Very complicated subject. I don't have long so I almost didn't post. In short, several studies have shown GH does not raise the incidence of leukemia in normal patients with no high risk factors. It has tenatively been shown to increase the risk in persons with existing high risk factors for the disease. This is not surprising given its properties. Also, muddying the waters further, most of the studies are with kids, sadly, as we must remember a great deal of the lit/efforts regarding GH published is for ages 0-15.
To be brief for the OP, because it is important and this is a case where board makers and members should feel proud bc you are giving him vital info(and he sounded educated himself). In your case, you have a specific risk factor. How high it is would require a geneticist to tell you. But without even talking to one i can say personally, yes, were I in your position I would absolutely avoid HGH.
But that said, his is a very unique instance and has limited relevance outside the OP himself. There is absolutely no reason your average lifter should even think twice on this one. HGH is not going to give you cancer. Most in te oncology field would say this is the fairest statement. At worst, and again this is pure supposition in the cases I have read, HGH could promote or exacerbate cancer in persons who would have developed it sans HGH as well. Even here, there is precious little good mechanistic explanatory science to dig your teeth into. HGH promotes IGF-1. x% of tumored rats given igf1 showed accelerated tumor growth. Shocker... They are growth factors.
I am not going to be a blowhard about my background, but this is close to my wheelhouse. I think of this board as my bros, I care that you and your families are healthy and happy... And I am willing to say HGH is safe. Use it. I could be wrong but even if these studies are right and im wrong, worst case what does it show? Basically, that if HGH causes cancer it does so rarely. The numbers seen in these studies statistically significant but very low. Tons of things we use everyday have similar, to far far worse, risk profiles.
The fact that HGH makes your joints heal and last long, limits your bf and encourages exercise and good eating makes it way more likely to prevent cancer then cause it. Seriously.
Man, I knew this would turn into a book, I hope some find it coherent and valuable lol...
But for the worriers... From my understanding of things, HGH has become worrisome in promoting a few very specific cancers as data starts to trickle in. Note trickle, these studies are so small, most are not actual studies but reverse engineering of data, looking at what happened in certain treatment groups.
Overall, there has been endless conflicting data put out regarding any link between HGH and cancer. The two cancers of concern in adults with relation to HGH are Hodgkins Lymphoma and colon cancer. With Hodgkins while we understand the general mechanism, 3 causes one of which is a virus, but really have no idea about the nuts and bolts. So it's hard to make much of that one. The colon cancer, again unsubstantiated, makes logical sense. The colon is a constantly evolving, replenishing, replicating organ. Lots of division and differentiation of cells. Ideal place for cancer which is just a bad division or two away. J/k kind of. But it would make sense if a person were prone to this tragic division, HGH promoting cell growth and diff would allow more bites at the proverbial apple. But that's just supposition and again, it requires you predispose to cancer.
To close for anyone still reading, no study has shown anything truly alarming, just raised cause for investigation. The majority of said studies are far too small, not ideally performed, and deal with a vastly different demographic, non-GH producing children and juveniles.
But may I be the first to say, anyone who remains unconvinced by my post or overall, I respect your opinion and humbly request a PM so I can take the carcinogens of your hands ASAP.
but yeah BTC, my bad my friend.
