When I get ready to go down that road you will be the first person I contact. Right now I’m trying to stay as natural as I can. Cjc1295/Ipamorelin. I know to get to where I want to be I will probably have to up my game. Right now I’m making small progress but I wish I was a little further along. So far my abs are my weak spot and I’m crunching like crazy but still having trouble with that 1” of belly fat.lol.
Keep up the hard work and thank you for sharing. It keeps me motivated and a goal to try and achieve.
Cjc1295/Ipamorelin can be a helpful combo for sure and I’ve personally used both and plenty more . That lower abdomen fat is the last to go on males and can be a bitch. Of course keeping your optimum levels of free/total testosterone/gh/igf-1 is nice but hard to get balanced along with the diet and exercise .
Here are some extra articles that I’ve went through along with my own experiences :
PEPTIDE MIXED THERAPIES :
MK677 vs Ipamorelin: Summary
In the competition of MK677 vs Ipamorelin, there is no clear-cut winner. Rather, there are two different compounds with extreme similarities and yet some nuanced differences that make choosing one compound over the other obvious in certain situations. Though the combination of MK677 and Ipamorelin has not been tested, there is reason to think that the compounds may be synergistic in many ways. Only future research will tell what the combination of these growth hormone secretagogues might do. For the time being, MK677 vs Ipamorelin is less a matter of determining a “winner” than it is an exercise in learning about two exceptional compounds and their impacts on GH physiology.
If there is one place that MK677 outshines Ipamorelin it is in the realm of sleep.
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•Difference between Sermorelin and Modified GRF 1-29 ?
Sermorelin is often confused with Modified GRF 1-29. They are both similar but these two peptides do have an important difference. These two peptides have a molecular structure comprised of 29 amino acids and possess comparable mechanisms of action (mimicking GHRH to stimulate endogenous GH production).
On the other hand, Modified GRF 1-29 has been altered with changes to four specific amino acids in its chemical structure. These changes are intended to increase the peptide’s stability during storage, transportation, and administration while enhancing its affinity for the GHRH receptor.
What are the Benefits of Sermorelin?
- naturally improves growth hormone production
- increased muscle
- increased lean body mass
- decreased body fat
- enhanced recovery from injuries and training sessions
- better sleep; deeper, more restful sleep
- improved flexibility and joint health
- enhanced overall health and wellness
- increased levels of GH stimulate greater production of Insulin-like Growth Factor 1 (IGF-1) in the body, further driving improvements in lean body composition with accelerated growth of muscle tissue and reduced body fat
Lower than optimal levels of growth hormone in the body can significantly affect an individual’s athletic performance, functional capacity, and overall quality of life. Growth hormone is a crucial component in numerous physiological processes: increased strength, energy, flexibility, vitality, and overall well-being. Suboptimal levels of growth hormone levels is often associated with loss of muscle mass and strength, weaker bones, reduced exercise capacity, increased body fat, decreased stamina, poor recovery, and unrestorative sleep.
•Combinations of Peptides:
Many peptides work well alone, but when they are combined with another peptide they are considered to have a synergistic effect, meaning the effects of both peptides are henced but combining them then using them alone. To enhanced GH production, peptides such as GHRP-2, GHRP-6, or Ipamorelin in combination with Sermorelin can result in a powerful synergistic effect.
These peptides’ complementary mechanisms of action can stimulate even greater secretion of GH, resulting in augmented IGF-1 production, improved muscle tissue growth and repair, accelerated wound healing and recovery, enhanced fat metabolism (fat loss), and more powerful anti-aging effects.
Dosage:
Sermorelin dosages commonly range from 200mcg -500mcg given 1 to 3 times daily. The peptide is commonly administered once daily before bed or split into 2 – 3 smaller doses spread throughout the day. Both approaches to administration can be effective and have been shown to have a positive results in clinical studies.
Although Sermorelin has a relatively short half-life of 10 – 20 minutes, the peptide stimulate the release of GH for 2 hours after administration. As a result, protocols delivering 3 daily doses of as little as 100 mcg (0.1mg) per administration have been shown to cause a significant increase in GH and IGF-1 secretion. Protocol such as this one will commonly result in a more consistent GH level on a daily basis.
