Ways to Combat Superdrol Lethargy?

[SloppyJ]

10mg is treating me nicely so I'm going to stick with this for a second.

 

[SloppyJ]

For everyone telling me 3mg of adex per week crashed my estro.... lel

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[Vision]

AAS use can do thos, especially SD or M1T because it's extremely aggressive can result in a decrease peak of plasma corticosterone concentrations by way of potentially disabling HSD-11B or 11B-HSD which are hosts of enzymes that catalyze the conversion of cortisone to active cortisol.. Almost inducing a state of adrenal fatigue by other methods of action, basically inducing adrenal fatigue like symptoms..You can experience this while on most AAS "especially" Trenbolone, drol and some pro-hormones that are mentioned (MT1/SD), there can be a slew of rather aggressive sides not only from it's toxicity to the liver but through this other indirect course of action yielding a slew of undesired sides in "some" users....

I would suggest adding some DHEA with some sublingual vitamin b12 complex and take it from there.. Try and cut back on caffeine, in fact I would suggest extracting it from your daily life just for now..

An other suggestions, you may want to add some low to a moderate dose of GHRP-6 and/or Hexarelin, these peptide both act in a similar mechanisms and have been known to increase the release of ACTH which can improve the serum plasma levels with cortisol, restoring it to a health functional state, hindering any "oral AAS" related sides that may be present by way of adrenal fatigue like symptoms..

AAS, love-hate relationship with many trade-offs!

Also, maybe toss in a DHT.. Below is some info I posted some time back, inside the corss post you may find some helpful info on why DHT's may assist with you situation..

____________________________

The paradox with 3 of the 4 hormones mentioned (test,mast and proviron) they are essentially the most favored when it concerns that "feel good effect" that we look for when running compounds, now at this moment each one contradicts what you're attempting to achieve (feel good and grow)..Therefore like mentioned in post #3, I'm leaning heavily on cortisol for a good reason!

Let's look at your supra-physiological dosages of Testosterone (which has 3 mechanisms of action,1-testosterone, 2-conversion to estro, 3-conversion to DHT) and your other compounds like mast/proviron..Basically, your reaction with these compounds/hormones by way of exogenous sources along with their aggressiveness as a potent hormone (DHT) and interplay's with E2 (by was of test conversion) all these can significantly decrease the corticosterone and ACTH response through its pathways, by initiating a response via the hypothalamus..

I'll include a study that explains more on how Dihydrotestosterone and it's derivative can potentially display some cross-reactivity that will disrupted corticolsteroids which may possess blocking properties of cortisol..In a nut shell, DHT's could possibly act somewhat as a cortisol "blocker" in sensitive users..End result, adrenal fatigue like symptoms!

Just my take, I'm no specialist..I'm just looking at things from a different approach, it may not be the most popular belief, but it's a start for answers.. Anyone else?
_________________________

J Neurosci. 2006 Feb 1;26(5):1448-56.
The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.

Lund TD1, Hinds LR, Handa RJ.
Author information

Abstract

Estrogen receptor beta (ERbeta) and androgen receptor (AR) are found in high levels within populations of neurons in the hypothalamus. To determine whether AR or ERbeta plays a role in regulating hypothalamo-pituitary-adrenal (HPA) axis function by direct action on these neurons, we examined the effects of central implants of 17beta-estradiol (E2), 5alpha-dihydrotestosterone (DHT), the DHT metabolite 5alpha-androstan-3beta, 17beta-diol (3beta-diol), and several ER subtype-selective agonists on the corticosterone and adrenocorticotropin (ACTH) response to immobilization stress. In addition, activation of neurons in the paraventricular nucleus (PVN) was monitored by examining c-fos mRNA expression. Pellets containing these compounds were stereotaxically implanted near the PVN of gonadectomized male rats. Seven days later, animals were killed directly from their home cage (nonstressed) or were restrained for 30 min (stressed) before they were killed. Compared with controls, E2 and the ERalpha-selective agonists moxestrol and propyl-pyrazole-triol significantly increased the stress induced release of corticosterone and ACTH. In contrast, central administration of DHT, 3beta-diol, and the ERbeta-selective compound diarylpropionitrile significantly decreased the corticosterone and ACTH response to immobilization. Cotreatment with the ER antagonist tamoxifen completely blocked the effects of 3beta-diol and partially blocked the effect of DHT, whereas the AR antagonist flutamide had no effect. Moreover, DHT, 3beta-diol, and diarylpropionitrile treatment significantly decreased restraint-induced c-fos mRNA expression in the PVN. Together, these studies indicate that the inhibitory effects of DHT on HPA axis activity may be in part mediated via its conversion to 3beta-diol and subsequent binding to ERbeta.

 

[hot rod]

this may sound crazy,but it works for me. taking 20 mg drol 1000 test e. also taking 20mg nolvadex. this has been the difference maker FOR ME. last time i took just drol and test,felt like shit,couldnt sleepetc. this time with the nolvadex no problems 18 days in. just saying its working great for me. good luck,bro

 

[Biggaintime]

High and low estrogen can share the same symptoms but sdrol is not the cause of high estrogen

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[Biggaintime]

Are you tired
Are you dragging ass
Are your eyes puffy
Are your eyes squinty like you smoked weed
When you look straight in the mirror are your ears disappearing because your cheeks are getting bigger
Do you feel more out of breath is your breathing heavier are you snoring at night
Are you bloated
Are you losing night wood
Having trouble getting hard nice big softy


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[Biggaintime]

Now low estrogen:
Are you tired
Do you feel like a zombie
Is your breathing clear and not heavy
Are your glasses or sunglasses sliding down your nose due to weight loss in your face.
Are you having trouble getting hard.
Getting hard at the wrong time never when you need it

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[Biggaintime]

Carbs, increase the carbs.

