When do serum testosterone levels peak for enanthate during a cycle?

MyronGanes

Registered
Joined
Nov 15, 2014
Messages
101
Reaction score
4
Get Shredded!
When do serum testosterone levels peak for enanthate? 4 weeks? Or more?

The ester should affect when it peaks and the dose should affect what serum levels are when it does peak. at 300mg twice a week when will peak serum levels be attained during the cycle?


Thanks
 

Zyglamail

Registered
Joined
Jul 2, 2014
Messages
750
Reaction score
65
Technically, if dosing 2x a week with enth and taking the half life into account the blood levels will be highest just after your last injection of cycle. Based on enths half life you will still have some in your system when you take your next injection so your levels will slowly build over the course of the cycle. There is more than enough gear in your system after a single injection however to raise lab results.

All of that being said most people really start to notice the effects within 3-5 weeks, some as early as 2 weeks. The rate at which you start to notice things is largely dependent on your bodies state and readiness to take advantage of the hormone. Hormones are simply chemical messengers that trigger things to happen within the body. By taking more of a hormone that triggers desirable things to happen, like protein synthesis, muscle growth etc, it tells the body to ramp up certain bodily frunctions. These bodily functions do not happen in a vacuum, they require the raw materials for the complex chain of events to take place. Lack of building blocks = lack of results.
 

MyronGanes

Registered
Joined
Nov 15, 2014
Messages
101
Reaction score
4
Yeah Im interested in the mean serum level of testosterone during a cycle. I should have rephrased that. In order to know whether or not my stuff is underdosed I know I should have approximately 2400 ng/dl total testosterone towards the end of my cycle when it has "peaked". Essentially, id like to know when this peak does occur so if the gear is underdosed I would know sooner rather than later.

Now I do have a science background but I am lost as the way you guys throw the term half life around and the term "active half life". Any amount of the hormone after any amount of half lives is always active. Perhaps you guys mean effective half life?

Also, since enanthate is released from a depot I assume the half life does not take effect until the release so we must know a release rate AND the half life to scientifically determine the increase in serum testosterone levels.

OR. It can just be measured directly as a functin of time, which is the informatin Im looking for.

Free and total testosterone levels over 3 months at 300mg 2x week enanthate injections as a function of time. Any data out there?
 

Zyglamail

Registered
Joined
Jul 2, 2014
Messages
750
Reaction score
65
Unfortunately there is not a clear cut conversion of test dose to serum lab tests. The speed at which test disperses from the depot is also not a constant, it varies from individual to individual and is also influenced by injection location. About all you will find is anecdotal reports strewn about on what others have seen on labs ate various doses.

Without getting the actual AAS tested its nearly impossible to judge the strength of the AAS from lab work.

If you want to let lab work be your guide as to the potency, your best bet would be to run something like 100mg 2x a week or 200mg 1x a week for a few weeks and get labs then. Since many of us older guys on TRT get frequent labs, using a trt dose yourself would probably give you the largest base of labs to compare to.
 

jozifp103

Board Rep
Joined
Mar 29, 2014
Messages
3,457
Reaction score
1,288
Yeah Im interested in the mean serum level of testosterone during a cycle. I should have rephrased that. In order to know whether or not my stuff is underdosed I know I should have approximately 2400 ng/dl total testosterone towards the end of my cycle when it has "peaked". Essentially, id like to know when this peak does occur so if the gear is underdosed I would know sooner rather than later.

Now I do have a science background but I am lost as the way you guys throw the term half life around and the term "active half life". Any amount of the hormone after any amount of half lives is always active. Perhaps you guys mean effective half life?

Also, since enanthate is released from a depot I assume the half life does not take effect until the release so we must know a release rate AND the half life to scientifically determine the increase in serum testosterone levels.

OR. It can just be measured directly as a functin of time, which is the informatin Im looking for.

Free and total testosterone levels over 3 months at 300mg 2x week enanthate injections as a function of time. Any data out there?
Everyone's numbers will vary slightly. I will say however, that you total T should be much higher than 2700ng/dL if you're running 600mg a week. Your levels will peak around the 4 week mark and hold steady from there on out. 500mg a week (250mg 2X/wk) puts me around 3400ng/dL. Yours may vary, but that's just a reference.
 

