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Did you know that when you take your Orals, you are actually only getting a fraction of the actual compound. This in laymens terms is due to first pass metabolism, where alot of the drug is destroyed by the liver. Oral administration has an estimated absorption rate of 5-20% (varies per compound), whereas Transdermal applications have an estimated absorption rate of 30-60% (varies per compound)
Read more to find out the best way to optimize your orals...
Patches and cream avoid first-pass metabolism. Possibly the drug doesn't absorb in the GI tract well and effectively has a low bioavailability. In addition, the drug may be rapidly metabolized in the liver. While the bioavailability of a patch is also fairly low, depending on where the patch is placed, it could avoid those two routes of metabolism and elimination.
Traditional methods of administering medicine such as tablets or capsules get watered down and become much less effective due to stomach acids and digestive enzymes, before they eventually get into the bloodstream. Bypassing the stomach and liver means a much greater percentage of the active ingredient goes straight into the bloodstream where it's needed. In many cases, transdermal methods are used to help avoid potential side effects such as stomach upset or drowsiness. The full potential for transdermal medicine has not been explored by modern medicine though it has been practiced for thousands of years in hot springs around the world."
Transdermal delivery provides a low constant level of hormone in the blood, and avoids hepatic protein synthesis stimulation.
Orally available testosterone (such as methylated androgens) is relatively insoluble and associated with significant first-pass metabolism, which results in limited effectiveness and a poor safety profile
http://www.nature.com/ijir/journal/v19/n4/full/3901562a.html?foxtrotcallback=true
So the first thing you need to do is to purchase the SALVO. I have personally chosen Iron Legions version because I have used it dozens of times over the years and I find it to be safe and effective and easy to use, while still affordable.
LINK TO BUY SALVO
http://stores.gymntonic.com/iron-legion-salvo-make-transdermal-product-with-raw-powders/
Next if you have your orals in Pill or Tablet form you simply buy a Coffee Grinder (pictured below) I got mine at target for $20 bucks. Make sure you do the math before just grinding up some tablets. For example, lets say you wanted to use "pink stop signs". We know these are 10mgs per tablet generally. The salvo in general can suspend anything up to 100mgs per mL (though I have gotten it higher personally). A bottle of Salvo is 30mL. So if you wanted to make 100mgs per mL of this compound you would need 300 tabs of "pink stop signs". Or another example, lets say you wanted to make GREEN GIANTS suspended at 100mgs per mL. We know those are 50mgs per tablet. So you would need 60 Green Giant tablets to make your Salvo into a 100mg per mL suspension.
So anyways calculate your math and double and then triple check it to figure out the appropriate amount of product you need before you begin the process.
Now to actually create the Transdermal using the Iron Legion Salvo. It's simple and I have written an article to show you how to do it.
How to make Transdermals Article
http://stores.gymntonic.com/blog/how-to-make-raw-powders-into-transdermals/
**Caution**
Be aware that just like test creams, etc..if you have children or gf/wives..the area that you applied the Transdermal (TD) PH to..can certainly have some absorption in those children/wives, etc..so proceed with caution.
Sources:
http://www.nature.com/ijir/journal/v19/n4/full/3901562a.html?foxtrotcallback=true
www.lavitarx.com/getdoc/470f33ea-ef0f-4e0e-be42-0450baca0986/v7c6-a-comparison-between-oral-and-transdermal-hor.aspx
http://www.naturalnews.com/024142_skin_medicine_magnesium.html
https://www.ncbi.nlm.nih.gov/pubmed/10434286
Read more to find out the best way to optimize your orals...
Patches and cream avoid first-pass metabolism. Possibly the drug doesn't absorb in the GI tract well and effectively has a low bioavailability. In addition, the drug may be rapidly metabolized in the liver. While the bioavailability of a patch is also fairly low, depending on where the patch is placed, it could avoid those two routes of metabolism and elimination.
Traditional methods of administering medicine such as tablets or capsules get watered down and become much less effective due to stomach acids and digestive enzymes, before they eventually get into the bloodstream. Bypassing the stomach and liver means a much greater percentage of the active ingredient goes straight into the bloodstream where it's needed. In many cases, transdermal methods are used to help avoid potential side effects such as stomach upset or drowsiness. The full potential for transdermal medicine has not been explored by modern medicine though it has been practiced for thousands of years in hot springs around the world."
Transdermal delivery provides a low constant level of hormone in the blood, and avoids hepatic protein synthesis stimulation.
Orally available testosterone (such as methylated androgens) is relatively insoluble and associated with significant first-pass metabolism, which results in limited effectiveness and a poor safety profile
http://www.nature.com/ijir/journal/v19/n4/full/3901562a.html?foxtrotcallback=true
How do I turn my orals into Transdermals?
So the first thing you need to do is to purchase the SALVO. I have personally chosen Iron Legions version because I have used it dozens of times over the years and I find it to be safe and effective and easy to use, while still affordable.
LINK TO BUY SALVO
http://stores.gymntonic.com/iron-legion-salvo-make-transdermal-product-with-raw-powders/
Next if you have your orals in Pill or Tablet form you simply buy a Coffee Grinder (pictured below) I got mine at target for $20 bucks. Make sure you do the math before just grinding up some tablets. For example, lets say you wanted to use "pink stop signs". We know these are 10mgs per tablet generally. The salvo in general can suspend anything up to 100mgs per mL (though I have gotten it higher personally). A bottle of Salvo is 30mL. So if you wanted to make 100mgs per mL of this compound you would need 300 tabs of "pink stop signs". Or another example, lets say you wanted to make GREEN GIANTS suspended at 100mgs per mL. We know those are 50mgs per tablet. So you would need 60 Green Giant tablets to make your Salvo into a 100mg per mL suspension.
So anyways calculate your math and double and then triple check it to figure out the appropriate amount of product you need before you begin the process.
Now to actually create the Transdermal using the Iron Legion Salvo. It's simple and I have written an article to show you how to do it.
How to make Transdermals Article
http://stores.gymntonic.com/blog/how-to-make-raw-powders-into-transdermals/
**Caution**
Be aware that just like test creams, etc..if you have children or gf/wives..the area that you applied the Transdermal (TD) PH to..can certainly have some absorption in those children/wives, etc..so proceed with caution.
Sources:
http://www.nature.com/ijir/journal/v19/n4/full/3901562a.html?foxtrotcallback=true
www.lavitarx.com/getdoc/470f33ea-ef0f-4e0e-be42-0450baca0986/v7c6-a-comparison-between-oral-and-transdermal-hor.aspx
http://www.naturalnews.com/024142_skin_medicine_magnesium.html
https://www.ncbi.nlm.nih.gov/pubmed/10434286
