Looking for some more insight on Proviron. I have heard pros and cons about Proviron. I’m 40 years old. I have tried mostly everything out there except this compound. I did my research on it, and am on the fence weather or not to give it a try.
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Proviron Testimonials
- Thread starter Jaxed42
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Mast and proviron are multipurpose and adaptable to just about any protocol as an all around clever and flexible benefactor. Truly!
Mast or proviron should/could be a requirement much like how people promote the idea being supper necessary to run AI's with each cycle/blast (which I agree with, dose depending).
When running proviron or mast in tandem with test and/or TRT especially for us older lions, I can't even begin to explain the complimentary effects and how its "equivalent to adding a turbo or twin turbo to someone's engine block".
The beauty is, users don't need much if the price of mast or proviron concerns them, 200mgs a week is plenty or mast, even 100-150mg with matstE, or 50-75mgs of PROVIRON..
People spend double that amount on protein powder and other sups, even triple.. Yet when its come to our sense of well being people over look proviron. I run it just about all year, and it will not effect lipids or shut you down. (I'm on TRT)
People need to get the idea that mast is a hardening drug, finishing agent, best used when lean out of there heads ( within reason tho), all of that applies to a complete different use and purpose.
www.PuritySourceLabs.ru Proviron
(A must have in your arsenal)
PSL Proviron Review
So, the discussion has came about many times over in regards to depression, insomnia, aggression, anxiety or other sides when on cycle/blast when utilizing Trenbolone..
Let's discuses Trenbolone and one compound that can help assist with side effects that can be unbearable for most, especially anxiety while using Trenbolone..
Please allow me to illustrate one of the most shrouded and seldomly discussed drugs in the whole anabolic circuit, one of the most underrated/pronounced effects ever
that somehow has failed to be discussed upon the masses, or misunderstood at best...Proviron!
"Proviron" Mesterolone
Most of you that have ever took the breakfast of champions "Methandrostenolone", That's right, I'm talking about Dbol.
What's the most apparent and conspicuous effects that takes place while taking Dbol?
If you were about to say the "sense of well-being" than your correct.
One of the most profound and desirable effects that we can have during a cycle..
Now, how about after a cycle like during PCT, Or for longer cycle/blast duration's when we feel fatigued?
One of the greatest characteristics about Proviron is it's "Antidepressant" properties.
With this being said, when it was first developed it was widely utilized in treatments for Bi-polar,OCD and Anxiety. As we know that depression is basically a chemical imbalance that comes about through the "Signaling" between receptors.
Proviron improves the quality of the "channels" that the cells use to communicate and interact, chitter chatter so to speak. Thus, a similar effect with Dbol where it drastically improves the sense of well being in users.
Much like Antidepressants, SSRI (Selective serotonin re-uptake inhibitor, and/or,SNRI (Serotonin-nor-epinephrine-uptake inhibitor)
What I'm about to share is a double blind study that clearly shows undoubtedly astonishing results in the patients! An other great reason to consider this compound.
Why Proviron is underestimated, the world may never know..
Tren is the compound that's well known for having a love-hate relationship with most users. Most will deem it a necessary evil. But, in fact it doesn't have to be classified as evil after all.
Here I will introduce some clinical studies that have been conducted with a compound most commonly known as Proviron-trade name (Mesterolone).
This agent possesses some amazing characteristics with Antidepressant properties, as well Anti-anxiety.
It works by also metabolizing and being recognized through the endocrine as (other) a neurosteroid, effectively functioning as a so-called proneurosteroid (testosterone is also recognized as one)..
These steroids synthesized in the brain much like a Nootropic (Proviron especially) and have effects on brains function..
In addition to their actions on neuronal membrane receptors improving the quality of the channels that cells use to communicate and interact.
Proviron/or Masteron (Masteron can be utilized due to it's targeting similarities)
Proviron (mesterolone) will exert inhibitory actions on neurotransmission, acting as potent positive allosteric modulator of the GABA receptor, this is crucial concerning Tren-Insomnia as healthy function levels of GABA will produce a stable sleep state/environment for rest
and displays in no particular order; antidepressant, stress-reducing, feeling warm/fuzzy/rewarding, pro-social, anti-aggressive (huge consider tren sides), pro-sexual, sedative/pro-sleep, cognitive-memory improvement..
The list literally goes on!
Where does this apply with Tren?
It can assist all the way around with individuals who are sensitive or not with trenbolone.
From the social aspect, overwhelming sense of anxiety, lack of sleep, basically everything stated above that may apply with the usage of trenbolone and the onset of its unwanted side..
