Injectable B12 Experience?

[jozifp103]

I have access to some pharma B12 amps and wondering if I should take the dive. Basically I'm looking for 2 things.....energy and appetite stimulation. I hear B12 is great for increasing appetite and of course provides great natural energy.


Now it's well known that the body excretes any excess B vitamins that it doesn't use and I've seen people take some pretty hefty doses of B12. Now, is it redundant to take such high doses? Will the body use anywhere near that amount? And most importantly.....does the shit actually work? Do you feel more energy? Appetite?


Thanks in advance homies.

 

[Iron_Mike]

stings a bit

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[Iron_Mike]

I didn't notice much, but I think alot of the stuff we eat had b12 in it, so if your not deficient you probably won't notice anyrhing

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[bigmills]

Are you stynthelym, it has a ester in it so i do not have to inject every day but I don't notice a difference in appetite that's for sure..

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[JRotten]

There are three forms and they have different half lives. I have seen many different protocols but the b12 manufacturer I was looking at yesterday was recommending 3x dosing at 2500mcg which is way off of what I've generally seen which is 500 day 1-3 and 250 ed after that

 

[dave_236]

There's really no benefit in injectable over oral b12 except in people with pernicious anemia who have a lack of intrinsic factor and aren't able to absorb b12 through the GI tract. Plus as you mentioned you'll just be making expensive urine if you take more than you need.

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[Tall Deck]

the injectable B-12 (from another sponsor though) didn't do anything for me

 

[chocolatemalt]

I think it'll do nothing (beyond placebo) for those of us without B12 issues. I've tried it too, no difference.

I have a close relative that had years of serious depression and chronic fatigue syndrome before discovering it was an age-related B12 absorption problem. She was eating plenty of meat but no help... stomach acid too weak? Can't remember the detailed root cause. But injectable B12 changed her life.

 

[JRotten]

I was surprised to find out I was deficient since it definitely wasn't a diet issue. Also like a lot of things your needsay change with things like a big blast. It's cheap enough and can be mixed with peptides so that it may be worth looking into just to see what it does.

 

[ILIFT2LIVE]

Its great stuff. Energy and immuje system boost. Metabolism boost


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[Tall Deck]

I think it'll do nothing (beyond placebo) for those of us without B12 issues. I've tried it too, no difference.

I have a close relative that had years of serious depression and chronic fatigue syndrome before discovering it was an age-related B12 absorption problem. She was eating plenty of meat but no help... stomach acid too weak? Can't remember the detailed root cause. But injectable B12 changed her life.

If I remember correctly, it's something in your stomach called the "intrinsic factor" which some people have a shortage of, which prevents vitamin B-12 from being digested/absorbed/synthesized.

 

[chocolatemalt]

If I remember correctly, it's something in your stomach called the "intrinsic factor" which some people have a shortage of, which prevents vitamin B-12 from being digested/absorbed/synthesized.

Nice catch! I had to research that one...

https://en.wikipedia.org/wiki/Intrinsic_factor

I need to ask my relative if that was her issue.

Actually on further reading I think it may have been the low stomach acid problem I mentioned before (caused by an autoimmune gastritis, afflicts 10-15% of the elderly) since that's the usual culprit when the deficiency is age-related.

https://www.ncbi.nlm.nih.gov/pubmed/10448529

It looks like the intrinsic factor issue is genetic and age-irrelevant, but I haven't invested hours of reading in it either so not certain.

 

[Tall Deck]

Nice catch! I had to research that one...

https://en.wikipedia.org/wiki/Intrinsic_factor


It looks like the intrinsic factor issue is genetic and age-irrelevant, but I haven't invested hours of reading in it either so not certain.

Yes, I believe that's true. Age has nothing to do with that particular condition. And I also believe that it can cause some people to become anemic due to lack of B-12 getting into their system. I remember dating this skinny chick who had a tough time reaching the 100lb mark due to her lack of appetite and being anemic. I used to do push-ups with her on my back despite the bench press being one of my weak points in the gym. I used to take her out to eat on a daily basis just in an effort to get her to eat. The doc gave her vitamin B-12 pills to take to increase her appetite, but they didn't seem to work that well for her. Anyway, the daily dinner dates got old pretty quick for me, since I was more concerned about her health than she seemed to be. So I realized that I was just wasting my money

 

[dave_236]

Yes the disease is called pernicious anemia. Intrinsic factor is an enzyme produced in the stomach that is required for the metabolism of orally ingested b12 either in food or supplements. It can be a very serious condition even leading to death. Injections of b12 allow the GI tract to be skipped so for those people it's a lifesaver but it is of no extra value for people who produce intrinsic factor.

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[chocolatemalt]

Yes the disease is called pernicious anemia. Intrinsic factor is an enzyme produced in the stomach that is required for the metabolism of orally ingested b12 either in food or supplements. It can be a very serious condition even leading to death. Injections of b12 allow the GI tract to be skipped so for those people it's a lifesaver but it is of no extra value for people who produce intrinsic factor.

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That's interesting, so the oral B12 would be inactive in the GI tract but should work just fine sublingually... if the person has the patience to let it sit there in powder form for 5+ mins. But I just read a study saying they could find no advantage to sublingual administration with anyone, suggesting something wrong with this picture. Dunno what though. And I fatigued on research atm lol.

 

[Montego]

That's interesting, so the oral B12 would be inactive in the GI tract but should work just fine sublingually... if the person has the patience to let it sit there in powder form for 5+ mins. But I just read a study saying they could find no advantage to sublingual administration with anyone, suggesting something wrong with this picture. Dunno what though. And I fatigued on research atm lol.

Sublingual b12 works but, you have to take around 5x the amount of an injection for the same effects.

 

[TrainInsane89]

I got a few amps a while back, ive only used one i still have a few left ive been meaning to use. Cant really say i noticed anything substansial. Next time ill pay much more attention to any effects it produces.