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HGH pre-bed

KellogCrush said:
Well effect of blood glucose can be dose dependent yes, but what I said still remains true that total pancreatic load will be roughly the same no matter when taken.

Did you actually understand what I wrote? Does that make
Click to expand...
KellogCrush said:
Well effect of blood glucose can be dose dependent yes, but what I said still remains true that total pancreatic load will be roughly the same no matter when taken.

Did you actually understand what I wrote? Does that make sense to you?
Click to expand...
Its fine. I just need to do more research. Appreciate the help.
 
Just read thru whole thread..
All kinds of good stuff here man!!
@KellogCrush gonna be honest once I post this?
Gonna Google ur pancreatic load thing..
Because I don't understand..lol
But I want to..
 
Pancreatic load refers to the amount of work the pancreas must perform to produce enzymes for digestion and hormones (like insulin) for blood sugar regulation. A high pancreatic load indicates that the organ is working harder than usual, which can result from factors like excessive sugar consumption, or it can be a, and if left unmanaged, can lead to chronic inflammation or failure.
 
Hablooblah said:
Its fine. I just need to do more research. Appreciate the help.
Click to expand...
In a nutshell

The reason for gh injections causing a blood sugar rise is the way it shifts you to burning fat for fuel allowing more blood glucose to circulate.

Knowing this, we know it’ll raise regardless if taken with carbs or not. Taken with carbs will indeed likely cause a higher spike than in bg than if you didn’t take that gh with food, but assuming you take the gh regardless at some point in the day it all equals out. If you instead take it fasted for example, you’re having a blood glucose rise still and for that period bg wont be as low as it would’ve been had you taken it later with a meal.

Now does it make sense? With food = a higher peak in bg while without food = a higher bg during that fasted period that would’ve otherwise been lower if not taken the gh. So pancreatic workload across the day if both scenarios.
 
Meetketchup said:
I will respectfully go with the recent peer reviewed studies, discussions with Dr's and 25 years of examining bloodwork with all types of diets including carb timing over a google search. :)

@Hablooblah Simply do 2iu and get bloodwork done with the eating schedule you want. See the results and adjust accordingly. Do what works for you at that point. You are not wasting gh at 2iu taking in low to mid carbs. Relax and worry about more important things like really dialing in your diet and training.
Click to expand...
Best advice right here!
 
KellogCrush said:
Endogenous gh is suppressed by insulin. Exogenous is not. Pretty much your entire comment here is outdated myths from old forums.

You literally linked an article on boosting natural gh…
Click to expand...
That's why I Google shit. For you guys... 2ius, fuck I wouldn't worry about snorting a line of sugar before pinning. Its the bigger doses you need to be careful about. This was my thinking... I train pros, Pros abuse HGH.
again READ the Google...lol No the article I copy n pasted was about BB dosing.


For optimal bodybuilding results with HGH injections, it is generally recommended to avoid eating for 1–2 hours before and after administration, particularly at night. Eating, especially refined carbs and sugar, raises insulin, which can inhibit HGH effectiveness. Nighttime injections (before bed) are preferred to align with natural hormone production, avoiding the insulin resistance caused by daytime injections combined with meals.
 
Bolan said:
Eating, especially refined carbs and sugar, raises insulin, which can inhibit HGH effectiveness.
Click to expand...
Not when you inject it. I couldn’t care less if you train pros. Plenty of people whom I’d consider uninformed do. If you inject GH, it will work regardless. IGF production from exogenous gh is not shut down by carbs.

For FAT LOSS, yes lypolisis will occur more when insulin is lower. That doesn’t mean GH isn’t working, it just shifts substrate usage. Insulin is actually useful for recovery and anabolism, and alongside GH can actually be synergistic for this even more so. I’m sure as a pro coach you’ve heard of athletes utilize them together periworkout.

Also not sure if you purposefully misinterpreted this or you’re just slow but I’m talking about this article you linked Naturally Increasing the Human Growth Hormone | Aurora, IL Chiropractor | Quality Care Chiropractic

Next time you do your google “research” specificy exogenous GH maybe look at some actual literature instead of these random bodybuilding articles. I mean you literally admitted to taking DNP in another thread because you read in an article it “cleans out your receptors”. I think if you actually put a little time and effort into researching this topic you’ll learn something.
 
KellogCrush said:
Not when you inject it. I couldn’t care less if you train pros. Plenty of people whom I’d consider uninformed do. If you inject GH, it will work regardless. IGF production from exogenous gh is not shut down by carbs.

For FAT LOSS, yes lypolisis will occur more when insulin is lower. That doesn’t mean GH isn’t working, it just shifts substrate usage. Insulin is actually useful for recovery and anabolism, and alongside GH can actually be synergistic for this even more so. I’m sure as a pro coach you’ve heard of athletes utilize them together periworkout.

