It's the nuclear weapon of acne meds so it's gonna work unless you're amazingly unlucky. The bigger danger is sides so watch for em and prepare to lower the dose as needed. Cracked and bleeding lips, inflamed eyes, dried sinuses and nosebleeds, non-healing eczema, colonic prolapse. Ok that last one doesn't happen... that I know of.
If after a month or so you find you can lower it to 5mg/day and still stay clear that's the way to go. Even lower if it works... least effective dose is the goal.
What's your source?
For people with deep cystic acne or moderate-to-severe cases, hygiene is mostly a big waste of time. Whether a pore clogs and infects into a zit depends on the bacteria, your immune system, and consistency of sebum... whether and with what you wash it all is unlikely to matter. When I'm off accutane I could scrub my face 10x/day with hot rags and powerful soap, trying all sorts of expensive brands of soaps, exfoliants, lotions, and still be a pizza face. I did that shit for years, even mixing in full strength Retin-A gel, topical erythromicin, lots of other stuff only mildly effective. But if I'm on accutane I could skip DAYS at a time of hygiene altogether and still stay 100% clear. Cleanliness for me is completely irrelevant, and studies show that's also the case for most people unless their condition is truly mild -- some whiteheads and blackheads, superficial stuff. Most derms know this and will admit most of the OTC products are placebos. But they're stingy with the accutane too.
Bah, didn't mean to lecture but I'm seeing a lot of hygiene-related "solutions" above that for many people will be frustratingly bunk. I learned the hard way.
