Pappybay thanks for the response. What were you referring to when you said to take 10-12.5 mg EOD ? were you referring to the Clomid or the Exetremestane ? because the dr prescribed 50 mg of Clomid twice a week.
So please clarify for me, to my understanding i think your suggesting to take the clomid twice a week and then take 10-12.5 mg of the exetremestane EOD ???
Also i can't get the HCG from the dr until i go back in 6 weeks. so once i get it i will start with that.
Once last thing, its fine to take both the clomid and exetremestane right ?
I don't see a need to take both. I personally recommend taking anastrozole but that is personal preference. There is no need to take both clomid and Aromasin. Aromasin is the 12.5 EOD. Clomid would be the 50 but that sounds high to me. Since I have never used Clomid I honestly can not speak from personal experience.
Here is some more info on the topic. Hope this helps (can't remember where I got this info as it has been a long time.......)
AI= Aromatase inhibitor. It prevents the aromatase enzyme from acting on testosterone and turning the test into estrogen.
SERM= Selective Estrogen Receptor Modulator. These chemicals act on your estrogen receptors, not estrogen itself. SERMs prevent estrogen from exerting their cellular effects.
SERMs block estrogen from acting on certain sites in the body, while AIs prevent your body from synthesizing estrogen, two very different actions.
AIs are categorized into two types:
Type 1: Irreversible steroidal inhibitors such as exemestane form a permanent bond with the aromatase enzyme complex.
Type 2: Non-steroidal inhibitors (such as anastrozole, letrozole) inhibit the enzyme by reversible competition.
Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. By inhibiting aromatase they increase Testosterone and reduce Gynecomastia.
1. Letrozole (common brand name Femara) is a type 2 AI.
Letrozole has shown to reduce estrogen levels by 98 percent while raising testosterone levels. Usage above 2.5 mg/day is known to potentially temporarily kill sex drive. I can tell you that letro will KILL your sex drive!!!
Above 5mg/day for extended periods may cause kidney problems. I do not think this is a TRT option. Use only to reverse gyno.
SERM (Selective Estrogen Receptor Modulaters):
Are a class of compounds that acts on the estrogen receptor. A characteristic that distinguishes these substances from pure receptor agonists and antagonists is that their action is different in various tissues, thereby granting the possibility to selectively inhibit or stimulate estrogen-like action in various tissues
1. Tamoxifen (brand name Nolvadex).
In men, tamoxifen is sometimes used to treat gynecomastia which arises for example as a side effect of antiandrogen prostate cancer treatment.Tamoxifen is also used by bodybuilders to prevent or reduce drug-induced gynecomastia caused by the estrogenic metabolites of anabolic steroids.
2. Clomifene or clomiphene (brand name Clomid)
Clomifene acts by inhibiting the action of estrogen on the gonadotrope cells in the anterior pituitary gland. In response to low estrogen levels, follicle-stimulating hormone (FSH) release is increased. Clomid is used to bind the estrogen receptors in, thereby blocking the effects of estrogen, i.e., gynecomastia. It also restores the body's natural production of testosterone. It is used as a "recovery drug" and taken toward the end of a cycle.
SERD (Selective Estrogen Receptor Downregulator):
1. Fulvestrant (brand name Faslodex) It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor.