Healing Peptides, do they help? Lets find out!

It is officially official, I am going in for surgery on my neck. I have had pain in my right elbow, numbness in my right hand, and a horrific loss of strength in my right tricep. To show just how much of a loss of strength, I used to be able to move 70 pounds, several times, with each tricep alone. Now my right tricep has a lot of trouble even moving 30 pounds and will simply not engage at all over 40 pounds. 45 pounds might as well be 500 pounds in as far as I can move the weight, yet I can move 40 pounds 6 full tricep reps.


This has been slowly getting worse since December. I have been seeing a Chiropractor while going through the traditional channels. He managed to fix many little issues I did not know I had, but I feel a lot better in those areas now that they are fixed. If your insurance covers a Chiropractor, I recommend seeing one just for a joint tune up. Well worth the copay.


Two weeks ago I had an MRI and last Friday I finally saw an Orthopedic Surgeon. He showed me what my spine looks like and explained that the only fix for it is surgery. He looked at his calendar and saw he had a cancellation for April 19th. We had been talking and he is a body builder. Not the "get huge and compete" kind, but more of the "look fricken awesome and be healthier" kind - which is my goal. He told me he is supposed to move all his other patients up, filling in the spot, but then he smiled and said "The bodybuilding community is pretty small, we have to stick together. I am giving you the spot, just don't tell my other patients. You need to get back to the gym as soon as you can." And I suddenly had a date for surgery a scant 1.5 weeks away! I accepted the date and started the ball rolling on it.


I then talked to my chiropractor, who I had added to all the testing results so he got a copy of my x-rays and MRI. He said that is the result he expected after seeing the test results and said we would meet one more time before my surgery to go over the rest of my joints and then call it quits for now. I setup a second opinion with another orthopedic group and had that meeting this morning. Interestingly enough, due to HIPPA I actually had to authorize myself as someone allowed to receive my test results or they could not give them to me. I had done so, so I had copies of everything to bring with. The new place told me the same thing the original surgeon said, so that is that, I am headed for the knife.


Here is my expertly drawn picture of what is wrong:





Those two bumps were caused decades ago when I smacked my head VERY hard onto the bottom of the pool. What we do in our youth comes back to haunt us later. They are going to cut out the part of the bone that has those two bumps which is on the C7 vertebrae. In the process, the liquid between C6 and C7 will drain away, so when they replace the bone with one from a bone bank, they are going to make it larger and cause C6 and C7 to fuse together. They said I will not notice the loss of bend there since there is very little bend to start with.


They will cut my throat and go in from the front for this. For 2 weeks afterwards I will not be able to lift more than 5 pounds, and then another 4 weeks of no more than 10 pounds, and then most likely released for "lift as your body tells you it can handle". I am to start light cardio on day one (walking around the neighborhood), but as soon as my neck brace is off (2 weeks) I am to move to moderate cardio level (as my body allows).


So, healing is what you all came in to read about, right? I provided that information so that I could talk about healing peptides and what I am going to be taking to help me heal faster. This is a golden opportunity for me to find out if the healing peptides ACTUALLY do heal. In my next post, I will cover Pal-GHK, one of the peptides I am going to be taking.

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Pal-GHK


PSL has recently started carrying peptides through the Europharmacy Line. I trust EP for all my other needs. I had never heard of Pal-GHK so I decided to do some research. I read through the body building forums about it and was intrigued, so I went to the medical studies for it and was blown away. Here are some snippets:

The aim of this paper is to bring attention to a compound with a long history of safe use in wound healing and antiaging skin care. The human tripeptide GHK was discovered in 1973 as an activity in human albumin that caused old human liver tissue to synthesize proteins like younger tissue. It has high affinity for copper ions and easily forms a copper complex or GHK-Cu. In addition, GHK possesses a plethora of other regenerative and protective actions including antioxidant, anti-inflammatory, and wound healing properties. Recent studies revealed its ability to up- and downregulate a large number of human genes including those that are critical for neuronal development and maintenance.


The human copper-binding tripeptide glycyl-L-histidyl-L-lysine (GHK) is a compound with a long history of safe use in wound healing and antiaging skin care. Since its discovery in 1973, almost four decades of extensive research have established its diverse beneficial actions in many organs and tissues including nervous tissue, skin, intestine, bone, and blood vessels. The molecule has a high affinity for Cu (II) and forms the chelate GHK-Cu. The GHK copper complex (or GHK-Cu) has been proven to exhibit antioxidant, anti-inflammatory, regenerative, and wound healing action.

