stackingplates.com
with some science
@302jrob
Interesting part to me, as far as fat loss, is the synergistic effects when incorporating DHT's. The last part however I personally wouldn't endorse because I don't like clen.
"COMPOUND SYNERGIES
When designing a fat loss stack that maximizes lipolytic potential, it would serve us well to choose compounds with a potential synergy, or additive effects upon one another. Earlier, we discussed some of the high-level mechanisms by which GH mediates its lipolytic effects. One of its key pathways involves the beta-adrenergic receptors. So it would seem plausible that if we can increase beta-pathway sensitivity and/or expression, they we can further optimize the overall lipolytic response to our stack.
Androgens induce potent lipolytic effects directly via androgen receptors expressed in adipose tissues [36]. This is cool, in and of itself, because it is a different pathway than GH uses however androgens have also been shown to increase beta-adrenergic receptor expression [37-38]. I’ve already discussed how increasing the number of coupled receptors in adipocytes could increase sensitivity and ultimately lipolytic potential, so this could be a potent synergy in our stack design methodologies.
The thyroidal axis and the GH/IGF axis have a very interesting, albeit complicated, relationship with one another. Of particular interest to lipolytic stack design is its impacts on beta-adrenergic receptor mRNA and more specifically its impacts on β3 expression, which has been shown to be a critical step in GH-mediated lipolysis [39-41]. In addition thyroid hormones stimulate synthesis, degradation, and mobilization of lipids resulting in increased levels of circulating FFAs [42]. And the last synergistic characteristic worth mentioning is that they, just like GH, appear to regulate the sensitivity of metabolic processes to catecholamines.
And once you have that increased beta-adrenergic receptor sensitivity and density, it only stands to reason that a beta-adrenergic agonist would be the icing on the cake to fully maximize fat mobilization potential. Clenbuterol [42] is an excellent candidate for stack addition here; however a comprehensive review of beta-adrenergic agonists is beyond the scope of this article."