Also not sure if you purposefully misinterpreted this or you’re just slow but I’m talking about this article you linked Naturally Increasing the Human Growth Hormone | Aurora, IL Chiropractor | Quality Care Chiropractic

Next time you do your google “research” specificy exogenous GH maybe look at some actual literature instead of these random bodybuilding articles. I mean you literally admitted to taking DNP in another thread because you read in an article it “cleans out your receptors”. I think if you actually put a little time and effort into researching this topic you’ll learn something.
Click to expand...
You do you....

People who know..know.

Keep listening to your online coach. RETARD!
 
KellogCrush said:
Not when you inject it. I couldn’t care less if you train pros. Plenty of people whom I’d consider uninformed do. If you inject GH, it will work regardless. IGF production from exogenous gh is not shut down by carbs.

For FAT LOSS, yes lypolisis will occur more when insulin is lower. That doesn’t mean GH isn’t working, it just shifts substrate usage. Insulin is actually useful for recovery and anabolism, and alongside GH can actually be synergistic for this even more so. I’m sure as a pro coach you’ve heard of athletes utilize them together periworkout.

Also not sure if you purposefully misinterpreted this or you’re just slow but I’m talking about this article you linked Naturally Increasing the Human Growth Hormone | Aurora, IL Chiropractor | Quality Care Chiropractic

Next time you do your google “research” specificy exogenous GH maybe look at some actual literature instead of these random bodybuilding articles. I mean you literally admitted to taking DNP in another thread because you read in an article it “cleans out your receptors”. I think if you actually put a little time and effort into researching this topic you’ll learn something.
Click to expand...
If I linked that study... yeah that's retard and I'm slow,,, but am quick to catch on to peoples ALT accts. ;)
 
Bolan said:
Thanks meetmustard !
Click to expand...
You refuse to believe more than one person things you’re wrong?… quite silly to think there’s something personal going on here just cause you don’t understand GH.

I have an account over on PM where I used to be more active. KingOfSushi. Feel free to dm me there if you want to see I’m another person. I have my physique posted there too.
 
KellogCrush said:
you don’t understand GH.
Click to expand...
EAA fuck Ive heard it all.

My mistake, I thought it was a bodybuilding dosage taken pre bed (10+iu's)
Not 2ius.

The way I'm looking at this thread is "bodybuilders" who take a larger
bolus Pre-bed should do it on 0 to LOW carbs to avoid IR, but I'm sure
your into Reta for that.
 
Bolan said:
EAA fuck Ive heard it all.

My mistake, I thought it was a bodybuilding dosage taken pre bed (10+iu's)
Not 2ius.

The way I'm looking at this thread is "bodybuilders" who take a larger
bolus Pre-bed should do it on 0 to LOW carbs to avoid IR, but I'm sure
your into Reta for that.
Click to expand...
I’m on 12iu. Everything I said still applies.

I’ve never used reta.

I’m nothing special but I think I’m a “bodybuilder”
https://imgur.com/a/ca6AzKW
View: https://imgur.com/a/ca6AzKW
 
SB Labs
JG1 said:
49yo male, 215lbs at about 10-12% BF. Running Test and Deca and just completed 17 weeks on Retatrutide. Diet is on point...300g carbs, 300g protein, 30g fat. Supplements: EPA/DHA (4g/day), Retatrutide, BPC-157, TB-500, GHK-CU.

I was considering the growth hormone secretagogues, but I may as well just use HGH, especially at my age.

Was thinking 4iu/day, pre-bed. I work Night Shift (2300-0730) and am in bed by 2pm, 5 days/week. I train at 8am, have my pwo shake at about 9:30am, then an hour later another 50g carbs and protein. I eat my pre-bed meal at 1pm which is Jasmine Rice, 96% GB, and chicken breast. How long before bed would I have to cut the carbs?
Click to expand...
Just take it before bed and don't worry about it.
 
Meetketchup said:
Remember GH doesn't spike until roughly 4 hours after injected. Lastly think of the guys in the off-season eating 4-6k calories a day with a ton of carbs yet they take gh pre bed and have high IGF levels. It takes hours for carbs to digest when digested with protein and or fats, so timing isn't a big factor. More important things to worry about. :)

Hope this helps and good luck!
Click to expand...
This 👆
Don’t over think HGH.
It works regardless of all the broscience timing.
My preference is taking it upon waking in a fasted state. I have food or a protein shake a half hour later. I don’t like taking HGH at night. My body is weird! I get energy when take it. 🤷‍♂️
 
JG1 said:
49yo male, 215lbs at about 10-12% BF. Running Test and Deca and just completed 17 weeks on Retatrutide. Diet is on point...300g carbs, 300g protein, 30g fat. Supplements: EPA/DHA (4g/day), Retatrutide, BPC-157, TB-500, GHK-CU.

