GLP-1's 4 LIFE!!

[Bolan]

Yes, weight regain is highly likely after stopping GLP-1 medications like Wegovy or Ozempic. Research shows most people regain the majority of their lost weight, often within 1.7 to 2 years, because the appetite-suppressing effects wear off. Studies indicate that 82% of users regain 25% or more of their lost weight within a year of stopping.

Key Findings on GLP-1 Weight Regain

• Rapid Initial Regain: Weight regain often happens quickly, averaging 0.4 kg (almost 1 lb) per month, which is faster than conventional diet-induced weight regain.
• Physiological Response: GLP-1s change metabolic set points; once removed, the body typically reverts to its former state.
• Cardiometabolic Impact: Heart health benefits (like improved blood pressure and cholesterol) often diminish as the weight returns.
  

How to Minimize Weight Regain

• Tapering Dosage: Working with a doctor to gradually reduce the medication rather than stopping abruptly can help minimize sudden weight spikes.
• Lifestyle Changes: Combining medication with behavioral changes, such as a high-protein diet and consistent exercise, is crucial for sustaining weight loss.
• Long-Term Strategy: Many people require a maintenance dose of the drug or long-term behavioral support to keep the weight off.

 

[grock23]

Also, people that are not incorporating resistance training into their GLP 1 course tend to lose a great deal of muscle, which is gained back in fat lbs when the drug is stopped.

 

[Nood]

So people who are lazy and fat stay lazy and fat?

 

[Hughmangoes]

People who don't workout or eat protein lose all their muscle with the weight and end up with like 1200-1500 maintenance tdee. Of course they're going to gain the weight back.

 

[HAAM]

Typical Big Pharma-
“Here’s a solution to your problem” (that will create new problems) for us to create and sell you solutions for.

You could even blame lack of education on nutrition and fitness, but anyone who’s spoken to the general public, even including many gym goers, most people don’t want to learn, or put consistent effort into change.

 

[Bolan]

Typical Big Pharma-
“Here’s a solution to your problem” (that will create new problems) for us to create and sell you solutions for.

You could even blame lack of education on nutrition and fitness, but anyone who’s spoken to the general public, even including many gym goers, most people don’t want to learn, or put consistent effort into change.

Someone who gets it!!

 

[Jbswole40]

I know and have few people on glp1s,most or overweight, health problems etc,they like it.Its their choice. Dr,rx are expensive as f..
I myself dont and have never tried them.I most likely will never.

 

[Chemicalreaction]

I know and have few people on glp1s,most or overweight, health problems etc,they like it.Its their choice. Dr,rx are expensive as f..
I myself dont and have never tried them.I most likely will never.

For me personally I'm not a over weight person at all but glp 2 has helped me pretty much quit cigars completely I don't crave them anymore at all and I had a bad binge eating problem all my fault yes I know but now it's not an issue

 

[Bolan]

For me personally I'm not a over weight person at all but glp 2 has helped me pretty much quit cigars completely I don't crave them anymore at all and I had a bad binge eating problem all my fault yes I know but now it's not an issue

So when you come off GLP's will you start smoking stogies again?
Or is it GLP-1's 4 LIFE!

 

[Chemicalreaction]

So when you come off GLP's will you start smoking stogies again?
Or is it GLP-1's 4 LIFE!

Lol hell no I won't smoke again I smell that shit and get grossed out I'm

 

[Ryandenzy]

I use Reta being a former type 2 diabetic. Was a raging alcoholic for decades which caused that and many other issues I continue to deal with. Sobriety, diet and my lifestyle change got my A1C from 9.7 down to 5.3 which is good but wanted better including lipids. Reta has me at 5.0 now and lipids are better than when I was a teenager. I use it on a cut and bulk. I'm not sure if I ever will come off it totally. It's been amazing for my health.

 

[Jbswole40]

I use Reta being a former type 2 diabetic. Was a raging alcoholic for decades which caused that and many other issues I continue to deal with. Sobriety, diet and my lifestyle change got my A1C from 9.7 down to 5.3 which is good but wanted better including lipids. Reta has me at 5.0 now and lipids are better than when I was a teenager. I use it on a cut and bulk. I'm not sure if I ever will come off it totally. It's been amazing for my health.

Same here,alcohol caused many issues,the 1st month off my blood sugar was extremely low often throughout the day.I actually went hypo a few times.Its stable now.