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The Human Tripeptide GHK-Cu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health


WOW! Been used in the medical community since 1973? What else does the study say?

Inflammation and oxidative damage due to the overproduction of proinflammatory cytokines play an important role in the development of AD (Alzheimer's) and other neurodegenerative conditions [41]. In 2001 McCormack et al. established that GHK-Cu decreased proinflammatory cytokine TGF-beta in human fibroblast culture [42]. In 2003 Canapp et al. demonstrated that GHK-Cu improved healing of ischemic wounds and suppresses inflammation by lowering the level of acute-phase inflammatory cytokines such as TGF-beta and TNF-alpha [43].

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It might help prevent Alzheimer's and other neurodegenerative diseases.

From wound healing studies, it is known that GHK-Cu helps reestablish blood flow into damaged tissues through a mixture of three actions: angiogenesis (new blood-vessel formation), anticoagulation, and vasodilation. GHK-Cu increases the expression of basic fibroblast growth factor and vascular endothelial growth factor, both of which aid blood vessel formation [45]. In addition GHK-Cu's ability to stimulate synthesis of collagen and elastin is useful in restoring integrity of blood vessel walls.

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Helps new blood vessels grow, and strengthens existing ones, which helps wounds heal faster and helps prevent bruising.

Both Sensenbrenner et al. and Lindner et al. found that GHK stimulates the outgrowth of cultured nerves [48, 49]. Ahmed et al. established that nerve stubs placed in a collagen tube impregnated with GHK (used without copper) had an increased production of nerve growth factor and the neurotrophins NT-3 and NT-4 increased migration of cells into collagen tube and sped up the regeneration of nerve fibers. In addition, GHK also increased axon count and proliferation of the Schwann cells compared to the control group [50].

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Pal-GHK helps nerves repair themselves and helps new nerves grow in damaged areas.

First evidence that GHK-Cu may regulate an activity of certain genes came from wound healing and skin remodeling studies. By 1983, Pickart had established that GHK-Cu accelerates wound healing and contraction, improves the take of transplanted skin, and also possesses anti-inflammatory actions [53, 54].


Iorio et al. used a repository of transcriptional responses to compounds, the Connectivity Map (cMap) [60], and MANTRA software (http://mantra.tigem.it/) to explore networks of compounds producing similar transcriptional responses. GHK, as one of the compounds studied, increased mRNA production in 268 genes while suppressing 167 [61].
Also, Hong et al. used genome-wide profiling to identify genetic biomarkers (genetic signature) for metastasis-prone colorectal cancer as well as their perturbagens—substances that modulated their expression. GHK suppressed RNA production in 70% of 54 human genes overexpressed in patients with an aggressive metastatic form of colon cancer and was active at a low nontoxic 1 micromolar concentration [62].

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Gene mRNA suppression is effectively turning a gene off and increasing the mRNA production effectively makes it better at doing its job. They found Pal-GHK turns off some cancer causing genes while improving the function of skin repair and rejuvenation genes - which drastically helps the body grow new skin.

Epigenetic silencing of certain genes is currently considered the main reason for age-associated increase in tumorogenesis, oxidative stress, and inflammation. It is commonly accepted that human health is at its best until approximately the age of 20–25. It then begins to decline in later years. Recent genetic studies demonstrated accumulation of altered gene products in various tissues starting from the age of 20–25 [64]. In later decades of life, the genes produce less regenerative proteins but more inflammatory and oncogenic genes.


At present, it is not always possible to track gene effects to its protein product; however, we may conclude from all experimental data on GHK-Cu effects that the reversing of gene silencing by GHK has protective and health-promoting benefits.

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As we age, the genes that help us heal start to turn off (gene silencing). Pal-GHK not only stops this from happening, but actively restarts these genes!

