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Total Testosterone vs. Free Testosterone vs. Bio Avail Testosterone

GSRacer

GSRacer

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Get Shredded!
I recently posted some lab work that showed a high total testosterone level due to exogenous supplementation (4890ng/dL) . Included in the results was a reading on "bio avail" testosterone. This number was 4157 ng/dL, which seemed very high relative to total test. I mistakenly thought at first that bio avail test is equivalent to "free" test. Free test represents all the testosterone in your blood that is not bound to SHBG (http://en.wikipedia.org/wiki/Sex_hormone-binding_globulin), and is thus available for use. Bio avail test is actually a more accurate reading of how much testosterone is available for use by your tissues, because there is a significant amount of testosterone that is bound very lightly by Albumin (http://en.wikipedia.org/wiki/Albumin), which will not register on the lab work as free test, but is nonetheless easily taken up in the capillary beds of different tissues.

This information is from http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83686 This is an awesome article btw.

So, this explains why my bio avail test was almost as high as my total test. I hope this makes sense, and it certainly is nice to know I don't have low AR receptor density and/or low SHBG levels!
 
That makes a lot more sense. Wow, was I wrong there, Bioavailable =/= Free. (and it was so easily available too with a google search!). Good job looking into this, GS.
 
bio vs free

GSRacer said:
I recently posted some lab work that showed a high total testosterone level due to exogenous supplementation (4890ng/dL) . Included in the results was a reading on "bio avail" testosterone. This number was 4157 ng/dL, which seemed very high relative to total test. I mistakenly thought at first that bio avail test is equivalent to "free" test. Free test represents all the testosterone in your blood that is not bound to SHBG (http://en.wikipedia.org/wiki/Sex_hormone-binding_globulin), and is thus available for use. Bio avail test is actually a more accurate reading of how much testosterone is available for use by your tissues, because there is a significant amount of testosterone that is bound very lightly by Albumin (http://en.wikipedia.org/wiki/Albumin), which will not register on the lab work as free test, but is nonetheless easily taken up in the capillary beds of different tissues.

This information is from http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83686 This is an awesome article btw.

So, this explains why my bio avail test was almost as high as my total test. I hope this makes sense, and it certainly is nice to know I don't have low AR receptor density and/or low SHBG levels!
Click to expand...

You are exactly right my man. I thought someone had said that bio and free test were the same so I took a look.[SIZE=-1] Free testosterone measures the free fraction, bioavailable testosterone includes free plus weakly bound to albumin. Thank you for being such an incredible contributor here. Makes me want to keep coming back.[/SIZE]
 
yes very good work my man ! The writing I had read had said that bio - available test was the same as free test , just goes to show you have to look into things more throughly. Being on this board is like going to school - GEAR school. lol
 
You are a skier and you never heard of Lindsay Vaughn? :)
 

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jerseydevil said:
You're right. I didn't catch the misspelling from the original post, and I Googled Lindsay Vaughn and the pic I posted came up, lol.
Click to expand...

She's hot, and a great skier. But a total bitch IRL (apparently).

She had a bad crash in Feb. I'm amazed she can even bone Tiger. Maybe he just likes her company...
 
Gsracer. Your one of the lucky ones. Gifted genetics. My shbg is always low. My free test is almost always 3-5 percent of my total test. I got a lot of bound test in me lol..
 
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