Blood work results 4 weeks in

[SBG22]

Hello all,

First time post. Long time lurker.
42m. Been lifting for 10years. Eat very well. Worked with a coach for a while to learn how to eat properly before doing all this. I’m 5’6” and totally I’m 188. Up from 182 when I started. Still fairly lean.

I have been on TRT since sept 2024. During the summer I decided I wanted to do my first “cycle” after my next doc appointment. So I started 12/1. My TRT regiment was 120mg per week. Taking MTF. My pre bloodwork on 11/24 showed the following:
Test: 789 down from 904 on 10/10
Estrodial: 12.3 down from 18.4 on 10/10
Shbg 44.5 up from 43.5 on 10/10

First week I went from TRT dose to 220mgs the first week then week 2 till now I have been at 300mg. I am pinning daily 44mgs.
Got my bloods done on 12/24 to confirm the stuff was legit.
Test is 2159
Estrodial is 72
Shbg is 46

Would you consider the E2 “high” given that my test is that high? I don’t have any symptoms other than sleep being incredibly difficult. I was experiencing sleep issues prior to the blast. It’s only gotten a little worse. I have arimidex on hand if needed.


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How do you feel currently? My E2 gets low and it’s the worst.

 

[dontchaknow83]

Yesterday was pretty rough. Today is getting better. Im going to just go back to .25mg of arimedix. No issues then


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[bt1k]

Thanks! I don’t have any symptoms at the moment. In your opinion is it worth just waiting it out till I experience symptoms?


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I know this is old but not being able to sleep was your symptom of High E2 Lol.

 

[dontchaknow83]

I know this is old but not being able to sleep was your symptom of High E2 Lol.

I wasn’t sleeping when my e2 was at 18. So I don’t think that is totally accurate. Just got my bloods done again last week at 70mg of test per day and it came back at 38. Still not sleeping great. My cycle ends tomorrow so we’ll see how I adjust when I go back to TRT.


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[Glycomann]

I know this is old but not being able to sleep was your symptom of High E2 Lol.

Not sure about that. His androgens are 3-4x normal range. Androgens have a mild central nervous system stimulatory effect. At 3-4x normal levels you have some stimulation.

 

[Glycomann]

I wasn’t sleeping when my e2 was at 18. So I don’t think that is totally accurate. Just got my bloods done again last week at 70mg of test per day and it came back at 38. Still not sleeping great. My cycle ends tomorrow so we’ll see how I adjust when I go back to TRT.


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Lots of us have that issue on higher levels of androgen but at least in me it subsides on TRT. my trough on TRT is only 470 ng/dL so my androgen levels are well within normal range over the week. Plotting it our with a 7 day 1/2 life gives me an average over the week of about 670 ng/dL. The point is, if you want to get better sleep and the problem is related to increase central nervous system stimulation from androgens, getting your level in normal range over the week could solve the problem. I note that your levels may be a little high on your TRT dose as you come down from your blast.