In addition to this information an individual can also utilized masteron (Drostanolonein) in conjunction with Proviron (substituting one for the other), running both concurrently may yield a great synergetic effect, each compound will compliment one an other.
Further more Proviron is a DHT derivative. DHT compounds assist with hardening of the physique, lack of water retention, increased sex drive..
Hardening of the physique and lack of water retention go hand in hand. Proviron assists with this, the body recognizes proviron as a DHT, This causes a direct hardening affect on the muscle tissue much like Masteron displays..
The increase in muscle dryness/density comes from a reduction in free/circulating estrogen levels, because proviron has the ability to 'latch-on' to the estrogen binding enzymes, It competes so to speak for its position, it does this aggressively..
Thus, decreasing water retention. Also the the lack of aromatization and the fact that the drug is prototypical androgen, causes a significant shift in the body’s estrogen/testosterone ratio.
As proviron's atomic structure it is incapable of forming estrogen. It also has properties with AR's..
Increasing the AR expression, proviron/DHT uptake to further increase AR expression, repeating this process over and over...
This allows other AAS compounds to appear to be amplified with there effects, assisting the compounds -
"What does this mean"?
Proviron can be a master key so to speak, having multiple functions - It binds aggressively to the AR's and SHBG, thus it can/may increase the activity of other AAS..
After years of studies on just Mesterolone it proved to have hardly any real effect on health markers..
It's none suppressive and only slightly decreased LH and FSH in users that had naturally HIGH T levels above the norm, and brought them down slightly, yet still in the higher percentile..
This was used for YEARS on end... Using any AAS for years on end is not advised, this is just an outline of what could happen in the event of.
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Functions concerning the neurotransmitter/receptor and how it works:
Citation
Database: PsycINFO
[ Journal Article ]
A comparison of the antidepressant effects of a synthetic androgen (mesterolone) and amitriptyline in depressed men.
Vogel, William; Klaiber, Edward L.; Broverman, Donald M.
Journal of Clinical Psychiatry, Vol 46(1), Jan 1985, 6-8.
Abstract
26 depressed male outpatients were randomly assigned to 14 wks of treatment with either mesterolone or amitriptyline in a double-blind parallel treatment design. Ss completed the Hamilton Rating Scale for Depression and a symptom checklist each week. Findings reveal that the drugs were equally effective in reducing depressive symptoms. Mesterolone produced significantly fewer adverse side effects than amitriptyline and did not produce hypomania or tachycardia, recognized side effects of amitriptyline. (10 ref) (PsycINFO Database Record (c) 2013 APA, all rights reserved)
Methods Find Exp Clin Pharmacol. 1984 Jun;6(6):331-7.
The effects of mesterolone, a male sex hormone in depressed patients (a double blind controlled study).
Itil TM, Michael ST, Shapiro DM, Itil KZ.
Abstract
Based on computer EEG (CEEG) profiles, in high doses, antidepressant properties of mesterolone, a synthetic androgen, were predicted. In a double-blind placebo controlled study, the clinical effects of 300-450 mg daily mesterolone were investigated in 52 relatively young (age range 26-53 years, mean 42.7 years) male depressed outpatients. During 6 weeks of mesterolone treatment, there was a significant improvement of depressive symptomatology. However, since an improvement was also established during the placebo treatment, no statistically appreciable difference in the therapeutic effects of mesterolone was established compared to placebo. Mesterolone treatment significantly decreased both plasma testosterone and protein bound testosterone levels. Patients with high testosterone levels prior to treatment seem to have had more benefit from mesterolone treatment than patients with low testosterone levels. The degree of improvement weakly correlated to the decrease of testosterone levels during mesterolone treatment.
Information confirming no HTPA shutdown/suppression during PCT
These are some research articles that may justify the use of low/moderate dose Proviron during PCT:
AAKVAAG, A., and S. B. STROMME. "The effect of mesterolone administration to normal men on the pituitary-testicular function."Acta endocrinologica77.2 (1974): 380-386.
