Im into 5weeks 600mg test cyp and 400mg primo from H&B. I noticed last Saturday waking up fatigued, bones ache, not holding a lot of water and weights feel heavy and internal tremors. I’m going to run bloods but it takes 2+ weeks for hormone panel to come back. I upped my test to 700mg and dropped primo to 350mg and ordered hcg. Do you think I crashed e2 with that initial dose. Never once have I crashed e2 with primo, but I never ran H&b primo.


Well, a friend I support started last year his first cycle, it was 100mg Primo and 400mg Test. After 4 Weeks he pulled blood, and had the same issue, just on 100mg Primo is E2 dropped to 5!!! THat's insane! There are people who react different on Primo, even low dose.......myself too. I don't have this issue on mast. -But I wouldn't change everything now like theother said, check bloodwork and adjust then what is needed.