Zyglamail

Registered
Joined
Jul 2, 2014
Messages
750
Reaction score
65
Also, just an FYI in case your not aware, some labs only state specific numbers up to a certain point. For example some labs will only give a number if its below 1500, anything over is just labelled "high".
 

jozifp103

Board Rep
Joined
Mar 29, 2014
Messages
3,457
Reaction score
1,288
Also, just an FYI in case your not aware, some labs only state specific numbers up to a certain point. For example some labs will only give a number if its below 1500, anything over is just labelled "high".
Valid point. It gets frustrating seeing threads with blood work claiming the product is legit when all the test says is >1500ng/dL. It could be 1501 for all we know lol.
 

John Johnson

Registered
Joined
Mar 12, 2014
Messages
741
Reaction score
65
Valid point. It gets frustrating seeing threads with blood work claiming the product is legit when all the test says is >1500ng/dL. It could be 1501 for all we know lol.

Would you know which test would show the actual amount of test in the blood instead of topping out at 1500. I order a testosterone only blood serum test but ended up with a >1500 reading.
 

jozifp103

Board Rep
Joined
Mar 29, 2014
Messages
3,457
Reaction score
1,288
If you're in the US there's
PrivateMDLabs.com. You can order the female hormone panel for $50 with a coupon code and it will give you everything you need for a hormonal and metabolic checkup, but will NOT read over 1500 for total T.
LabsMD.com. ​Female hormone panel. Same as above, but $73 and will read total T levels over 1500.
 

MyronGanes

Registered
Joined
Nov 15, 2014
Messages
101
Reaction score
4
Everyone's numbers will vary slightly. I will say however, that you total T should be much higher than 2700ng/dL if you're running 600mg a week. Your levels will peak around the 4 week mark and hold steady from there on out. 500mg a week (250mg 2X/wk) puts me around 3400ng/dL. Yours may vary, but that's just a reference.

The study that was posted on this site and was stickied in the newbie section said 61 men at 600mg per week had total testosterone values at a mean of 2400 ng/dl at 16 weeks if I remember correctly. Unfortunately they didn't test serum levels up to week 16. Lame data collection if you ask me. How is it that it varies so much from your values? That is a huge deviation.

Anyway, is there no study that takes a good sample of men, gives them any dose of enanthate and measures their testosterone levels weekly for a few months? It would be great to have some real data. I don't like leaving things to question especially with cycling and I wasn't able to get human grade under my circumstances.
 
Last edited:

chocolatemalt

Registered
Joined
Sep 1, 2012
Messages
6,137
Reaction score
949
Location
Purple Mountains
Everyone's numbers will vary slightly. I will say however, that you total T should be much higher than 2700ng/dL if you're running 600mg a week. Your levels will peak around the 4 week mark and hold steady from there on out. 500mg a week (250mg 2X/wk) puts me around 3400ng/dL. Yours may vary, but that's just a reference.

Here's a confirmation of that 4-week mark for equilibrium, in some graphs about midway down the page:

http://www.consultdrminas.com/aesthetic/hrt.html

I can't tell what the source of the data is however. The 7-day half-life used for test-e and c aren't quite accurate in my experience either -- it should be 5.5 days, but not a huge difference in the outcome.

Would you know which test would show the actual amount of test in the blood instead of topping out at 1500. I order a testosterone only blood serum test but ended up with a >1500 reading.

Joz gave you the good, short info but here's more if you want it. Sticky #1 in the Lab Testing forum: http://www.anabolicsteroidforums.com/forumdisplay.php/38-Lab-Testing

Yeah Im interested in the mean serum level of testosterone during a cycle. I should have rephrased that. In order to know whether or not my stuff is underdosed I know I should have approximately 2400 ng/dl total testosterone towards the end of my cycle when it has "peaked". Essentially, id like to know when this peak does occur so if the gear is underdosed I would know sooner rather than later.

Now I do have a science background but I am lost as the way you guys throw the term half life around and the term "active half life". Any amount of the hormone after any amount of half lives is always active. Perhaps you guys mean effective half life?

Also, since enanthate is released from a depot I assume the half life does not take effect until the release so we must know a release rate AND the half life to scientifically determine the increase in serum testosterone levels.

OR. It can just be measured directly as a functin of time, which is the informatin Im looking for.

Free and total testosterone levels over 3 months at 300mg 2x week enanthate injections as a function of time. Any data out there?

Judging from the blood level charts above, you'll reach a peak test level on any day immediately after a pin after 4 weeks into the cycle. It takes about a day for the pin to take full effect, the "depot delay". This will put you at the peak of a tooth on the sawtooth curve. Bear in mind that the protocol results in the Lab Testing forum don't work this way -- blood draw is always 7 days after the last pin, so you'll expect a reading then that is about half of the peak.