I was considering the growth hormone secretagogues, but I may as well just use HGH, especially at my age.

Was thinking 4iu/day, pre-bed. I work Night Shift (2300-0730) and am in bed by 2pm, 5 days/week. I train at 8am, have my pwo shake at about 9:30am, then an hour later another 50g carbs and protein. I eat my pre-bed meal at 1pm which is Jasmine Rice, 96% GB, and chicken breast. How long before bed would I have to cut the carbs?
Click to expand...
But you didn't tell everyone how tall you are so the weirdos can jack-off.
 
KellogCrush said:
In a nutshell

The reason for gh injections causing a blood sugar rise is the way it shifts you to burning fat for fuel allowing more blood glucose to circulate.

Knowing this, we know it’ll raise regardless if taken with carbs or not. Taken with carbs will indeed likely cause a higher spike than in bg than if you didn’t take that gh with food, but assuming you take the gh regardless at some point in the day it all equals out. If you instead take it fasted for example, you’re having a blood glucose rise still and for that period bg wont be as low as it would’ve been had you taken it later with a meal.

Now does it make sense? With food = a higher peak in bg while without food = a higher bg during that fasted period that would’ve otherwise been lower if not taken the gh. So pancreatic workload across the day if both scenarios.
Click to expand...

Bolan said:
That's why I Google shit. For you guys... 2ius, fuck I wouldn't worry about snorting a line of sugar before pinning. Its the bigger doses you need to be careful about. This was my thinking... I train pros, Pros abuse HGH.
again READ the Google...lol No the article I copy n pasted was about BB dosing.


For optimal bodybuilding results with HGH injections, it is generally recommended to avoid eating for 1–2 hours before and after administration, particularly at night. Eating, especially refined carbs and sugar, raises insulin, which can inhibit HGH effectiveness. Nighttime injections (before bed) are preferred to align with natural hormone production, avoiding the insulin resistance caused by daytime injections combined with
Click to expand...

Bolan said:
That's why I Google shit. For you guys... 2ius, fuck I wouldn't worry about snorting a line of sugar before pinning. Its the bigger doses you need to be careful about. This was my thinking... I train pros, Pros abuse HGH.
again READ the Google...lol No the article I copy n pasted was about BB dosing.


For optimal bodybuilding results with HGH injections, it is generally recommended to avoid eating for 1–2 hours before and after administration, particularly at night. Eating, especially refined carbs and sugar, raises insulin, which can inhibit HGH effectiveness. Nighttime injections (before bed) are preferred to align with natural hormone production, avoiding the insulin resistance caused by daytime injections combined with
Click to expand...
Bolan said:
Look good for a classic guy.!! keep training hard!!
Click to expand...

JJB1 said:
This 👆
Don’t over think HGH.
It works regardless of all the broscience timing.
My preference is taking it upon waking in a fasted state. I have food or a protein shake a half hour later. I don’t like taking HGH at night. My body is weird! I get energy when take it. 🤷‍♂️
Click to expand...
Im kind of the same way...I heard it helped sleep but i think its making sleep difficult. Maybe ill try switching to fasted morning injections
 
Hablooblah said:
Im kind of the same way...I heard it helped sleep but i think its making sleep difficult. Maybe ill try switching to fasted morning injections
Click to expand...
I’ve seen posts where guys have said the same thing. I’m the opposite. It helps me sleep, especially taking it with the peptide DSIP and a serving of taurine and 5mgs of melatonin. I have sleep issues due to PTSD/anxiety disorder so when I take GH with the above listed supps it helps me go back to sleep when I wake up between 2:30 and 4 am with my mind racing or fucked up memories and dreams.
 
KellogCrush said:
Endogenous gh is suppressed by insulin. Exogenous is not. Pretty much your entire comment here is outdated myths from old forums.

You literally linked an article on boosting natural gh…
Click to expand...
What I read in few sources (including chatgpt) state insulin blunts GH, independent of the source - injected GH is impacted as well.
 
calf10 said:
What I read in few sources (including chatgpt) state insulin blunts GH, independent of the source - injected GH is impacted as well.
Click to expand...
Always ask for sources with ChatGPT. For example..