ABSTRACT
Mesterolone (1α-methyl-5α-dihydrotestosterone) has been given to 10 normal men, age 24–27 years, and the effect on the plasma levels of ICSH, FSH and testosterone has been studied.No effect on the plasma levels of ICSH and FSH could be detected. After 4 weeks on 75 mg mesterolone per day a significant (P < 0.01) drop in the mean value for plasma testosterone level was observed, 5.2 to 4.0 ng/ml. After another 4 weeks on 150 mg mesterolone per day a further decrease to 3.5 ng/ml was found.During mesterolone administration the protein binding of testosterone in plasma was significantly reduced, and it appeared that the level of free (non-protein bound) testosterone in diluted plasma remained unchanged, 0.37 and 0.41 ng/ml, before and after mesterolone administration respectively.The results suggest that mesterolone given in doses of 75 and 150 mg/day to normal men does not suppress the pituitary ICSH production or the testicular testosterone production
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GORDON, R.D., THOMAS, M.J., POYNTING, J.M. and STOCKS, A.E. (1975), Effect of Mesterolone on Plasma L.H., F.S.H. and Testosterone. Andrologia, 7: 287–296. doi: 10.1111/j.1439-0272.1975.tb00942.x
Summary
It has been claimed that orally administered mesterolone, unlike l7a-methyl testo- sterone, does not suppress endogenous gonadotrophins and testesterone. To investi- gate this, both drugs were administered, in turn, to four normal men and plasma te- stosterone, L.H. and F.S.H. were measured serially. Mesterolone administration was associated in all four subjects with significant and similar falls in plasma testosterone, but significant suppression of gonadotrophins took place in only two of them. Any changes which occured were apparent by the end of the first week of therapy. Administration of half the dose of 17a-methyl testosterone to the same four subjects caused significant suppression of testosterone in each and suppression of one or both gonadotrophins in each.
In longer term studies in patients (5-30 months) involving serial measurements at intervals of one to two months, there was evidence of significant suppression of L.H. and F.S.H. by 17a-methyl testosterone, but not by mesterolone, which was clinically a less effective androgen.
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WANG, C., BURGER, H.G., de KRETSER, D.M., DULMANIS, A., HUDSON, B., KEOGH, E.J. and SUTHERS, M.B. (1974), Effect of Mesterolone on Serum FSH, LH and Plasma Testosterone in Normal Men. Andrologia, 6: 111–117. doi: 10.1111/j.1439-0272.1974.tb01604.x
Summary
To determine whether the claim that mesterolone, an orally active androgen, does not cause suppression of gonadotrophin secretion, two groups of five normal men were treated with 100 and 200 mg. daily respectively for 7 days. Serial measurements of serum FSH, LH and plasma testosterone were made on samples taken at 15 minute intervals over 2 hr both before and during treatment. Modest falls in FSH, LH and testosterone levels were observed in both groups, the percentage suppression being 21% and 18% for FSH, 19% and 15% for LH and 9% and 8% for testosterone at the lower and higher dosage levels respectively.
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200mg is a far greater dose than I would deploy during PCT (50mgs is ideal). From these studies and other articles we see have read, it's clear that there is almost minimal/no influence on the HTPA, any effect would be absolute minimal and negated by other appropriate compounds used during that period (HCG, Aromasin, Nolvadex and HGH)...
Team PSL supervisor
Vision
__________________________
Just an addition to the above read!
also....
Proviron will NOT suppress LH or FSH and will even provide your body with more free testosterone due to the fact that it binds "AGGRESSIVELY" to SHBG (lowering levels)....With this said, your total test probably may not increase much, however that's not what's important, your Free-T is the ticket..
Your FREE T will INCREASE 5-10 FOLD.. Its freed from bound test ultimately allowing test to act in its original course of action, in lieu of being bound!
If you're experiencing excessive sweating at night from Trenbolone you may want to consider limiting yourcarbs in the evening,
this tends to help because the body is in a state of thermogenesis so there's a slew of activity taking place, Its known as "thermoregulation" as an integral part of sleep homeostasis...
Your body will warm itself up, however during thermgenesis from powerful andros like tren, carbs fuel this process 10 fold...
Limit your carbs and my prove to be effective..
Last but not least, here's some more information that can provide you with achieving an environment that will assist with more FREE-T..
"Proviron with Winstrol"
Here's a study on proviron and winny together.
How winny and proviron will make your cycle kick ass!
Really, only a very small amount of Testosterone exists as “free” testosterone. Free test is testosterone that capable of binding to the Androgen Receptor,
which is where all the rest of the magic happens, and allows for the following benefits:
-Enhanced growth factor activity (e.g. GH, IGF-1, etc.)
-Enhanced activation of myogenic stem cells (i.e. satellite cells)
-Enhanced myonuclear number (to maintain nuclear to cytoplasmic ratio)
-Enhanced protein synthesis
-New myofiber formation
Testosterone binds at around 45% to what is known as Sex Hormone Binding Globulin (SHBG), and about another 53% binds to proteins (albumin).
The rest exists in a “free” state (about 2% if you did your math).
Different variations of steroids also differ in the way in which they bind to proteins.