The human tripeptide GHK has a long history of safe use in wound healing and skin care; it is naturally occurring, nontoxic, and is active at a very low nanomolar concentration. It readily forms complexes with copper, regulating its metabolism and improving its bioavailability. It possesses antioxidant, anti-inflammatory, and regenerative properties, improves circulation, supports stem cell functions, and promotes nerve outgrown and synthesis of neurotrophic factors. Recent studies demonstrated its ability to regulate a large number of human genes. At 1 micromolar it was able to suppress 70% of genes overexpressed in metastatic colon cancer. It upregulates p63 and integrins in epidermal stem cells, increases collagen, glycosaminoglycans, and decorin expression. Our studies with the Broad Institute's Connectivity Map revealed its ability to regulate a large number of human genes including those that are involved in nervous system physiology, development, and maintenance.

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Topical application of Pal-GHK was tested to see if it grew hair, and it was found to grow hair as well as minoxidil 5% does. No study has been done yet to see if SubQ will also grow hair, but I am going to take pictures and find out.
https://www.researchgate.net/publication/14873448_Chemical_Agents_and_Peptides_Affect_Hair_Growth


TL, DR:
Pal-GHK is a wonder peptide that has been in use since 1973. It is a great anti-oxidant, helps prevent Alzheimer's and other age related mental problems, helps new blood vessels grow in damaged areas (which helps healing), helps nerves repair themselves and actually helps new nerves to grow, improves the actions of genes that help in healing while suppressing genes that help cause cancer, turns on the healing genes that went silent as we age, and helps skin grown and rejuvenate. It might even help you regrow your hair as if you are taking minoxidil 5%.

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Here it is, in all its glory!

I am also going to be running TB500 with the Pal-GHK. My boss' boss at PSL heard about my plight and that I was going to run Pal-GHK for healing. Since TB500 and Pal-GHK both help with healing in very different ways, they work great together. PSL is going to send me a bunch of TB500 to run for free! I have seen PSL do this for people from time to time, but never expected to be the recipient of it myself. Quite nice!



TB500 (aka TB4, aka Thymosin Beta)


TB500, which is a form of TB4. TB4 is made by the body in response to inflammation (and for other things). Since it is obvious it has to do with healing in some way, medical science has been very interested in it and creating synthetic versions of it. Since the body does a lot of things, we cannot just blindly say TB4 helps heal you, so studies were done. Lots and lots of them. Here are a few that I found to be good.

Promoting effects of thymosin β4 on granulation tissue and new bone formation after tooth extraction in rats.


OBJECTIVES:
The aim of this study was to evaluate the effects of thymosin β4 (TB4) on wound healing after tooth extraction in rats.


STUDY DESIGN:
After extraction of the rats' mandibular first molar teeth, a synthetic partial peptide of TB4 was injected intraperitoneally at the time of extraction and every day thereafter for 6 days. Control subjects for the treatment received identical amounts of phosphate-buffered saline solution in the same manner. Histologic analysis, apoptosis assay, and reverse-transcription polymerase chain reaction were performed.


RESULTS:
The overall data showed that TB4 treatment suppressed apoptosis and inflammation; it accelerated the process of wound healing, including new bone formation.


CONCLUSIONS:
The findings demonstrated not only the usefulness of the TB4 partial peptide in wound healing of tooth extraction sockets, but also its potential application for bone regeneration and osteogenesis in bone and bone-related tissues.

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Promoting effects of thymosin β4 on granulation tissue and new bone formation after tooth extraction in rats. - PubMed - NCBI


This study shows it not only helps in healing wounds, but also helps with bone regeneration! VERY welcome news for someone who is about to have a chunk of bone removed.

Thymosin beta4 is cardioprotective after myocardial infarction.


Abstract
Heart disease is a leading cause of death in newborns and in adults. We have found that the G-actin-sequestering peptide thymosin beta4 promotes myocardial and endothelial cell migration in the embryonic heart and retains this property in postnatal cardiomyocytes. Survival of embryonic and postnatal cardiomyocytes in culture was also enhanced by thymosin beta4. We found that thymosin beta4 formed a functional complex with PINCH and integrin-linked kinase (ILK), resulting in activation of the survival kinase Akt/PKB, which was necessary for thymosin beta4's effects on cardiomyocytes. After coronary artery ligation in mice, thymosin beta4 treatment resulted in upregulation of ILK and Akt activity in the heart, enhanced early myocyte survival, and improved cardiac function. These findings suggest that thymosin beta4 promotes cardiomyocyte and endothelial migration, survival, and repair and may be a novel therapeutic target in the setting of acute myocardial damage.

