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New to TRT experiencing ED issues plz help

Dinger

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SB Labs
Week 6 of TRT @ 150mg cypionate injected twice weekly. This has been my protocol since starting treatment, has yet to be adjusted. Bloodwork shows my T:E ratio at 177:1

Recently experiencing ED issues and kind of dragging my ass again feely moody & unmotivated. 2 weeks ago i had the hardest most frequent erections of my life, and felt amazing in the gym.

I feel like my balls have shrunk and its nearly impossible to get an erection.

Im very active and my diet could not be any more dialled.

Week 6 bloodwork to follow. Please help.View attachment 197682
 
Following, hope you get some answers. I've been experiencing the same.
 
Testosterone looks good for TRT.

Estrogen is high normal, but nothing insane.

Hormones shouldn't be the issue. Might be mental right now.

You can try lowering estrogen and see how you respond.
 

Possible reasons you may experience ED on TRT​

Even though testosterone is often essential for proper erectile function, there are various reasons why ED can persist despite TRT. Here are some of the most common explanations.

Initial hormonal fluctuations​

When you first begin TRT, your body goes through a period of adjustment. During this time, your hormone levels fluctuate as they settle into the new balance. These fluctuations can disrupt your sexual function temporarily, leading to symptoms of ED. Your body needs time to adapt to the increased testosterone levels, and any changes in hormones during this phase could affect your ability to achieve or maintain an erection.

Impact on estrogen levels​

Testosterone can be converted into estrogen in your body through aromatization. While a certain amount of estrogen is important for male health, too much estrogen can have negative effects. Elevated estrogen levels can cause water retention, gynecomastia (enlarged breast tissue), and, in some cases, worsen ED. Some men experience an increase in estrogen levels when starting TRT, which can contribute to sexual dysfunction.

Suppression of natural testosterone production​

Testosterone replacement therapy can suppress your body’s natural production of testosterone. This can lead to a temporary drop in overall testosterone levels, especially if the TRT dose is not optimized. When your body is adjusting, there might be a period when your testosterone levels are lower than expected, leading to symptoms of ED. If this is the case, your healthcare provider may need to adjust your TRT regimen to achieve the right balance.

Underlying health conditions​

Many men seeking TRT also have other health conditions that contribute to ED, such as diabetes, cardiovascular disease, or obesity. These conditions can independently affect erectile function, and TRT may not fully address them. Even with optimized testosterone levels, if these underlying health conditions are not managed, ED can persist or worsen. For example, poor blood circulation or nerve damage from diabetes may continue to impact erectile performance despite testosterone supplementation.

Psychological factors​

Erectile dysfunction is not just a physical issue—it can also have psychological components. Anxiety, stress, depression, and relationship problems can all contribute to ED, regardless of testosterone levels. If you're struggling with these emotional or mental health issues, they can interfere with your ability to achieve or maintain an erection. TRT alone may not resolve the psychological aspects of ED, and addressing them through therapy or counseling can be crucial for improving overall sexual health.


Tips to manage ED while on TRT​

If you’re still experiencing ED while on TRT, there are several ways to address the issue. By taking a proactive approach and working with your healthcare provider, you can manage the situation and improve your sexual health.

Regular monitoring of hormone levels​

One of the most important steps you can take is to monitor your hormone levels regularly. This includes testosterone and estrogen levels, as well as other markers that may impact sexual function. Monitoring helps ensure that your hormone levels are within the optimal range and allows your healthcare provider to adjust your TRT regimen if needed. Blood tests should be a routine part of your treatment to ensure the best outcomes.

Consider PDE5 inhibitors​

In some cases, medications like sildenafil (Viagra) or tadalafil (Cialis) can be helpful in managing ED, even while on TRT. These drugs work by enhancing blood flow to the penis, making it easier to achieve and maintain an erection. PDE5 inhibitors can be used alongside TRT to address blood flow issues that may be contributing to ED. Discuss with your healthcare provider whether these medications are appropriate for you.

Address underlying health conditions​

If you have underlying health conditions like obesity, high blood pressure, or diabetes, managing these issues is essential to improving erectile function. TRT alone may not be enough if these conditions aren’t addressed. Lifestyle changes such as regular exercise, a balanced diet, and weight management can help improve overall health and sexual health. Effective management of these conditions may reduce or eliminate ED symptoms over time.

 
I think just about everyone that used TRT or higher has these issues at points in their journey. It's just part of the game. Normal functioning eugonadal me testosterone levels fluctuate daily. There is a cycle which is in sync with all the other components of the endocrine, paracrine, neurocrine etc pathways. You have added a blunt injection that does not conform to the normal diurnal cycle of the testosterone cycle. Is is such a chock that things go a little sideways? Sometimes things work fine and sometimes they are a mess. For instance, I am 63, been on TRT or cycles for decades. 3 months ago I needed viagra to get the deed done. This month I have morning wood and horny to the point where I shagged the Mrs 3 days in a row. The best advice I can give is roll with it. Keep some PDE5s on hand and just deal with it.
 
Even though Estro show high normal it’s probably way over normal of what it used to be. You can ride it out until it stabilizes or try to lower it with an AI, I would lower Estrogen since I feel better with low/mid estrogen. Either way, talk to your Dr.
 
I’m not going to act like I know a lot about this, but I’ve been in trt for almost 6 months now. First 50mg twice a week. Then the doctor raised it to 120mg twice a week. I haven’t changed the dose since then, but I have been injecting everyday versus twice a week. Also I have been doing hcg every other day. The hcg has been a game changer for me. I had started to have shrinkage and no sex drive or libido. I figured it might be estrogen related, once I got on the hcg it woke my nuts back up and I have been stellar since. Morning wood, good sex with the wife, and everything functioning how it did prior to the trt.


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I’m not going to act like I know a lot about this, but I’ve been in trt for almost 6 months now. First 50mg twice a week. Then the doctor raised it to 120mg twice a week. I haven’t changed the dose since then, but I have been injecting everyday versus twice a week. Also I have been doing hcg every other day. The hcg has been a game changer for me. I had started to have shrinkage and no sex drive or libido. I figured it might be estrogen related, once I got on the hcg it woke my nuts back up and I have been stellar since. Morning wood, good sex with the wife, and everything functioning how it did prior to the trt.


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I just purchased hcg5000 iu. I have been searching on reconstituting and dosages was curious to what your doing.
 
SB Labs
I just purchased hcg5000 iu. I have been searching on reconstituting and dosages was curious to what your doing.

I do about 250iu EOD.

I have dropped it recently though. I’ll start back up after I finish this cutting phase.



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