"Active half life" appears to be a fat-fingered non-scientific concept put into a list that has had a lot of travel in the steroid forums, and unfortunately it's polluted the discussion. The list is apparently the "active lives", not half lives, meaning the time it takes for the drug to decay to 25% of peak blood level (an arbitrary mark) at which point we decide it's no longer effective. This is two half lives so the numbers should be double the actual serum half lives. E.g. test-e H/L is 5.5 days so the active life is 11 days. This sorta matches the 10-14 days bandied around in that "active half life" list.

Unfortunately that particular list appears to have some fabricated numbers where the theory of ester length equalling a tightly predictable half-life was adhered to, so test-e shows one half-life and test-c shows another about 20% longer. The data don't support this. Both esters have the same half life in actual studies. The ester length does matter but not in a linearly predictable manner. So, we have to be suspicious of all the other "data" in that list.

And yeah there's a depot contribution to the half-life but I haven't found a lot of info on it. I suspect it's 1.5 days or so on average, pushing the 5.5 h/l of test-e to 7 days if measuring from the last pin.

In "free fall" mode, what I call the non-pinning decay of test-e with no depot effect, I've had several lab tests showing a 5.5 day h/l very consistently. This may vary a little from dude to dude but studies I've seen don't seem to show a lot of variation here. As for the depot, that would seem to vary more: Did it go into muscle and not fat? (A common issue with dorsal glute pins.) Is the dude a high- or low-metabolism sort? Is he reacting to the oils or not? I'm just speculating but it would be interesting to know how these things throw the curves.
 

chocolatemalt

Registered
Joined
Sep 1, 2012
Messages
6,137
Reaction score
949
Location
Purple Mountains
The study that was posted on this site and was stickied in the newbie section said 61 men at 600mg per week had total testosterone values at a mean of 2400 ng/dl at 16 weeks if I remember correctly. Unfortunately they didn't test serum levels up to week 16. Lame data collection if you ask me. How is it that it varies so much from your values? That is a huge deviation.

Anyway, is there no study that takes a good sample of men, gives them any dose of enanthate and measures their testosterone levels weekly for a few months? It would be great to have some real data. I don't like leaving things to question especially with cycling and I wasn't able to get human grade under my circumstances.

Here is that study:

http://ajpendo.physiology.org/content/281/6/E1172.full

The bloods were taken a week after the final pin. So the 2400 ng/dL they got would've been doubled to more like 4800 a day after that pin. To me this means an "8x" multiplier on the mg dosage -> ng/dL results, which is pretty good. Pharm grade, I assume. I've gotten as low as 4x on some gear, which was better than bunk but still...

I feel your pain on the lack of data. :) I'd like to see a hell of a lot more charts too but there just isn't much since using testosterone as a PED is illegal, and TRT is still somewhat of a new industry and usually keeps doses low in any case. The best chance we have to get solid data is to do our own blood work and post results in this forum.

In fact you could get started on that by having weekly blood work on your own cycle. Go now, do it! :D
 

MyronGanes

Registered
Joined
Nov 15, 2014
Messages
101
Reaction score
4
Here is that study:

http://ajpendo.physiology.org/content/281/6/E1172.full

The bloods were taken a week after the final pin. So the 2400 ng/dL they got would've been doubled to more like 4800 a day after that pin. To me this means an "8x" multiplier on the mg dosage -> ng/dL results, which is pretty good. Pharm grade, I assume. I've gotten as low as 4x on some gear, which was better than bunk but still...

I feel your pain on the lack of data. :) I'd like to see a hell of a lot more charts too but there just isn't much since using testosterone as a PED is illegal, and TRT is still somewhat of a new industry and usually keeps doses low in any case. The best chance we have to get solid data is to do our own blood work and post results in this forum.

In fact you could get started on that by having weekly blood work on your own cycle. Go now, do it! :D

Great reponse. Trust me if I actually lived in the states where getting blood tests wasnt a hassle I would definitely do it. I will get less frequent bloods now but Ill be using UG stuff so it skews the data since the dose is unknown anyway. The least I can do is to ensire that my T levels are where they are supposed to be on cycle and just compensate for underdosed gear with more volume administered.
 

s2h

Registered
Joined
Aug 8, 2012
Messages
6,018
Reaction score
456
Nobody is going to get the same results lab wise...nobody...

Pin 2 x ew for 3 weeks....after the last pin of week 3 wait 7 days and draw labs...is it a perfect method?..No...but it will give you a fairly good idea were your at...then after the labs go home and keep pinning....

Results you can stick on a bell curve of other similar labs....give it 10% either way....outside of that there could be a issue...
 
Top