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Thymosin beta4 is cardioprotective after myocardial infarction. - PubMed - NCBI


TB500 is great for repairing heat damage. If you take a maintenance dose of TB500 and have a heart attack (for example) your odds of survival are increased and your recovery time is decrased.

The healing properties of thymosin-beta4 have been described in different types of tissues, such as the skin and cornea, and more recently it has been shown that thymosin-beta4 facilitates cardiac repair after infarction by promoting cell migration and myocyte survival.

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Therapeutic potential of thymosin-beta4 and its derivative N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) in cardiac healing after infarction. - PubMed - NCBI


It helps the eyes and the skin to heal as well.

Peptide fragment of thymosin β4 increases hippocampal neurogenesis and facilitates spatial memory.


Abstract
Although several studies have suggested the neuroprotective effect of thymosin β4 (TB4), a major actin-sequestering protein, on the central nervous system, little is understood regarding the action of N-acetyl-serylaspartyl-lysyl-proline (Ac-SDKP), a peptide fragment of TB4 on brain function. Here, we examined neurogenesis-stimulative effect of Ac-SDKP. Intrahippocampal infusion of Ac-SDKP facilitated the generation of new neurons in the hippocampus. Ac-SDKP-treated mouse hippocampus showed an increase in β-catenin stability with reduction of glycogen synthase kinase-3β (GSK-3β) activity. Moreover, inhibition of vascular endothelial growth factor (VEGF) signaling blocked Ac-SDKP-facilitated neural proliferation. Subchronic intrahippocampal infusion of Ac-SDKP also increased spatial memory. Taken together, these data demonstrate that Ac-SDKP functions as a regulator of neural proliferation and indicate that Ac-SDKP may be a therapeutic candidate for diseases characterized by neuronal loss.

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Peptide fragment of thymosin β4 increases hippocampal neurogenesis and facilitates spatial memory. - PubMed - NCBI


As TB500 breaks down, one of the pieces it breaks into is Ac-SDKP. Ac-SDKP appears to help repair the brain.

Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.


CONCLUSION:
In conclusion, this study demonstrated, for the first time, that Tβ4 was down-regulated in ROS-stimulated PDLCs as well as Tβ4 activation exhibited anti-inflammatory effects and anti-osteoclastogenesis in vitro. Thus, Tβ4 activation might be a therapeutic target for inflammatory osteolytic disease, such as periodontitis.

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Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells. - PubMed - NCBI


TB500 reduces inflammation and promotes cell migration (bad cell removal, good cell replacement).

Thymosin beta-4 (Tβ4) is known to induce hair growth and hair follicle (HF) development; however, its mechanism of action is unknown.


Tβ4 appears to regulate P38/ERK/AKT signaling via its effect on VEGF expression, with a resultant effect on the speed of hair growth, the pattern of HFs and the number of hair shafts.

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http://www.ncbi.nlm.nih.gov/pubmed/26083021


Makes you not only grow thicker hair faster, but will actually create NEW hair follicles....which means MORE hair.

Therapeutic Benefit of Extended Thymosin β4 Treatment Is Independent of Blood Glucose Level in Mice with Diabetic Peripheral Neuropathy.


Abstract
Peripheral neuropathy is a chronic complication of diabetes mellitus...Tβ4 treatment did not significantly alter blood glucose levels. Treatment with Tβ4 significantly increased intraepidermal nerve fiber density. Furthermore, Tβ4 counteracted the diabetes-induced axon diameter and myelin thickness reductions and the g-ratio increase in sciatic nerve...Our data demonstrate that extended Tβ4 treatment ameliorates diabetic-induced axonal degeneration and demyelination, which likely contribute to therapeutic effect of Tβ4 on diabetic neuropathy.

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http://www.ncbi.nlm.nih.gov/pubmed/25945352


Apparently, nerve damage is something diabetics have to worry about. TB500 not only stops this from happening, but actively reverses the damage done to the sheaths around the nerves.






TL,DR


TB500 has been clinically shown to:


1. Rapidly heal skin wounds
2. Rapidly heal tissue damage (regardless of tissue type)
3. Repair damage done, and prevent future damage, to the protective sheaths the cover nerves
4. Rapidly recover from heart damage
5. Repair damaged brain cells
6. Regrow bones
7. Create new hair follicles.

