How your estrogen is affected is very personal. I'd recommend keeping a couple things on hand though (letro, ad ex, and aromas in) I would probably use a low does of asin right off the bat. Also prolactin I would personally use prolactrone right away and keep prami on hand. That said I would also recommend doing daily doses of tren. The more stable the tren stays, seems to be a big factor of how bad sides get.