 

[BFulforth]

I use Reta being a former type 2 diabetic. Was a raging alcoholic for decades which caused that and many other issues I continue to deal with. Sobriety, diet and my lifestyle change got my A1C from 9.7 down to 5.3 which is good but wanted better including lipids. Reta has me at 5.0 now and lipids are better than when I was a teenager. I use it on a cut and bulk. I'm not sure if I ever will come off it totally. It's been amazing for my health.

And Reta keeps so many bad cravings/noises away. Lots of benefits for mind and body.


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[Chemicalreaction]

Same here,alcohol caused many issues,the 1st month off my blood sugar was extremely low often throughout the day.I actually went hypo a few times.Its stable now.

Glad to see im not the one that has issues with drinking at one point in there life

 

[Jbswole40]

Glad to see im not the one that has issues with drinking at one point in there life

It had gotten extremely bad.

 

[rollin-tumblin]

Two very obvious things:

1. Majority of people who lose weight gain back a significant portion

2. Water is wet.

 

[TomJ]

I'll be using reta in some capacity at least intermittently for the whole foreseeable future

not for weight loss though, strictly because how profound of an effect it's had on my lipids and insulin sensitivity.

 

[GonadalGooner88]

Typical Big Pharma-
“Here’s a solution to your problem” (that will create new problems) for us to create and sell you solutions for.

You could even blame lack of education on nutrition and fitness, but anyone who’s spoken to the general public, even including many gym goers, most people don’t want to learn, or put consistent effort into change.

Hey bro, you think medical costs would be higher or lower if everyone was sub 25bmi vs averaging at 35bmi? The 25bmi group has most people on some glp1 i guess so there's that factor, but let's think for 2 seconds.

Moreover, who do you think developed your steroids? Huckleberry Cletus and his water powered tractor, or some glasses wearing PhD working for big pharma?

 

[HAAM]

Hey bro, you think medical costs would be higher or lower if everyone was sub 25bmi vs averaging at 35bmi? The 25bmi group has most people on some glp1 i guess so there's that factor, but let's think for 2 seconds.

Moreover, who do you think developed your steroids? Huckleberry Cletus and his water powered tractor, or some glasses wearing PhD working for big pharma?

Lol, did I hurt your feelings?

I didn’t say all things big pharma does is bad. I didn’t even say glps were bad. Personally, I'm a fan of Reta. No one needs to justify its use. I’d like to think most of us in here would use compounds like this intelligently. But we are not the general public. We already know how to eat, train, rest, cycle compounds when necessary, etc.

 

[S00Meaty]

Lol, did I hurt your feelings?

I didn’t say all things big pharma does is bad. I didn’t even say glps were bad. Personally, I'm a fan of Reta. No one needs to justify its use. I’d like to think most of us in here would use compounds like this intelligently. But we are not the general public. We already know how to eat, train, rest, cycle compounds when necessary, etc.

I don't think you hurt his feelings. I actually get both sides of what each of you say.

What irks me is the number of dumb fuck idiots on the forums always saying pharma is bad/evil and doctors are stupid, yet me, the juicing truck driver, plumber, mechanic, jobless, janitor etc... etc... I'm the guy that knows everything cuz I inject drugs and lift weights the bestest most smartest way. Look to me for your answers cuz I have all the correct ones.....fuck pharma and fuck doctors, who needs them.......

Call me dumb, but I'll go with facts and proven science backed by data and experience in the field from professionals vs some dipshit that thinks they are special cuz they take steroids and lift weights. The vast majority of us lift and juice, it doesn't make us special. Not many use their brains though or have a fucking clue what they spout off about.

Finally bro, don't take my saltiness and sarcasm as a dig at you. It isn't. I'm kind of burnt out seeing nonsense from a large number of fucking morons across the forums who think taking steroids and lifting makes them smart and an expert in everything in life.

 

[S00Meaty]

Yes, weight regain is highly likely after stopping GLP-1 medications like Wegovy or Ozempic. Research shows most people regain the majority of their lost weight, often within 1.7 to 2 years, because the appetite-suppressing effects wear off. Studies indicate that 82% of users regain 25% or more of their lost weight within a year of stopping.

Key Findings on GLP-1 Weight Regain

• Rapid Initial Regain: Weight regain often happens quickly, averaging 0.4 kg (almost 1 lb) per month, which is faster than conventional diet-induced weight regain.
• Physiological Response: GLP-1s change metabolic set points; once removed, the body typically reverts to its former state.
• Cardiometabolic Impact: Heart health benefits (like improved blood pressure and cholesterol) often diminish as the weight returns.