If one could unbind testosterone from SHBG by even a small percentage, it could make a big difference in the way that testosterone or other AAS exert their anabolic effects.
Studies show that when testosterone is unbound from SHBG the “free” test does in fact exert greater effects than total T. As the following studies support:
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Demisch K, and Nickelsen T. Distribution of testosterone in plasma proteins during replacement therapy with testosterone enanthatein patients suffering from hypogonadism Andrologia 1983;15 Spec No:536-41.
Gandar R. Interpretation of the blood level of a steroid Rev Fr Gynecol Obstet 1985 Aug-Sep;80(8-9):635-40.
Legrand E., et al. Osteoporosis in men: a potential role for the sex hormone binding globulin Bone 2001 Jul;29(1):90-5.
Longcope C., et al. Diet and sex hormone-binding globulin. J Clin Endocrinol Metab 2000 Jan;85(1):293-296.
Valero-Politi J, and Fuentes-Arderiu X. Within- and between-subject biological variations of follitropin, lutropin, testosterone, and sex-hormone-binding globulin in men. Clin Chem 1993 Aug;39(8):1723-1725.
Proviron(1-Methyl Dihydrotestosterone) has been shown to bind with SHBG much more readily than test.
Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate,
as well as to sex hormone-binding globulin.
Saartok T, Dahlberg E, Gustafsson JA.
It is unclear whether anabolic steroids act on skeletal muscle via the androgen receptor (AR) in this tissue, or whether there is a separate anabolic receptor.
When several anabolic steroids were tested as competitors for the binding of [3H]methyltrienolone (MT; 17 beta-hydroxy-17 alpha-methyl-4,9,11-estratrien-3-one) to the AR in rat and rabbit skeletal muscle and rat prostate,
respectively, MT itself was the most efficient competitor.
1 alpha-Methyl-5 alpha-dihydrotestosterone (1 alpha-methyl-DHT; mesterolone) bound most avidly to sex hormone-binding globulin (SHBG) [relative binding affinity (RBA) about 4 times that of DHT].
Some anabolic-androgenic steroids bound strongly to the AR in skeletal muscle and prostate [ RBAs relative to that of MT: MT greater than 19-nortestosterone ( NorT ; nandrolone ) greater than methenolone (17 beta-hydroxy-1-methyl-5 alpha-androst-1-en-3-one) greater than testosterone (T) greater than 1 alpha-methyl-DHT]. In other cases, AR binding was weak (RBA values less than 0.05): stanozolol(17 alpha-methyl-5 alpha- androstano [3,2-c]pyrazol-17 beta-ol), methanedienone (17 beta-hydroxy-17 alpha-methyl-1,4-androstadien-3-one), and fluoxymesterolone (9 alpha-fluoro-11 beta-hydroxy-17 alpha-methyl-T). Other compounds had RBAs too low to be determined (e.g. oxymetholone (17 beta-hydroxy-2-hydroxymethylene-17 alpha-methyl-5 alpha-androstan-3-one) and ethylestrenol (17 alpha-ethyl-4- estren -17 beta-ol). The competition pattern was similar in muscle and prostate, except for a higher RBA of DHT in the prostate. The low RBA of DHT in muscle was probably due to the previously reported rapid reduction of its 3-keto function to metabolites, which did not bind to the AR [5 alpha-androstane-3 alpha, 17 beta-diol and its 3 beta-isomer (3 alpha- and 3 beta-adiol, respectively)]. Some anabolic-androgenic steroids (only a few synthetic) bound to SHBG (1 alpha-methyl-DHT much greater than DHT greater than T greater than 3 beta-adiol greater than 3 alpha-adiol = 17 alpha-methyl-T greater than methenolone greater than methanedienone greater than stanozolol). The ratio of the RBA in rat muscle to that in the prostate (an estimate of the myotrophic potency of the compounds) was close to unity, varying only between about 0.4 and 1.7 in most cases.(ABSTRACT TRUNCATED AT 400 WORDS)
Skalba P, Korfanty A, Mroczka W, Wojtowicz M. Related Articles
[Changes of SHBG concentrations in postmenopausal women]
Ginekol Pol. 2001 Dec;72(12A):1388-92. Polish.
Variations of sex hormone-binding globulin in thyroid dysfunction.
Brenta G, Schnitman M, Gurfinkiel M, Damilano S, Pierini A, Sinay I, Pisarev MA.
