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Bummed about Bloodwork, 3 months TRT

Bloopetron

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Full results attached.

A little over 3 months on TRT. First 6 weeks 90mg per week, rest of time 105mg per week. Injecting 15mg every other day right now along with 250IU HCG right after

T went from 400-500 to 1050ng/dl.

Free T went from ~12ish to 28pg/ml

So that is great, thrilled about that.

My LDL unfortunately raised from low 80s to 102,

My glucose also has been slowly rising for months. I got it down to 80 back in March when I was on 2IU hgh and enclo. Thought I had room to run so pushed the hgh to 4IU each night following all meals but decreased back to 2-2.5IU once I saw fasting glucose in AM results show low 90’s. No change in hgh dose since starting TRT and it’s continued to climb, now at 100.

Diet is high carb, high protein, low fat especially saturated fat. I do try to load up on some simple carbs in morning with protein as well as concentrated around lifting sessions.

I lift 4-5 times a week, moderate to high rep hypertrophy work usually to failure. Squats are probably the only thing I don’t take to true failure until the last pendulum squat set.

8-10k steps per day, I could be better on the intentional cardio but walking around my hilly neighborhood I can get into zone 2. Especially when pushing my daughters stroller at a brisk pace on the incline parts.

I feel great, all of the usual benefits one gets from replacement doses of T but the glucose and LDL trends are starting to annoy me haha

Am I over thinking things or do you think more cardio, better diet, and possibly changes to meds (either removal of GH or addition of ezetimbe) could help
 

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My opinion...Definitely Ezitimebe and 250-500mg metformin. Metformin gets a bad rap but its a super beneficial drug for glucose control as well as longevity. It gets a reputation for hurting muscle growth because it activates AMPK, an energy-regulating pathway that can suppress mTOR, which helps drive muscle protein synthesis.
But those studies were done in older males with no TRT or even tracked testosterone levels. Hell, not even guys who lifted. Ive made substantial gains all while running 500mg/day metformin. Came off and on it deoending on carb intake bg levels etc...no difference...
 
My opinion...Definitely Ezitimebe and 250-500mg metformin. Metformin gets a bad rap but its a super beneficial drug for glucose control as well as longevity. It gets a reputation for hurting muscle growth because it activates AMPK, an energy-regulating pathway that can suppress mTOR, which helps drive muscle protein synthesis.
But those studies were done in older males with no TRT or even tracked testosterone levels. Hell, not even guys who lifted. Ive made substantial gains all while running 500mg/day metformin. Came off and on it deoending on carb intake bg levels etc...no difference...
Appreciate it, yeah ez seems to be widely recommended. I see mixed reviews on metformin so good to see you’ve had positive experiences. What kind of blood sugar numbers did you see after a few months of met usage?
 
Berberine works too. Metformin sends my GI south. Berberine doesn't and it works for me. Also, watch your A1c. It's more of a long term marker for your glucose status. Get a glucose meter if you don't have one It will help you dial in your doses.
 

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