How to Minimize Weight Regain

• Tapering Dosage: Working with a doctor to gradually reduce the medication rather than stopping abruptly can help minimize sudden weight spikes.
• Lifestyle Changes: Combining medication with behavioral changes, such as a high-protein diet and consistent exercise, is crucial for sustaining weight loss.
• Long-Term Strategy: Many people require a maintenance dose of the drug or long-term behavioral support to keep the weight off.

So pretty much like all the weight loss drugs before it. If you aren't on for life, you aren't likely to keep the weight off. No way around making the life changes necessary to keep it off for good.

The risk here too that I hope many don't face is the possibility we see say 5 years or so down the road that there are serious consequences to using these drugs. It seems unimaginable to me though, but you never know.

The number of people that would be fucked would be mind boggling especially considering the pill versions of the drugs out now and those that are still to come.

A lot of people like reta and take it around the forums. I would say use caution with something that isn't even FDA approved yet. Shit even FDA approved doesn't mean a ton but its better than not being FDA approved. Of course UGL too, you have to trust that what you are getting really is reta....and yes, you even have to trust that your hplc testing source isn't compromised.

 

[McPriimate]

Reta is just a different flavor of “gear.” Steroids, etc don’t seem so dissimilar in that if you come off them you lose the benefits and there could be long term consequences, etc etc

Not saying one’s better or worse - quite the contrary. Saying they’re all PEDs, for different aspects of performance. Not many that you can take and have the benefits accrue for life even after stopping

I don’t really get the hate toward glp’s tbh and haven’t heard many arguments against them that couldn’t be aimed at steroids or PEDs in general (or lots of conventional meds). Not for everyone, for sure, but what drug is?


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[J.S.]

There just a tool in the tool box to me, pulled out whenever I need it. When I first used Ozempic years ago to lose, I did change everything about the way I ate.I knew I didn’t want to stay using for the rest of my life. I can do just fine with an intermittent fast , but sometimes I just want a little more or a little quicker results.

 

[HAAM]

I don't think you hurt his feelings. I actually get both sides of what each of you say.

What irks me is the number of dumb fuck idiots on the forums always saying pharma is bad/evil and doctors are stupid, yet me, the juicing truck driver, plumber, mechanic, jobless, janitor etc... etc... I'm the guy that knows everything cuz I inject drugs and lift weights the bestest most smartest way. Look to me for your answers cuz I have all the correct ones.....fuck pharma and fuck doctors, who needs them.......

Call me dumb, but I'll go with facts and proven science backed by data and experience in the field from professionals vs some dipshit that thinks they are special cuz they take steroids and lift weights. The vast majority of us lift and juice, it doesn't make us special. Not many use their brains though or have a fucking clue what they spout off about.

Finally bro, don't take my saltiness and sarcasm as a dig at you. It isn't. I'm kind of burnt out seeing nonsense from a large number of fucking morons across the forums who think taking steroids and lifting makes them smart and an expert in everything in life.

I guess I could clarify further. The “R&D” arm of big pharma has come out with some amazing products. No question. My issue is with the “sales and marketing” arm of big pharma.
Take Reta for example. Studies showing 1mg throughout a 48 week study having moderate, very acceptable, weight loss. 2mg showed more, 4mg even more, 8, and 12mg greater still. The fat loss increases, but not at the same rate as the increase in dosage. It doesn’t double, triple etc as the dose does. Why push 12, when 1 will work? $$$$$$$ that’s the side “R&D” has no say over. I get the science, but I’m not taking suggestions on dosing from the advertisers whose sole job is to maximize profits.

 

[McPriimate]

I guess I could clarify further. The “R&D” arm of big pharma has come out with some amazing products. No question. My issue is with the “sales and marketing” arm of big pharma.
Take Reta for example. Studies showing 1mg throughout a 48 week study having moderate, very acceptable, weight loss. 2mg showed more, 4mg even more, 8, and 12mg greater still. The fat loss increases, but not at the same rate as the increase in dosage. It doesn’t double, triple etc as the dose does. Why push 12, when 1 will work? $$$$$$$ that’s the side “R&D” has no say over. I get the science, but I’m not taking suggestions on dosing from the advertisers whose sole job is to maximize profits.

Fair enough on pharma, profit and the way incentives drive their behavior. Same time, a dose-response where more is more, but with diminishing returns is true of many if not most drugs. Nothing to do with the profit to pharma.