Department of Endocrinology and Metabolism, French Hospital, Buenos Aires, Argentina. brenta@cnea.gov.ar
With the aim of understanding the variations of the levels of sex hormone-binding globulin (SHBG) in thyroid dysfunction, we studied the influence of factors that also modify SHBG, such as menopausal status, age, and body mass index (BMI) in women with hypothyroidism and hyperthyroidism, both overt and subclinical. Statistical analysis was performed by means of analysis of variance (ANOVA), stepwise multiple regression, and partial correlation. The ANOVA showed a significant statistical difference among the means of SHBG of all groups (p<0.01). The difference was due to the group that included hyperthyroid women. Multiple regression analysis showed that the main factors influencing SHBG were BMI and age, except for the hyperthyroid group, where the most important independent variables were triiodothyronine (T3) and thyroxine (T4). Partial correlation controlling the effect of BMI and age showed no association between SHBG and the other variables in all groups except for the subclinical hyperthyroid and hyperthyroid, where we found a significant association between SHBG and T4 and T3. The premenopausal or postmenopausal status did not modify SHBG levels. When the patients are taken as a whole, BMI, age, T4, and T3 all have an association with SHBG levels according to the multiple regression analysis.
Determinants of sex hormone-binding globulin blood concentrations in premenopausal and postmenopausal women with different estrogen status. Virgilio-Menopause-Health Group.
Pasquali R, Vicennati V, Bertazzo D, Casimirri F, Pascal G, Tortelli O, Labate AM.
Department of Internal Medicine and Gastroenterology, University of Bologna, Italy
Just a quote: 2) SHBG values are correlated positively with estradiol and negatively with insulin and testosterone concentrations, but the predictive value of these variabiles on SHBG appears to be different in premenopause and postmenopause; Here is a fun little fact:the level of SHBG can also be influenced by other factors. There is a direct relationship between the level of estrogen and thyroid hormones and the level of SHBG. Estrogen goes up, SHBG goes up. Estrogen goes down SHBG goes down. Same for Thyroid hormones triiodothyronine (T3) and thyroxine (T4). Also, there is a relationship with diet and insulin, but that is something I will save for later.
Higher androgen levels due to AS administration has been shown to considerably lower levels of SHBG as well. The AaS Winstrol (stanozolol) was shown in a 1989 study to lower levels of SHBG by 50% after oral administration.
Sex hormone-binding globulin response to the anabolic steroid stanozolol: evidence for its suitability as a biological androgen sensitivity test.
Sinnecker G, Kohler S.
Department of Pediatrics, University of Hamburg, West Germany.
Both the androgen-induced decline in serum sex hormone-binding globulin (SHBG) levels during puberty and the anabolic effect of exogenous testosterone are absent in patients with androgen insensitivity (testicular feminization). To determine whether the androgen-induced decline in serum SHBG could be used as a test of androgen sensitivity, we studied the effect of the anabolic-androgenic steroid stanozolol (17 beta-hydroxy-17 alpha-methyl-5 alpha-androstano-[3,2-c]pyrazol) on serum SHBG in 25 control subjects, 3 patients with complete androgen insensitivity, and 4 patients with partial androgen insensitivity. Stanozolol was administered orally for 3 days (0.2 mg/kg.day); blood samples were taken before and 5, 6, 7, and 8 days after the beginning of the test for measurements of serum SHBG. The lowest value (i.e. the peak response) in each subject was used as the measure of the response to stanozolol. In the control subjects the mean nadir serum SHBG level was 51.6 +/- 5.9% (+/- SD) of the initial value (P less than 0.001). In the 4 patients with partial androgen insensitivity the nadir serum SHBG ranged from 73-89%, and in the 3 patients with complete androgen insensitivity it ranged from 93-97% of the initial value. Thus, the decrease in serum SHBG after short term administration of stanozolol reflects androgen responsiveness and, thus, may be used to differentiate patients with androgen insensitivity syndromes from those with other causes of male pseudohermaphroditism.
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Take away notes:
This was after oral administration, so I am not sure that I can extrapolate the data to injectable as well.
SHBG is made in the liver so even an injectable winny would have to be processed there, albeit slower, due to the slower release of injectable winny and it’s direct release into the bloodstream. That could possibly make it a little less effective in this regard.
In a nutshell: Proviron and Winny could provide the mechanisms to increase the value of other AS. Proviron would work because by binding to SHBG, it leaves hormone in a free state to bind to the AR. Proviron is a terrible Anabolic, but its affinity for SHBG would essentially “displace”other steroids from binding to SHBG.
Winstrol would work to reduce the overall amount of SHBG, thereby having the effect of freeing up hormone to bind to the AR. What a stack!