Short answer: carbohydrates (via insulin) suppress endogenous (natural) GH secretion from the pituitary, but they do NOT meaningfully blunt the biological action of exogenous (injected) growth hormone. This is the key distinction that bodybuilding forums often miss.
  1. Insulin/carbs suppress endogenous GH (this part is true) Veldhuis et al., 2005 – Endocrine Reviews
“Regulation of growth hormone secretion”

Hyperglycemia and hyperinsulinemia markedly suppress spontaneous and stimulated GH secretion. This applies only to pituitary GH release.
Ho et al., 1988 – Journal of Clinical Endocrinology & Metabolism
“Effects of glucose and insulin on GH secretion”
Oral glucose reliably suppresses GH secretion and is the basis of the oral glucose tolerance test used for acromegaly diagnosis.
  1. Insulin does NOT block exogenous GH receptor signaling or IGF-1 production

Leung et al., 2004 – Journal of Clinical Endocrinology & Metabolism
“Insulin regulation of growth hormone receptor signaling”
Insulin does not inhibit GH receptor activation or downstream STAT5 signaling in the presence of circulating GH.

Yakar et al., 1999 – Proceedings of the National Academy of Sciences (PNAS)
“Circulating IGF-1 is directly regulated by GH receptor activation”
Hepatic IGF-1 production depends on GH receptor activation and is independent of insulin levels within normal physiological ranges.
  1. Insulin is permissive (supportive), not antagonistic, to GH/IGF-1 anabolism
Thissen et al., 1994 – Endocrine Reviews
“Nutritional regulation of the insulin-like growth factors”
Insulin is permissive for IGF-1 action and enhances anabolic effects in skeletal muscle.
  1. Why fasted GH can favor fat loss (but is not required for GH to work)
Møller et al., 1990 – Metabolism

“Growth hormone and lipid metabolism”
pubmed.ncbi.nlm.nih.gov

Placental transfer of flecainide - PubMed

Placental transfer of flecainide
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
GH-stimulated lipolysis is reduced in the presence of hyperinsulinemia. This affects fat mobilization, not GH efficacy or IGF-1 production.

Bottom line:
Carbs and insulin suppress natural GH secretion, but they do not “turn off” injected GH. Exogenous GH works regardless of insulin levels. Eating carbs near GH injections may reduce acute fat burning, but it does not negate GH’s anabolic or IGF-1–mediated effects.
 
KellogCrush said:
Always ask for sources with ChatGPT. For example..

Short answer: carbohydrates (via insulin) suppress endogenous (natural) GH secretion from the pituitary, but they do NOT meaningfully blunt the biological action of exogenous (injected) growth hormone. This is the key distinction that bodybuilding forums often miss.
  1. Insulin/carbs suppress endogenous GH (this part is true) Veldhuis et al., 2005 – Endocrine Reviews
“Regulation of growth hormone secretion”

Hyperglycemia and hyperinsulinemia markedly suppress spontaneous and stimulated GH secretion. This applies only to pituitary GH release.
Ho et al., 1988 – Journal of Clinical Endocrinology & Metabolism
“Effects of glucose and insulin on GH secretion”
Oral glucose reliably suppresses GH secretion and is the basis of the oral glucose tolerance test used for acromegaly diagnosis.
  1. Insulin does NOT block exogenous GH receptor signaling or IGF-1 production

Leung et al., 2004 – Journal of Clinical Endocrinology & Metabolism
“Insulin regulation of growth hormone receptor signaling”
Insulin does not inhibit GH receptor activation or downstream STAT5 signaling in the presence of circulating GH.

Yakar et al., 1999 – Proceedings of the National Academy of Sciences (PNAS)
“Circulating IGF-1 is directly regulated by GH receptor activation”
Hepatic IGF-1 production depends on GH receptor activation and is independent of insulin levels within normal physiological ranges.
  1. Insulin is permissive (supportive), not antagonistic, to GH/IGF-1 anabolism
Thissen et al., 1994 – Endocrine Reviews
“Nutritional regulation of the insulin-like growth factors”
Insulin is permissive for IGF-1 action and enhances anabolic effects in skeletal muscle.
  1. Why fasted GH can favor fat loss (but is not required for GH to work)
Møller et al., 1990 – Metabolism

“Growth hormone and lipid metabolism”
pubmed.ncbi.nlm.nih.gov

Placental transfer of flecainide - PubMed

Placental transfer of flecainide
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
GH-stimulated lipolysis is reduced in the presence of hyperinsulinemia. This affects fat mobilization, not GH efficacy or IGF-1 production.

Bottom line:
Carbs and insulin suppress natural GH secretion, but they do not “turn off” injected GH. Exogenous GH works regardless of insulin levels. Eating carbs near GH injections may reduce acute fat burning, but it does not negate GH’s anabolic or IGF-1–mediated effects.
Click to expand...
Thanks for the links, much appreciated. Looks like I need access to the websites.
 

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