Once daily protocols with administration before bed are very effective and better for ease of use and patient compliance. Clinical studies have shown a once daily injection before bed to produce a substantial increase in 12 hour nocturnal GH production as well as an overall increase in GH and IGF-1 levels. A once-daily protocol, recommended individual dosages are commonly 10mcg (0.1mg) per kilogram (2.2 pounds) of body weight. For example, a 200 lbs man would need approximately 900 mcg (0.9mg) once daily. Most doses of 10 mcg/kg are very effective with a maximum of 20 mcg/kg per day. Higher doses have not shown to be effective.
**Benefits of Sermorelin & IPA(Ipamorelin)
While results of using Sermorelin & IPA may vary from one patient to another, studies have shown that the anti-aging treatment of this combination peptides leads to a vast range of mental and physical benefits which include:
- The increase of lean-body mass
- Body fat reduction
- Improved energy in the body
- Increased vitality
- Increased strength & endurance
- Improved vision & brain cell aging
- An accelerated rate of healing wounds
- Improved immune and cardiovascular functioning
- Better quality of deep sleep
- Improvement of bone density
- Higher collagen density and improved skin quality

Sermorelin & Ipamorelin: The Powerful Synergy Peptides
There is a new Sermorelin with IPA, that is well known for being the most powerful among the GHRP peptides. both stimulate the patient’s own pituitary gland by binding to specific receptors that increase production and secretion of endogenous Human Growth Hormone (HGH). IPA also acts as an appetite suppressant allowing for increased weight loss. IPA reduces fat in the belly via a process known as lipolysis.
Additional benefits of IPA include:
First Month
● Weight loss/Body fat reduction
● Increase deep, vivid dreams
● Better, sounder sleep
● Improved stamina
● Optimistic attitude
Second Month
● Improved muscle tone
● Increased strength
● Improved skin tone
● Improved nail growth
● Better digestion
● Weight loss/Body fat reduction
● Improved vision
● Enhanced sexual function
Third Month
● Improved mental process
● Enhanced productivity
● Faster wound healing
● Hair regrowth
● Increased libido
● Increased muscle size
● Faster recovery from muscle soreness
● Reduced PMS symptoms
● Greater body flexibility
● Reduced pain
Fourth Month
● Heightened improvements
● Improvements may seem to plateau
● Rejuvenation is a process
Fifth Month
● Improved weight loss and reduction of inches
● Improved skin texture and appearance
● Skin thickening and greater elasticity
● Reduction of skin wrinkles
● Thickening of hair with a shiny, healthy appearance
● Continuation of improved muscle
Sixth Month
● Diminished cellulite
● Improved resistance to colds, flu, and other diseases
● Improved eyesight
● Healing of old wounds
● Disappearance of pain and soreness
● Improved body contour
Benefits of CJC 1295 w/Ipamorelin
- Increases fat loss and improves lean muscle mass
- Builds collagen and reduces wrinkles
- Improved bone density
- Strengthens the cardiovascular system
- Improves sex drive
- Boosts energy levels
- Improves mood and sleep
- Speeds wound healing and physical recovery
- Anti-aging effects
What is CJC 1295 Ipamorelin?
CJC-1295 w/Ipamorelin is a combination of two peptides designed to stimulate the body’s release of growth hormone (GH). CJC-1295 is an analog of growth hormone releasing hormone (GHRH) which improves plasma concentrations of both growth hormone and insulin-like growth factor 1 (IGF-1). CJC-1295 was formulated to have a long biologic half-life thereby increasing its effectiveness when compared to other growth hormone peptides. Ipamorelin is a 5 amino acid peptide that functions as a growth hormone secretagogue (increases GH secretion) and increases IGF-1 levels as well. This peptide is often combined with CJC-1295 for its positive effects on muscle growth and maintenance.
Now I’ve had good luck with Sermorelin Forte Plus which is a sermorelin/ghrp6/ghrp2 combo 4 days and gh 3 days a week . But that was more for a bulking phase .
The sermorelin/Ipamorelin combo could help by using that early upon waking and mk677 at night before bed . I don’t have experience with tesamorelin, but I do know that gh and mk677 used in low doses have shown to be superior to all the peptides. Most use their 2iu AM gh dose, then mk677 before bed (12.5mg-25mg)
watching blood glucose and thyroid is key (even TRT can cause yout tsh to raise) so getting bloodwork is important . Sometimes just a little Rx of levothyroxine T4 can boost your levels and lower that tsh improving your metabolism and burning fat.
Hope that helps give you some extra information. All of the medications are prescribed in the US at clinics but can cost a lot .
Max