DOSING


Pal-GHK has a very short half-life, so it should be injected 2 or 3 times a day for maximum results. Even one shot a day will help, but I am going to do 3 to get maximum benefits. It is recommended to do 200-300mcg in each injection. I am going on the high end of the recommendation and doing 333mcg simply because it made the math easy when I preloaded a bunch of slins today. Each bottle of Pal-GHK is 10mg, and each day I will be doing 3 shots of 333mcg, which means 1mg total a day. Therefor each bottle will last 10 days. I have 10 bottles...so I have 100 days worth. There is no recommended maintenance dose to take, and I suspect it would not be helpful to take Pal-GHK all the time, due to its very short half-life. It is a "use it when you need it" peptide.


TB500 does not have a short half-life, so only 3 shots a week are needed, with each shot being 2mg. Each bottle is 2mg, so that makes 3 bottles a week for a total of 4 weeks, so 12 bottles total. It is recommended to take a maintenance dose of 1 or 2 shots a month of 2mg each after the blast of TB500 is done. I plan on doing that if I can afford it.


I am also taking 2IUs a day of Eurotropin HGH. I dropped it down from 4IUs a day to make sure I do not have any false carpal tunnel symptoms from the HGH.


I am really hoping the synergistic effects of these three wonderful items will drastically shorten my recovery time.



So in short, the dosing is:


Pal-GHK: 3 shots a day of 333mcg each for as long as desired.
TB500: 3 shots a week of 2mg each for 4 weeks, then a maintenance dose of 2 shots a month of 2mg each.
HGH: 2IU a day, forever (or at least 8 months to get the full benefits of it - go as long as money will allow).

Great post. Thank you for referencing studies to support your point also! I found this really interesting and will be passing on to some clients that struggle with some similar issues as yours.

What a detailed write up. I look forward to watching for your full recovery post surgery. Godspeed brother!


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TheShadow said:

Great post. Thank you for referencing studies to support your point also! I found this really interesting and will be passing on to some clients that struggle with some similar issues as yours.

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Bro-science has its place, but I prefer Pub Med. I am one of the few who actually ENJOYS reading them.

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I am out of surgery and doing quite well. I am an optimist at heart and even I am surprised by how well I am doing.

At least 4 different nurses (or assistant nurses) and one doctor (the aide to my surgeon) all told me I have been recovering faster than anyone they have seen so far. They were surprised to see me moving about without ANY issues a mere 3 hours after having a vertebrae removed from my neck. I have full range of motion, except for whatever the neck brace stops me from doing (and I am not trying to override it - I was a good, clean healing!).


At first I thought it was just that 3J, my personal trainer, has whipped me into a pretty good shape (and together we will get me even better after I am healed), but thinking about it now that I am not hopped up on Oxycodone, I realize it must be the HGH I have been taking for the last several months. I had gone up as high as 4IU, but two weeks before the surgery I dropped it down to 2IU to make sure there were no false carpal tunnel effects or anything caused by the HGH. I know 2IU does not give me any of those things, so I can be safe at that point.


I am sure the HGH has already kicked the healing up a notch. I took 2 doses of Pal-GHK yesterday and today I am on the normal 3 doses a day routine. I should have the TB500 in hand in 2 weeks or so, just in time to get the neck brace removed.


I am in GREAT spirits! Now that the pain is almost completely gone, I must be feeling the improved sense of well being everyone talks about HGH and Proviron giving them. Not surprisingly, having two bone spurs pressed tightly against my spinal cord cause a pain that even they could not reduce. Before surgery, my neck pain was a 1, my right shoulder a 1, my left fingers a 1, my right fingers an 8 and my right wrist a 9 on the 0-10 pain scale. Now, everything is a 1 except my wrist and fingers. My left fingers are a 2, my right fingers a 4, and my wrist a 0!!! NO PAIN IN MY WRIST AT ALL!!!!!!!


I was told the swelling in my neck is causing the pain in the fingers and neck and that it will slowly go away as the swelling goes down.


I am eager to see my surgeon's face in 2 weeks when he removes the neck collar and I have recovered a TON more than he would have expected. I am almost tempted to tell him why, since he is a bodybuilder himself...but I still feel strange about telling doctors about such things.


I am now off to watch my recording of Agents of Shield.

DAY 5
Holy crap, where did the last few days go? I have slept more in the last few days than I have slept in the last few WEEKS leading up to surgery!