I hope you enjoyed the read....
Team PuritySourceLabs,
Vision
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Enhance the amount of circulating free testosterone:
Increase libido:
Combat estro sides:
Increase muscle hardness:
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More info..
Proviron can be added to any TRT protocol with or without Masteron (Drostanolone), exhibiting very similar properties.
EP's NEW TRT Blend / Testosterone enanthate 200mg/mL - Masteron Enanthate 200mg/mL - 400mg/mL
Why use the TRT blend? www.PuritySourceLabs.ru
Testosterone replacement therapy is as much an art as it is a science.
www.Euro-Pharmacies.net understands this concept this is why EP has designed and engineered the most sought-after ratio of hormones on the anabolic market today.
Through the treatment of Testosterone replacement therapy (TRT) one should be given based on symptoms instead of just blood values.
If you have no energy, gain fat easily, having trouble putting on muscle, have a low libido, and suffer from depression, you may need TRT.
Especially if you feel this after a cycle/blast with a so-called successful "PCT"..
(Blood work should be taken to see if you are on the low end of the T spectrum)
::CLICK HERE TO LEARN WHERE TO GET BLOOD WORK AND HOW TO DO IT::
Some benefits of this TRT stack may come rather quickly, such as increased libido as this may/can improve within weeks,
as can depression subsiding, loss of body fat and an increase in muscle and a overall sense of well being! www.PuritySourceLabs.ru
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a class of hormone replacement therapy in which androgens, often testosterone, are replaced (and can be utilized for cruises between cycles/blasts). ART is often prescribed to counter the effects of male hypogonadism. It typically involves the administration of testosterone through injections of Testosterone. www.PuritySourceLabs.ru
ART is also employed after a cycle/blast for those that wish to stay "ON" to lessen the effects of being shut down, as user may notice changes caused by a relative decline in testosterone: TRT is employed to avoid fewer erections, fatigue, thinning skin, declining muscle mass and strength, more body fat. Dissatisfaction with these changes causes some users to lose appetite, and most gains made during their cycle. Most of all, TRT/cruise is utilized to help keep that healthy state of well-being while giving their body a rest between cycles/blasts..
The addition of Masteron in the blend is partially due to its anti-estrogen properties, and we say this for great reason. Masteron is a derivative of DHT (dihydrotestosterone) and does not convert to estrogen through the means of aromatization. It is thought that the anti-estrogenic properties of Masteron may be in part to do with either an inhibition in some way of the aromatase enzyme or an interaction with estrogen itself in a way which blocks receptor binding of the estrogen.
Either way, it's a WIN-WIN situation this would put Masteron as a very useful tool for the AAS user and specifically for those that cruise on low "T" doses who wish to inhibit the conversion of T to estrogen -
by inhibiting the aromatase enzyme, Masteron would be in effect blocking the conversion of testosterone to estrogen by the aromatization pathway Yielding greater levels of Free usable test. (HIGHER FREE T LEVELS)
This would not only serve to marginally increase the amounts of active free testosterone in circulation (thus giving a greater effect of the testosterone during a TRT treatment or cruise)..Most TRT users report almost no need for AI's during this treatment with Low to moderate Testosterone ran concurrently with Masteron.
Average Testosterone Enanthate dosages are anywhere from 125mgs to 250mgs weekly, with just 200mgs a week of Masteron creating a match made in heaven, a complimentary duo!
(We suggest getting blood-work to reinforce these statements that are made with masteron assisting testE in this blend) ::CLICK HERE TO LEARN WHERE TO GET BLOOD WORK AND HOW TO DO IT::
For those on TRT or who blast & cruise, this blend is truly the master of all. Leading the way with what would probably be consider the BEST blend ratio mix with hormones serving numerous functions, virtually to many to list.
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Dosages:
They can range from 400mg a week up too 1000mg. One unique property with the cocktail is that you don't need much and 1mL weekly could prove to be a perfect dosages for just about anyone, especially those who are new to using low to moderate dosages, of those who are beginning their TRT therapy.
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Chemical Name:Testosterone, Drostanolone
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Active time: Approx 21 days
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Blood work below from personal study in Sept 2018 on 200mg Pharma script Testosterone Cypionate with Masteron (Drostanolone) and Proviron (Mesterolone)
As many of you know I blast & cruise, more blasting than cruising with switch hitting.. I had blood work that was expected to be pulled from my Doc, he actually forgot and I had to remind him, it worked out well because I wanted to come off for a bit and do a little small cruise (6 weeks'ish) and give my CNS a moment to recoup as well as giving my REC's a brake..
