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T3 and T4

TEST*

TEST*

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Any options on stacking both t3 and t4?
Doea adding t4 to the mix brings more fat loss?I found mixed opinions on the subject.Some advice 80% t3 and 20% t4 other say t3 is all i need.What do you guys think?

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Adding t4 while already using t3 will do nothing. Assuming you are not using a really really low dose of T3.

In order for your body to use t4 it has to be converted to T3 and if your levels of T3 are already high it wont convert it for use.
 
TEST* said:
Any options on stacking both t3 and t4?
Doea adding t4 to the mix brings more fat loss?I found mixed opinions on the subject.Some advice 80% t3 and 20% t4 other say t3 is all i need.What do you guys think?

Изпратено от моят SM-A520F с помощта на Tapatalk
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Yea use a t3/t4 combo on certain cycles. 50/500 ratio. It works well.

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Skinnyguy180 said:
Adding t4 while already using t3 will do nothing. Assuming you are not using a really really low dose of T3.

In order for your body to use t4 it has to be converted to T3 and if your levels of T3 are already high it wont convert it for use.
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Not true bro, the ratio is what keeps it from hitting the negative feed back loop

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Just to comment a little further, if you are running a hgh you want to do a combo of t3/t4 for the best synergy. Throw in a little tren and and a couple blast of clen and you'll be competition ready in no time

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Skinnyguy180 said:
What do you mean by negative feed back loop?
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The reason your body stops converting is because of the negative feed back loop. The body knows the t3 is already optimal but its becase the body looks at the ratio of the two. The balance, you can increase the t4 to the t3 and it will still have ability to convert, just not produce anymore t4. T3/T4 combo therapy is common in clinical settings for people who have tsh issues

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genixcon said:
I can provide links if you want. Just pm me

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Just post em here.. Its info for everyone.

From what I understand the T4 and t3 are produced in a ratio of about 80% T4 to 20%T3. In order to make T3, T4 for under goes de-iodination. And it is considered the active form of the two. I have only seen studies that show what high t3 can mean as far as whats wrong with your liver and the obvios side effects of elevated heart rate ect.. Never anything about a negative feed back loop.
 
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Skinnyguy180 said:
Just post em here.. Its info for everyone.

From what I understand the T4 and t3 are produced in a ratio of about 80% T4 to 20%T3. In order to make T3, T4 for under goes de-iodination. And it is considered the active form of the two. I have only seen studies that show what high t3 can mean as far as whats wrong with your liver and the obvios side effects of elevated heart rate ect.. Never anything about a negative feed back loop.
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I'll be happy to send it to you and you can post on here if you want. I'm not here to spoon feed the masses just dispels the myths

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genixcon said:
I'll be happy to send it to you and you can post on here if you want. I'm not here to spoon feed the masses just dispels the myths

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Spoon feeding the masses? This guys is asking a questions and it pertains to the answer

https://www.ncbi.nlm.nih.gov/books/NBK499850/

Is this the study you are referencing?

Because as I read it, the negative feed back loop has to do the the body producing TSH... Which will happen with doses of t3 and t4 that are greater than what is considered therapeutic and are closer to the doses used in body building.

Maybe Im wrong im not a doctor.
 
Skinnyguy180 said:
Spoon feeding the masses? This guys is asking a questions and it pertains to the answer

https://www.ncbi.nlm.nih.gov/books/NBK499850/

Is this the study you are referencing?

Because as I read it, the negative feed back loop has to do the the body producing TSH... Which will happen with doses of t3 and t4 that are greater than what is considered therapeutic and are closer to the doses used in body building.

Maybe Im wrong im not a doctor.
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No not that study. Although nih also thru the ncbi portal has a two studies I believe in reference to t3/t4 combo therapy. Just type in the search bar at the top

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genixcon said:
Heres one since I'm getting a guilt trip lol

https://www.ncbi.nlm.nih.gov/m/pubmed/30374427/

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genixcon said:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772692/

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Thanks for the read. These studies both specifically deal with adding T3 to patients already taking T4 and showed an increase in weight loss when compared to patients using T3 alone. Which seems logical given which of the 2 is considered the most active. And I did not see anything about a negative feed back loop when T3 is taken with with out T4 or showing that T3 taken with T4 prevents a ngeative feed back loop on the tsh

I guess the study that needs to be addressed would be taking T3 in combination with T4 Vs just T3 Vs higher dose T3

Based on reading I would assume that the additional weight loss achieved by adding T4 to T3 could also be achieved by just slightly increasing t3 given how much more active it is.

- - - Updated - - -

some one get chocomalt in here.. That dude can break this down for me.
 
Skinnyguy180 said:
Thanks for the read. These studies both specifically deal with adding T3 to patients already taking T4 and showed an increase in weight loss when compared to patients using T3 alone. Which seems logical given which of the 2 is considered the most active. And I did not see anything about a negative feed back loop when T3 is taken with with out T4 or showing that T3 taken with T4 prevents a ngeative feed back loop on the tsh

I guess the study that needs to be addressed would be taking T3 in combination with T4 Vs just T3 Vs higher dose T3

Based on reading I would assume that the additional weight loss achieved by adding T4 to T3 could also be achieved by just slightly increasing t3 given how much more active it is.

- - - Updated - - -

some one get chocomalt in here.. That dude can break this down for me.
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Ill dig in find a couple of more. There was one by Harvard med group and they had the best info I've seen yet on the relationship of the two.

How did you like the tnation article speaking about using t4 over t3 when running gh?

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genixcon said:
Ill dig in find a couple of more. There was one by Harvard med group and they had the best info I've seen yet on the relationship of the two.

How did you like the tnation article speaking about using t4 over t3 when running gh?

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That one I’m still reading. It’s a cool article for sure. I haven’t read anything about t2 before today. Thanks for posting up your references.

I’ve got a busy rest of the day so I probably won’t be posting until later tonight or tomorrow. But I’ll definitely follow up.


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TEST* said:
Any options on stacking both t3 and t4?
Doea adding t4 to the mix brings more fat loss?I found mixed opinions on the subject.Some advice 80% t3 and 20% t4 other say t3 is all i need.What do you guys think?

Изпратено от моят SM-A520F с помощта на Tapatalk
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You should click this link I'm going to put up and this really gives a good understanding of your T3 T4 and your thyroid . this really makes it easy for anyone to understand.
https://www.restartmed.com/thyroid-deiodinase/
 
Skinnyguy180 said:
Adding t4 while already using t3 will do nothing. Assuming you are not using a really really low dose of T3.

In order for your body to use t4 it has to be converted to T3 and if your levels of T3 are already high it wont convert it for use.
Click to expand...

this
 
Thanks brothers. quality info was given

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genixcon said:
Yea that's another good article. I think someone posted it on the evo board a while ago.

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Yes sir it was I! Lol.
It really helps understand the whole process. And rt3 as well.something not often talked about or discussed
 
macedog24 said:
Yes sir it was I! Lol.
It really helps understand the whole process. And rt3 as well.something not often talked about or discussed
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I'm on a lot boards lol. Good articles stick out tho. So much bro science, it's good when you see real science.

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genixcon said:
I'm on a lot boards lol. Good articles stick out tho. So much bro science, it's good when you see real science.

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Once in a while i say or post something that makes sense..
 
These compounds are definitely in the more advanced area of bodybuilding. Used when a person is on gh, slin, competitive types. Getting bloodwork is important as a lot of people have offset thyroid anyway. T4 is definitely used a lot more during gh runs. T3 is very potent and is used to drop a lot of weight, although it may not work and can backfire. Something that is not used too much except for competing.

Max
 

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