Due to being, essentially sedentary, my personal trainer has dropped me to a 2000 cal per day diet. Here is my current daily workout routine:



I have a set of exercises I have to do twice a day. I added to it some to complete the whole body workout. Every exercise is performed 30 times, twice a day.



Sitting:
Rounded Foot Lifts - Start with foot on heel and roll it forward onto toes, rounding the foot as it progresses forward.
Shoulder Circles backwards then forwards
Centerline Flexes - you know that "hinge" in your rib cage where you can bend it and make the ribs concave, then bend the other way and make the back concave? Do each of them 30 times.
Bicep Curls - 3 pounds
Tricep Curls - 3 pounds



Standing:
Calf Raises
Ballet Movements - With all weight on left leg, move right leg to the side and tap the toe lightly, then bring back to center. Move the right leg backwards and tap the toe lightly, bring back to center. Do each leg 30 times.
Skull Crushers - 3 pounds



0.4 mile brisk walk, twice a day.

Bro, this is great info I love reading the studies as well. Especially seeing how I'm going through some tendon/ligament problems right now and will meet with the specialist tomorrow doing as much research as I can so I go into my appointment as educated as possible.


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snaff05 said:

Bro, this is great info I love reading the studies as well. Especially seeing how I'm going through some tendon/ligament problems right now and will meet with the specialist tomorrow doing as much research as I can so I go into my appointment as educated as possible.

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Thanks! I enjoy reading the studies, I just have to make sure I keep I mind that the results of a study are only as good as the setup of the study...so a poorly crafted study will provide poor results. These all seemed to be done well, so I am hopeful!

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Day 6


For the last 2 days, I have been sleeping without my neck brace on. I normally sleep on my back and I normally do not toss and turn, so I felt safe doing it as an experiment. The sleep is MUCH better without the collar, but both mornings I woke up more sore than the day before, so I have ended that experiment. Not yet time...I should have waited longer. I will try again in 3 more days and see if there is any improvement.


I can only sit for 1 hour before I start to suffer neck pain...they were right when they forbade me from doing any extended sitting or standing! I was also approved for Short Term Disability for 1 month - but if I am cleared to work sooner than that I am to call them and they will end it at that point.


I am taking the pain drugs sparingly - as in only when I am actually in great pain (6 or higher on the 0-10 pain scale). At 6 to 7, I take one pill and at 8 to 10 I take 2 pills. I am rarely at a 6 or higher any more. I was told it would take a few weeks for the swelling to go down and the pain in my fingers and wrist to start going away, but the pain in my wrist is a 0 almost all the time and my left fingers are never higher than a 4 (and almost always a 2). My right fingers are usually a 4 and sometimes go up to an 8 if I am being stupid (ie, using them for too long at one shot). As a comparison, my right wrist was a 9 before surgery (if I moved it at all!) and my right fingers were an 8 any time I even lightly touched them...and were a 6 if I did not touch them. So the improvement has been HUGE so far. I have only felt like crying from the pain once since surgery, it was a daily feeling before.


The sucky part about the Pal-GHK is that you do not feel it doing anything in your system. HGH has many effects you can see and feel so you know it is doing something, but Pal-GHK does not. The only thing I have to see if it is working is to compare my recovery to a normal recovery curve. So far, I am twice as recovered as I should be. I base this off what the surgeon's assistant said and how all the nurses acted towards me. I also base it off the amount of pain I have on a regular basis. Since I am not yet supposed to feel much relief (due to the swelling) and I feel a LOT of relief. The wrist pain was supposed to go away instantly, and it did, so the surgery did its job. Now to wait for the swelling to go away.


Pal-GHK helps with swelling and so does TB500 (which is in transit).


I am a little sad...due to the pain I messed up my last order and forgot to add Proviron to it. I just ran out. Luckily, there is a sale on proviron at PSL, so I can buy it cheaper. I can save money but I would rather have not ran out. I was starting to feel the improved sense of well being it grants now that most of the pain is gone. I should not have been surprised that large amounts of pain crush a person's sense of well being...but I am nonetheless.


I almost forgot to add that I am taking the neck brace off every other hour for 15 minutes each day. I take very great care not to do anything stupid while it is off. I just do not want any neck muscle atrophy to hinder recovery when it is finally removed for good.


