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Who's excited for Retatrutide?
What makes Retatrutide unique is that it targets THREE receptors.
Semaglutide targeted the receptor glucagon-like peptide-1 (GLP-1), and Tirzepatide targeted both the GLP-1 receptor and glucose-dependent insulinotropic peptide (GIP) receptor.
This potentially all-powerful weight loss drug tackles GLP-1 and GIP receptors while also targeting the body’s glucagon receptors.
Supposedly, what this does is give the drug a DIRECT effect on energy expenditure (unlike its predecessors).
We effectively have a lowering of appetite from GLP-1, improved fat clearance and stimulate the release of lipoprotein lipase from fat with GIP, and a higher metabolic rate with the glucagon receptor.
Take a look at this early preclinical study done in mice and tell me your mind isn’t BLOWN AWAY:
Tirzepatide is in blue and Retatrutide is in red — not only is the total weight loss significantly larger, but the majority of weight loss is pure fat.
What makes Retatrutide unique is that it targets THREE receptors.
Semaglutide targeted the receptor glucagon-like peptide-1 (GLP-1), and Tirzepatide targeted both the GLP-1 receptor and glucose-dependent insulinotropic peptide (GIP) receptor.
This potentially all-powerful weight loss drug tackles GLP-1 and GIP receptors while also targeting the body’s glucagon receptors.
Supposedly, what this does is give the drug a DIRECT effect on energy expenditure (unlike its predecessors).
We effectively have a lowering of appetite from GLP-1, improved fat clearance and stimulate the release of lipoprotein lipase from fat with GIP, and a higher metabolic rate with the glucagon receptor.
Take a look at this early preclinical study done in mice and tell me your mind isn’t BLOWN AWAY:
Tirzepatide is in blue and Retatrutide is in red — not only is the total weight loss significantly larger, but the majority of weight loss is pure fat.