Where the system falls apart imo is with the docs prescribing the drugs (and where pharma is truly greedy in the way they influence prescribers - which is pretty much any way they can get away with, from bagels and free pens to dinners and even sponsored trips). Docs are supposed to be above all that and just do right by their patients (like prescribing only the dose the patient needs, not more or less), but study after study shows that even a free fucking pen influences their prescriptive practices.

Many academic hospitals now have strict rules on what pharma reps can and can’t do and what docs/NPs/PAs can and can’t accept, but it’s just so pervasive (although those restrictions are also why pharma now spends a gajillion dollars on direct to consumer ads). Docs could still prevent a lot of it but they’re also overworked and often just cave to patients’ requests whether it’s medically necessary or not

Of course, I realize I’m writing this on a site where we just about all take matters into our own hands and do a lot of stuff that’s not medically necessary, so it’s a tough soapbox to stand on for long

Whole medical system thing just sucks and is such a shame, but greed is pretty deep in our DNA I guess

Don’t get me started on the biggest problem - insurance companies


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[Bathman316]

Anyone's thoughts on Reta Not being / working for them? Last year 2025 was a full recomp, I changed everything from diet to training, hydration etc. I was fat 25%+bf now I'm much leaner at 225-230lbs, around 13-14%bf.. I was running 250test cyp, 5iu gh and 200maste for 4 months and it help tremendously ... I'm currently on a health phase of normal hrt 15mg test cyp ed, 2 iu gh ed.... I feel great except....

I started Reta 7 weeks ago (great source so I know it's legit) with hopes to get much leaner before I start trying to grow more. I may need to drop 15-20lbs to hit my goal "look" not a crazy amount... and I haven't seen much positives as far as bf reduction. I'm constantly backed up even though I take enough fiber and hydrate enough. I can barely shit, it does suppress my appetite but I make sure to get my macros in... my BG is actually higher in the am from the previous day of eating I believe because of the delayed gastric emptying...I purposely cut carbs off at lunch time so my BG isn't too high before bed or upon waking....it's frustrating because I see and hear everyone raving how well this works and here I am. Any thoughts or feedback would be great. Much respect good brothers.

 

[Bolan]

Anyone's thoughts on Reta Not being / working for them? Last year 2025 was a full recomp, I changed everything from diet to training, hydration etc. I was fat 25%+bf now I'm much leaner at 225-230lbs, around 13-14%bf.. I was running 250test cyp, 5iu gh and 200maste for 4 months and it help tremendously ... I'm currently on a health phase of normal hrt 15mg test cyp ed, 2 iu gh ed.... I feel great except....

I started Reta 7 weeks ago (great source so I know it's legit) with hopes to get much leaner before I start trying to grow more. I may need to drop 15-20lbs to hit my goal "look" not a crazy amount... and I haven't seen much positives as far as bf reduction. I'm constantly backed up even though I take enough fiber and hydrate enough. I can barely shit, it does suppress my appetite but I make sure to get my macros in... my BG is actually higher in the am from the previous day of eating I believe because of the delayed gastric emptying...I purposely cut carbs off at lunch time so my BG isn't too high before bed or upon waking....it's frustrating because I see and hear everyone raving how well this works and here I am. Any thoughts or feedback would be great. Much respect good brothers.

Its not for bodybuilders. You need to eat to grow, or even maintain muscle mass.... the majority of people on these drugs are not bodybuilders, but people who let themselves go for too long and decide to hit the gym, take GLP-1's and who are not necessarily into bodybuilding.

You dropped a tremendous amount of body fat weight doing what you were doing.... keep on that path!!!!!!!!!

I just couldn't imagine going to gym... busting ass to grow lean tissue, using AAS and not gaining shit because I cant EAT!

Food noise, its in your head!!!!! Be stubborn!!!

 

[Wiseguy]

I never used them but like any diet no matter how much you lose you will gain everything back if you go back to bad habits. Unfortunately, it is clear very few clean up their eating habits.

 

[HFO4]

There is literally one way, it’s a lifestyle change from unhealthy to healthy.

. Otherwise, you’ve started with a trend, a fad, it’s a one off…a diet, you will end up worse off than when you started.

 

[J.S.]

There is literally one way, it’s a lifestyle change from unhealthy to healthy.

. Otherwise, you’ve started with a trend, a fad, it’s a one off…a diet, you will end up worse off than when you started.

Absolutely! Lot of people (got a friend) think they’ll get on this and the weight will fall off and then business as usual, wrong! You’ll not only put it back on, it’s fast and more than what you had to begin with. I explained this to him and anyone I’ve talked to about using glp’s, they just don’t know .