I figured this would also be a great opportunity to take advantage of Masteron and Proviron used in conjunction with my TRT.. For the following reasons to keep libido strong, depression at a low at the same time optimizing the most out of my TRT dosage..
The addition with Proviron & Masteron is that it's a useful tool for the TRT user and specifically for those that cruise on low "T" doses who wish to inhibit the conversion of T to estrogen. By inhibiting the aromatase enzyme, Masteron would be in effect blocking the conversion of free testosterone to estrogen by the aromatisation pathway Yielding great levels of Free usable test. This would not only serve to marginally increase the amounts of active free testosterone in circulation (thus giving a greater effect of the testosterone during a TRT treatment or cruise).. With this said, I was just using 200mgs Script test-cyp E7D (with script adex .5 E3D) and Masteron-200 E7D and proviron at 50mg ED this ultimately created a match made in heaven, a complimentary duo!
Bloods were pulled 3 days after last pin and I was fasted and the panel was a sensitive essay (I wanted to see if my BS levels would effect estrogen total serum by way of estrone elevation due to fasting).. I have BS issues along with a family history of diabetes, the serum levels were extremely high and I doubt there was cross-reactivity of anything else due to the fact that E2 was low.. Being in a fasted state seems to be the culprit..
Further more, people tend to put blood serum numbers in a standard range of expectancy.. I've always advocated that I'm a slow/low metabolizer, even at 200mg which is the high end of TRT treatment and I barely scraped the high end.. It proves that this truly is NOT a one size fits all..
My closing comments : Libido was great, appetite was strong and I have no complaints, my sense of well-being was on point..The extreme low SHBG levels IMO are directly associated with the mast/prov, thus the result of low estro and higher free T..This can explain why I continued to feel great even after lowering my T dosage significantly..
I will continually use Mast and/or Proviron with every cruise I do!
Outstanding products...
There's an Easter egg here that's hidden inside of all of this, it's something I don't want people to miss.
This goes to prove that you really don't need much testosterone.. People don't need to chase a high total serum number in order to feel confident and reassured, when people are expecting numbers in or around the 3k + range and they believe that this is where you need to be in order to make the most progress, this is simply false and misleading.
Stop chasing total serums and focus on free test levels.. People can have 3000 of bound test and that doesn't mean anything, in fact that testosterone is useless if your FREE T ratios are low..
Users could incorporate compounds that are complementary with freeing up bound testosterone into more bioavailable testosterone such as Proviron (Mesterolone) - Masteron (Drostanolone) or Winstrol (Stanozolol)
Think of the example of speakers with an amplifier. Somebody could have 3000 watts being pushed into a set of speakers, yet clarity and distortion is a huge factor hindering quality with actually just sounding noisy. Compared to someone that has 500 watts of real quality true wattage with other components added for a smoother current and flow, better power source signaling while it sounds and out performance the counter-part that was sitting at 3000 watts. The quality option with purity vs. total raw out-put added life to the sound, do the same for the signaling within your body.
The conclusion here is to free up your bound testosterone levels, increase FREE T and let all of the other compounds be the workhorse in your cycles or blast or simply your TRT protocol..
Know how to optimize your testosterone levels so they can work best for you.. It's not about quantity but rather quality..
I would rather have several hundred work horses, compared to 3000 useless horses..
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Proviron "could" lower SHBG in some users
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Thank you for sharing this information. I started taking Proviron a week ago with my TRT 150mg Test E dose. Proviron makes me feel happy and gives me positive sence of well being. This in important to me since I have battled depression for 30 years. I refuse to be on an anti depressant that makes me hazy and all fu*ked up. Now with the help of ASF I have found my feel good med. I'm also more productive in the gym
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What is the typical time to remain on proviron? Can it be combined safely with turinabol (I'm assuming yes since you mentioned winny in the 1st post and little effect on health markers)
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The time that an individual is on it is really up to them, it's one of those drugs that can be a long-term treatment or it can be used for a cycle.
I have used it religiously. Long term with my trt. If I go a day or two without it, skipping incidentally, I do feel it. For myself when I say that it does have antidepressant like properties that's the gods honest truth.
I have been using nothing but my trt master and proviron and I just increased the dosages as I go with blasting and cruising, but I haven't blasted since the end of November
I love proviron. Love it. Makes everything better to me with every cycle I use it on.
And yes vision I agree with antidepressant quality, not because I have issues with that but I know proviron is actually prescribed in some countries for men with depression. Also is the only steroid I know that actually increases semen count and fertility.
