There are studies that say otherwise. It can be protective and stop it before it starts. Now if you're getting gyno and/or ED issues during cycle, should probably take caber. But you can deploy p5p in advance and possibly limit the rise of itDont use supplements like p5p to mitigate steroid sufe effects like prolactin, it doesn't work.
Yep works great for me as long as i am proactive & not reactiveThere are studies that say otherwise. It can be protective and stop it before it starts. Now if you're getting gyno and/or ED issues during cycle, should probably take caber. But you can deploy p5p in advance and possibly limit the rise of it
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Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercise - PubMed
Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercisepubmed.ncbi.nlm.nih.gov

I don't know about that. I started P5P a week before my last NPP run and ran it all the way through. On 300 NPP my prolactin never went above 8ng/ml. Seemed to work just fine for me.You need caber. Its from prolactin. 250mcg 2x a week. Dont use supplements like p5p to mitigate steroid sufe effects like prolactin, it doesn't work.
But yeah, get bloodwork first to confirm.
It really does work for low dosage NPP cycleI don't know about that. I started P5P a week before my last NPP run and ran it all the way through. On 300 NPP my prolactin never went above 8ng/ml. Seemed to work just fine for me.
Yea, I suppose there is a chance if I really pushed the dosage up it may have diminishing returns but it did what I needed it to at that dose.It really does work for low dosage NPP cycle
No shit huh..ed problem non existent, now actually having orgasm is another thing on tren/deca/npp..i will have sweat out 10lbs of water catching cramps trying to finish lol.sometimes i just fake it and try again later. Like buff said take your ANCILLARIES!you guys with dick problems on NPP and deca blame it on the compound. I use good amounts of both. Run a little higher test, take p5p off Amazon, take your AI. Check your blood work. I had ED problems on DEca 20 years ago because I just took test and deca and didn't take any preventative protocols. The opposite now happens. I started cycle with 300 NPP with 600 deca for first 5 weeks of current cycle. Dick has opposite problem. Always hard. Dropped the npp and remain on 600 deca. Same problem, piece of steel down there
Glad I'm not the only one that's used this methodsometimes i just fake it and try again later.

Agree with you 100%. I use NPP in every cycle and if, like you said, its deployed early it will help keep prolactin down. If prolactin is already high it does nothing. Definitely a must use on an NPP run IMOThere are studies that say otherwise. It can be protective and stop it before it starts. Now if you're getting gyno and/or ED issues during cycle, should probably take caber. But you can deploy p5p in advance and possibly limit the rise of it
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Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercise - PubMed
Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercisepubmed.ncbi.nlm.nih.gov
The extra mile you can run is a bonus for your lady brother. Yeah the cramps. holy fuck man. As of a year ago, I said I wont do the trens . I was running the deca and tren. Talk about nothing better than thatNo shit huh..ed problem non existent, now actually having orgasm is another thing on tren/deca/npp..i will have sweat out 10lbs of water catching cramps trying to finish lol.sometimes i just fake it and try again later. Like buff said take your ANCILLARIES!
Those cramps in the abs are the worst. Even if I can get off on 19-nors, I gotta beat the crampsNo shit huh..ed problem non existent, now actually having orgasm is another thing on tren/deca/npp..i will have sweat out 10lbs of water catching cramps trying to finish lol.sometimes i just fake it and try again later. Like buff said take your ANCILLARIES!

I was gonna ask the question on here for past year but never did. My abs are always locking up real bad. So bad. you have no idea. Happens during sex if I'm doing it from the side. happens if I do the old one handed pushup position. Its pain in un imaginable levels. ABS just popping through hard as rock. Shit happens if I laugh at somethingThose cramps in the abs are the worst. Even if I can get off on 19-nors, I gotta beat the cramps![]()
I was referring to rapid increases from steroid use. Nandrolone does almost nothing to my prolactin, but tren is very hard to control without proper medication. Context is key, and I never said p5p has no impact on prolactin, I was specifically talking about how certain steroids can have a massive increase in prolactin and using p5p to mitigate it has a minimal impact.There are studies that say otherwise. It can be protective and stop it before it starts. Now if you're getting gyno and/or ED issues during cycle, should probably take caber. But you can deploy p5p in advance and possibly limit the rise of it
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Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercise - PubMed
Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercisepubmed.ncbi.nlm.nih.gov
Definitely prolactin, no doubt! You should always be running low doses of HCG/HMG for E2, and caber no matter what for prolactin. Definitely run labs for E2, any 19-NOR will hit your prolactin issues in the headI've used npp on my last blast with test and experienced ed during sex for the first time. I loved the body change results from npp but not the limpness lol. Is there anything that can help with this for my next blast? I'm already using Cialis everyday and don't have the problem when not using npp.
I didn't know about the link to possible neuropathy. Thanks for this info. I don't ever mega dose any supplements anyway but it's definitely good to know.And besides the point, using massive doses of B6 long term is not safe, as it has been linked to possible nerve damage. Compared to other b vitamins, it actually has a relatively low safety net.
I don't know anyone that is taking 1000mg a day of P5P. Most ppl are taking 100-200mg and per your first link....I was referring to rapid increases from steroid use. Nandrolone does almost nothing to my prolactin, but tren is very hard to control without proper medication. Context is key, and I never said p5p has no impact on prolactin, I was specifically talking about how certain steroids can have a massive increase in prolactin and using p5p to mitigate it has a minimal impact.
And besides the point, using massive doses of B6 long term is not safe, as it has been linked to possible nerve damage. Compared to other b vitamins, it actually has a relatively low safety net.
The Role of Vitamin B6 in Peripheral Neuropathy: A Systematic Review - PMC
Introduction: Vitamin B6 is a water-soluble vitamin that is naturally present in many foods and is accessible in many dietary supplements. The three natural forms are pyridoxine, pyridoxal, and pyridoxamine. Both vitamin B6 deficiency and high B6 ...pmc.ncbi.nlm.nih.gov
https://www.tga.gov.au/news/safety-updates/peripheral-neuropathy-supplementary-vitamin-b6-pyridoxine
Vitamin B6 (pyridoxine) and peripheral neuropathy
www.medsafe.govt.nz
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Polyneuropathy due to Vitamin B6 hypervitaminosis: A case series and call for more education
Polyneuropathy due to Vitamin B6 hypervitaminosis: A case series and call for more educationruralneuropractice.com
Vitamin B6 Toxicity Secondary to Daily Multivitamin Use: A Case Report - PMC
Vitamin B6 is a water-soluble vitamin that is an important cofactor in various metabolic processes. Although rare, its consumption can sometimes result in toxicity, which typically presents with peripheral neuropathy in the early stage. While ...pmc.ncbi.nlm.nih.gov
However, none of the studies had sensory nerve damage at a daily intake below 200 mg of pyridoxine per day