I also increased my max weight moved - almost DOUBLED it! I am now at 5 pounds (I am forbidden from doing anything higher until my neck brace is removed). Look out world, a beast is being born!!!

Day 11


Other than overdoing it shopping with the wife at Home Depot and Target, things have been going good. I am having a lot of trouble sleeping due to the neck brace, but that comes off on Thursday morning. It stabs into the back of my head and chokes me no matter what angle I sleep at. Other than the lack of sleep and associated issues that brings, I feel great and am looking forward to moving up to 10 pounds weight lifting on Thursday.

I hit the gym today for the first time in weeks. I have always been cleared to do any kind of leg exercises, provided they do not impact the back at all, so no squats or such. I did some pretty heavy leg work, used isolation machines to work my triceps and biceps without moving the shoulders or back, and even did 20 minutes on the elliptical, keeping the heart rate to about 125bpm. I have been told I can do light cardio and so I kept it light. They want me to keep increasing my time and speed that I do cardio, slowly of course.


I feel the most alive I have felt in a long time. I did not realize just how much I enjoyed working out! It had started to become a routine, and maybe a little bit of drudgery too. Not any more, this has shown me that I really DO LOVE working out and that it makes me feel truly alive.


I cannot wait to be fully cleared to start slowly ramping up my weights again. In 2 days the neck brace comes off and I will be cleared for 10 pounds of lifting. Not too long after that I should be cleared for unlimited lifting, based on listening to my body. EVERYONE in our lifestyle (who is not an idiot) already listens to their body. Sure, sometimes we ignore it, but we listen. I plan on not ignoring it, too much at stake. But the future looks bright and promising. In another year I will be all but unrecognizable, that is how much I am going to change my body. 3J (from www.3jsdiet.com), my trainer and dietician, will keep me on the straight and narrow and prevent me from being stupid with it, of course, and together we will turn me into someone women half my age look at with desire.

Why not just come out and post the studies. You're lying your ass off to sell a product. Just sell the product. Enough with the bullshit

TheOldJJdigs said:

Why not just come out and post the studies. You're lying your ass off to sell a product. Just sell the product. Enough with the bullshit

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I posted the studies at the start of the thread. I even linked to them on pubmed and such, did you somehow miss them? You can find them HERE in posts 1 and 2, with dosing in post 3.

5-8-16


This past Thursday they removed my neck brace. I slept most of Thursday away...the sleep in the neck brace was terrible. The neck brace would both cut into the back of my head AND choke me from the front. They did a brief cardio assessment on me while I was there, to see how much cardio they would release me to do. They said my rapid recovery at the hospital is why they were doing the test and that they usually do not even think about clearing someone for full cardio after only two weeks. I had been following their self PT recommendations of adding 5 minutes a day to my walk...to a point. Once I reached an hour a day, twice a day, of a brisk walk I did not want to make it any longer! I did treadmill work for them - not pushing too terribly hard, but not being light about it either. When I hit 6 mph they told me not to go any faster. My heart rate rose to 140bpm and I was not in any pain, so they told me to drop to a slow walk to cool down and within a minute my heart rate was down to 115bpm. They cleared me for full cardio.


I also asked if I was cleared for full weight isolation exercises - any exercise where the muscle is isolated by a machine and my back is not in use at all, such as a tricep or bicep machine. They said yes, provided I start light and listen to my body. I have been doing full body workouts, with cardio, since Friday and slowly raising my weights in the ones I do. So far, so good!


Here is the MRI view that showed them I had bone spurs which were the root of my issues. The surgeon's viewer was in full color and supremely amazing, my viewer sucks but at least it works. His actually showed the trauma (via color changes) to the spinal cord that the bone spur was causing.





I received my care package from PSL. As I said earlier, they knew of my plight and sent me some stuff to help out with it, specifically a 3 month run of TB500! I took one shot so far and my next one is later on today. Doing the 2mg each shot, twice a week regimen. Along with the TB500, they sent me some Eurogil HCG, PT141, and Cialis. I will be testing those items out separately and put up posts on them.


A pic of the TB500 for you all!





I will update as I go along.

Saw my surgeon today and he said I am recovering very quickly. He is still going to follow the standard rules about weights and such, he told me, since the neck is important.

