SemaGlutide Cheat Sheet

[GYMnTONIC]

Semaglutide​

Generic name: semaglutide
Brand names: Ozempic, Wegovy, Rybelsus
Dosage form: subcutaneous injection, tablet
Drug class: Incretin mimetics

Medically reviewed by Melisa Puckey, BPharm. Last updated on Jun 8, 2022.

• Uses
• Warnings
• Before taking
• Dosage
• Side effects
• Interactions
• FAQ

What is semaglutide?​

Semaglutide (Wegovy, Ozempic, Rybelsus) is a medicine used for weight loss in specific patients, and to lower blood sugar levels and reduce the risk of major cardiovascular events such as heart attack or stroke in type two diabetes patients. Semaglutide is a GLP-1 agonist and works by increasing insulin release, lowering the amount of glucagon released, delaying gastric emptying and reducing appetite.


Semaglutide is not for use in people with type 1 diabetes.

Each of the different brands of semaglutide (Wegovy, Ozempic, Rybelus) are FDA approved for different conditions.

What is the difference between Wegovy, Ozempic and Rybelus?​

The different brands of semaglutide have different uses and different forms:

• Wegovy (subcutaneous injection) is used for weight management for a specific group of patients and is given as a subcutaneous injection weekly.
• Ozempic (subcutaneous injection) is used lower blood sugar levels for type two diabetic patients, along with diet and exercise. It is also used for diabetic patients who already have cardiovascular disease, to help lower the risk of major cardiovascular events such as heart attack or stroke. Ozempic is given as a subcutaneous injection weekly.
• Rybelsus (tablet) is used to lower blood sugar levels for type two diabetic patients along with diet and exercise, and is taken as a tablet once a day.

Brand of semaglutide	Ozempic	Wegovy	Rybelsus
Form	subcutaneous injection	subcutaneous injection	tablet
Strength	0.25 mg or 0.5 mg dose pen, 1 mg dose pen, 2mg dose pen.	0.25 mg dose pen, 0.5 mg dose pen, 1 mg dose pen, 1.7 mg dose pen, 2.4 mg dose pen	3mg tablet, 7mg tablet, 14mg tablet
Dose	weekly	weekly	daily
Uses	Used to help control blood sugar levels in type 2 diabetic patients, it is used together with diet and exercise. It is also used to reduce the risk of major cardiac events such as heart attack and strokes in type 2 diabetic patients who already have cardiovascular disease.	Used for weight loss for patients who have an initial BMI (body mass index) of 30kg/m2 or greater or patients who have a BMI of 27kg/m2 or greater and also have least one weight-related condition, such as high blood pressure, type 2 diabetes and high cholesterol. It is use together with diet and exercise.	Used to help control blood sugar levels in type 2 diabetic patients, it is used together with diet and exercise.

Warnings​

Call your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.

You should not use semaglutide if you have multiple endocrine neoplasia type 2 (tumors in your glands), or a personal or family history of medullary thyroid cancer.

 

[Phill]

this kills your appetite in no time

 

[Powerhousehb]

I tried this. Got a prescription from my doctor. It only worked on week one. Literally killed my appetite. A little nausea. Week 2, 3, 4 didn't do anything for me. Squat! I am using pre loaded Weogy pens from my pharnacy. My doctor told me I'm one of the few people that my body must have gotten used to it. I did not try rasing the dose since I would have to go to my doctor and get another prescription. I didn't care for how it slowed down my intestines. I went from having dailey bowl movements to every second or third day and felt real bloated at the begining. I imagine if you not eating much it's only a problem in the begining.

There's no short cuts to shedding body fat. My doctor was cool and let me try it. But if I can't eat I shrink. Can't have that. So I will do it the right way. Diet and cardio.