through your bloodstream, binding to androgen receptors, which means very little metribolone is left over for your liver to handle, which it does easily, remember, its built for toxins. yes, over the day its cummatively still 1mg of mtren, but the delivery to the liver is drastically dispersed instead of a big assault on the liver, remember what i said about exceeding the metabolic rate?
second of all, when you inject metribolone in ur bloodstream, it flows through ur body and starts binding to ar's before reaching the liver, right? well the oral version gets broken down heavily before it reaches the blood, and even then it managed to deliver a 15k-10k rating, imagine what bypassing that liver assault can deliver, probably double the rating if you ask me. i dont think anyone here understands how insanely androgenic metribolone injectable should be compared to oral, because lets say 1mg of oral was rated at 10k 15k, what reached the blood after getting broken down and raping the liver, was probably half that or even less. so the ar affinity is probably even higher.
third of all, almost all humans alive got terrible thyroid, especially us bodybuilders since we run crazy stuff, thyroid is quite literally the most important thing in the body for detox, so even when using a mega heavy delivery system as oral, and using mgs and having bad thyroid, some still pull off 8 or 12 weeks heavy cycles.
4th of all, the study is trash, it comes from 1967, and it was done on severly sick FEMALES, this has several drastic points that influence toxicity:
1. being sick fucks your entire toxicity metabolism, let alone if youre severly sick.
2. being sick rapes your thyroid
3. females barely have androgen receptors, which means a fuck ton of mtren was flowing through their blood unbinded, raping the liver as it flows.
4. they didnt have any sort of liver support
5. the delivery system was oral, which means the dose they used, lets say 1mg, asaulted the liver all at the same time, far exceeding the liver metabolic rate (which js basically 0 because of being female, severly sick, low thyroid, and no androgen receptors to slow down the assault on the liver)
after all, it was a small group of females too, and the research was done in 1967.
fifth of all, literally nobody uses as much liver support as needed. no further explanation needed.
anyhow, everyone here also seems to forget that working out pushes ur enzymes above 100, seeing forums reach 150 is not that worrying if u ask me (considering metribolone's rep)
lastly, because metribolones higher molar mass and dosing in micrograms, it drastically drastically less molecules in the blood, so there js wayyy lesss accummiliation in the brain compared to conventional tren.
finally, we can inject a high dose split in multiple injections to further slow down the liver strain, making it essentially as harmful as a 1l of beer (euros drink like 2l daily and live to 80)