My fingers are still numb - pins and needles type of thing when I use them, but far less than before the surgery. My right wrist hurts like the dickens when I move the thumb in certain angles. Doc told me this is all due to swelling and it would take an additional 3 to 4 months for it to go away. A long time, but now I have a measure against which to check the healing power of the peptides. If the pain is gone in 2 months, then they drastically increased the healing time.

We will see, stay tuned!

One thing I CAN say is that pinning three times a day, every day, is getting a bit old. Sure, it is SubQ baby pins, but still...

Except for last night, I have had great sleep for the last week. I have slept 6 hours straight, waking up to pee usually, then going back to bed for another 2 to 3 hours. It has been a LONG time since I have had such good sleep!

I saw my surgeon today and he said I am healing very nicely, he said I am healed further than he would have expected and said I could double my weight lifted (per arm) to 40 pounds. That is more like it! I am going to keep doing isoluation exercise for now until the swelling is down more. Slow and steady so I do not have to get it redone. My surgeon said he would make it very painful for me if he had to redo all his fine work.


Here are my weights moved and what I do during my recovery. I do everything but legs every day and do legs on Thursdays.


Chest
Flat Bench Press: 15, 4, 6, 8, 20 - 130, 160, 140, 130, 80
Flat Bench Flys: 20, 20, 20 - 20, 20, 17.5


Back
Narrow Grip Rows: 15, 4, 6, 8, 20 - 120, 155, 135, 115, 65


Shoulders (numbers are per arm - limited by my doctor)
Military Press: 15, 4, 6, 8, 20 - 10 for each
Side Lateral Raises: 15, 4, 6, 8, 20 - 10 for each
Front Lateral Raises: 15, 4, 6, 8, 20 - 10 for each
Shrugs: 20, 15, 20 - 10 for each


Legs
Incline Leg Press: 15, 4, 6, 8 - 480, 710, 660, 570
Leg Extensions: 15, 4, 6, 8 - 175, 240, 195, 180
Leg Curls: 15, 4, 6, 8 - 145, 190, 160, 145
Calf Raises (done on a stepper to increase drop distance): 20, 20, 20 - Body Weight +45


Arms
Machine Bicep Curls (one arm at a time): 10 reps at 80, drop 10 pounds (one plate) and do 10 more reps, continue until at lightest weight for 20 reps
Machine Tricep (one arm at a time): 10 reps at 55, drop 10 pounds (one plate) and do 10 more reps, continue until at lightest weight for 20 reps

It has been a while since I posted an update - but I am happy to proclaim I am up to 65 pounds on my single arm tricep machine press down! Before the surgery, my right tricep would literally turn off if I tried to push anything over 40 pounds. Not struggle to push it as if it were 1000 pounds, but literally not even try to push, no engagement of the muscle.


Healing is going nicely!!!! I have another appointment with my surgeon in 6 more weeks and hopefully he will fully release me for unlimited weight. We shall see.

Any signs that the nerve regenerative effects of the peptides are working? Or do you think it's mainly just the hgh working to heal you? Also have you noticed any thickening or new growth of hair?

Guapo said:

Any signs that the nerve regenerative effects of the peptides are working? Or do you think it's mainly just the hgh working to heal you? Also have you noticed any thickening or new growth of hair?

Click to expand...

I have been taking pictures (of my balding spot) and will post them soon. I wanted a good before, middle of the run, and after picture and I have all three. Thanks for reminding me to post them!

As or nerve regeneration, I am proud to post this new update:

I can do push-ups again!!!! I have been unable to do a single push-up since January. I tried to do them a week ago and still could not lift myself up off the ground - my right tricep simply would not engage (due to the nerve damage caused by the bone spurs). Yesterday I tried to do them and was easily able to do 10 push-ups without any issues at all!!

I cannot say if it was the HGH or the Pal-GHK that was the big help in the nerve department, but since Pal-GHK is supposed to help regenerate nerves, I will give credit to it. Just be prepared to pin A LOT to have it do is magic.

That is so good to know! I have been having the same issue but with my calves. They just won't engage, and haven't for 7 years ever since I broke my back and crushed my spinal cord 75% of the way. Now they are so small from the atrophy. This has made it impossible to simply reach forward to shake someone's hand without either stabilizing myself, or falling forward into them. So embarrassing. If this actually works, I'm gonna be in debt to you for opening my eyes to this. Thank you. And I am glad to hear your results have been great! Good luck brother.

I'm in to see this as well; great write up bro.

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