I would run it year round if it wasn’t so damn expensive
And yes vision I agree with antidepressant quality, not because I have issues with that but I know proviron is actually prescribed in some countries for men with depression. Also is the only steroid I know that actually increases semen count and fertility.
I would run it year round if it wasn’t so damn expensive
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I have ran Proviron many times. Bayer & underground, I do not notice a lot from running it. Maybe a tad bit harder and vascular looking. Sex drive....meh, very unrewarding given the raving reviews. I have had blood work done on proviron and did not notice a drop in SHGB or increase in free test. I've used it for PCT, during cycle, on cruise.... I keep hoping it will work as good as people say, but it hasn't yet. Now, please do your own experiments because I can also say that I have just as much experience with Anavar and that doesn't do shit for me either. Now if I pop 25 mgs of Dbol for a week, my pumps are so intense my jaw locks up while chewing.
Note: My usual for Proviron is 75mgs / Day.
Note: My usual for Proviron is 75mgs / Day.
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This is my experience. Killed my sex drive. Tried multiple sources and doses. The end result was the same
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Man you're not kidding about the jaw pumps, I remember being in the car with my mother and my girlfriend coming back from Costco's and I was eating a bag of beef jerky.. that was my first jaw pump experience from dbol.
I recall being absolutely starving but I couldn't eat anymore.
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Would you gentleman be interested with running a mock version clinical test for us, and all the readers in the community? At the end of the day we rely on anecdotes, and with both of your experiences it truly outlines how everybody responds differently.
If I was able to make it happen, would you guys be interested in trying it again, and pulling some blood work, and also maybe holding on to a few tabs and sending them away for testing?
I would love to see the results with two individuals that have had bad experiences regardless of the brands, and giving it one more go with ruling out all factors.
I'll personally compensate you as well for the blood work cost?
Your feedback would be legit data and info for future readers to consider.
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I'm and a nootropic and feel-good kind of guy, I love feeling crisp, sharp and on point with clarity. Mentally and physically.
I love nootropics, and in my opinion this drug could be considered one.. but of course that's just my personal opinion.
This might be the FIRST time I've ever seen anything negative about provi. Anyone that knows me knows I absolutely LOVE it. I've told dozens of guys about it and EVERY one of them has thanked me that has tried it. I've been in the game awhile and only learned about it maybe 2 years ago. I really don't know how I did without it so long. It's been an absolute Godsend for my sex life. And I realize not everyone will have the same results- but 99.9% of guys will benefit from it imo. I won't be caught dead w/ out it- it's actually in w/ my vitamins now. My advice for op is try it, you'll like it- if not, I'll be shocked- HR
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This is most definitely one of the few times that I've seen some negative reports on it, there is another individual that posted on a community that it shut him down..
He was really adamant, and he swears that the quality was authentic, and if I'm not mistaken I believe he said it was tested, but don't quote me on that. But he did say for certain that it shut him down and he didn't do well on it at all.
But yet there's overwhelming data to support that it is not suppressive.
They literally collected data from people that were specifically running it and these were hundreds of hundreds of people in this particular study. And the only ones that displayed signs of suppression, was those that had naturally high levels of test, and it just budged their markers slightly down to what would be more in the normal ranges. But those in the normal ranges did not show any decrease at all.
Some other guy on pro muscle who was extremely difficult to speak with, very rude, condescending and berating, was advocating how it's absolutely awful on lipids.
But I didn't want to get into it with him, I have nothing to prove, and it's the internet at the end of the day. I forget his name but he was mean and he was not a nice person.
But I'm interested to see if both of these guys above would be willing to do some sort of mock study/science experiment for us.
After all this is one big science experiment and everybody's data and input matters.
What was your test dosage and what AI and AI dosage? I'm willing to bet your estrogen was already low and proviron gave you low estrogen side effects.
Have you had blood work to know what your estrogen normally runs with the test dosage and AI dosage you normally use?
cdubw44
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I am in the proviron does nothing for me category. Still have bags of it from years ago and no real change in free test on blood work. But mast on the other hand is freaking amazing for me.
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Sent from my moto g play (2021) using Tapatalk
Pete44
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I have never tried Mast or Provi but I am going to
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Man I can't live without either one of them.Vision laid it all out. I don't see many or any cons with proviron, or mast for that matter I run 1 or both majority of this year.
I truly give credit to mast and proviron for getting me through this setback that I had these past 7 months. They just compliment test so well, and it made me feel great when I was at my absolute worst. Now amplify that when you're on and firing on all cylinders, forget about it..
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Agreed .
Pete44
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Forgot about it lol
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200/200 E6D