And get bloodwork. But in the meantime, increase the carbs and see if that helps. It did for me.

!

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[Biggaintime]

Some people just feel like shit on certain AAS like Adrol or Sdrol

The liver is resilient. It’s built to protect your body from toxins. If a bodybuilder is healthy, his liver can generally take some damage and heal back to normal after a cycle.

But you*NEED*to take some precautions:

You can’t use Superdrol for over 4 weeks.*ABSOLUTELY FOLLOW THIS.

Before your cycle, you should not have been drinking or taking other liver-toxic drugs.

And you should NEVER drink alcohol or take other drugs during your cycle. Even painkillers are stressful to your liver. Avoid them.

Increase your water intake. It helps your liver flush the toxins out.

If you abuse Superdrol… you WILL end up with liver damage. Be serious about this.*It can fuck up your life!

When your liver is exposed to stress, you may feel lethargic and a lack of appetite, which is usual when taking Superdrol.

Some bodybuilders take a supplement called milk thistle.*It accelerates the liver’s own detoxification. It’s not necessary, but may be a good addition if you want to protect your liver as much as possible.*Here is one of the most popular milk thistle brands.

However, I recently discovered an*even more powerful*liver protector.*Read my article on it if liver health is of your concern.

It spikes your blood pressure

Superdrol tends to increase your blood pressure a lot. Not good. Symptoms of extreme blood pressure are:

Relentless headache

Fatigue and confusion

Vision problems

Chest pain

Difficulty breathing

Irregular heartbeat

Blood in the urine

Pounding in your chest, neck, or ears

Personally, I may experience several of them when on a Superdrol cycle.

It messes up your blood lipids

You know the good blood cholesterol that is beneficial to your health?*Superdrol will lower your levels of it.

And you know the BAD blood cholesterol that causes blood clots, artery clogging, and increases your risk for heart attack, stroke and peripheral artery disease?*Superdrol will increase your levels of it.

Don’t even think about Superdrol if you’re prone to heart disease or already have bad blood cholesterol.



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[Biggaintime]

This is why you can only take it for 4 weeks. Anything with a high AA ratio is limited to 4 weeks or less. Never more.

Dead give away !

High AA ratios

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[SloppyJ]

BGT, I ended up dropping the superdrol a couple weeks ago. It was just too hard on me. Made my back hurt all of the time and I was going above and beyond what I needed to do for water intake, liver supps, etc...

I posted my bloods for all of the people at the beginning of the thread that were talking shit about how I crashed my estrogen on 3mg/wk of adex. I would like to lower it just a little more into the 60's range to feel better so I will slightly increase my adex dose. This blast is almost over but i will use this data for next time. I appreciate all of the helpful posts though.

 

[SloppyJ]

AAS use can do thos, especially SD or M1T because it's extremely aggressive can result in a decrease peak of plasma corticosterone concentrations by way of potentially disabling HSD-11B or 11B-HSD which are hosts of enzymes that catalyze the conversion of cortisone to active cortisol.. Almost inducing a state of adrenal fatigue by other methods of action, basically inducing adrenal fatigue like symptoms..You can experience this while on most AAS "especially" Trenbolone, drol and some pro-hormones that are mentioned (MT1/SD), there can be a slew of rather aggressive sides not only from it's toxicity to the liver but through this other indirect course of action yielding a slew of undesired sides in "some" users....

I would suggest adding some DHEA with some sublingual vitamin b12 complex and take it from there.. Try and cut back on caffeine, in fact I would suggest extracting it from your daily life just for now..

An other suggestions, you may want to add some low to a moderate dose of GHRP-6 and/or Hexarelin, these peptide both act in a similar mechanisms and have been known to increase the release of ACTH which can improve the serum plasma levels with cortisol, restoring it to a health functional state, hindering any "oral AAS" related sides that may be present by way of adrenal fatigue like symptoms..

AAS, love-hate relationship with many trade-offs!

Also, maybe toss in a DHT.. Below is some info I posted some time back, inside the corss post you may find some helpful info on why DHT's may assist with you situation..

____________________________

The paradox with 3 of the 4 hormones mentioned (test,mast and proviron) they are essentially the most favored when it concerns that "feel good effect" that we look for when running compounds, now at this moment each one contradicts what you're attempting to achieve (feel good and grow)..Therefore like mentioned in post #3, I'm leaning heavily on cortisol for a good reason!

Let's look at your supra-physiological dosages of Testosterone (which has 3 mechanisms of action,1-testosterone, 2-conversion to estro, 3-conversion to DHT) and your other compounds like mast/proviron..Basically, your reaction with these compounds/hormones by way of exogenous sources along with their aggressiveness as a potent hormone (DHT) and interplay's with E2 (by was of test conversion) all these can significantly decrease the corticosterone and ACTH response through its pathways, by initiating a response via the hypothalamus..

I'll include a study that explains more on how Dihydrotestosterone and it's derivative can potentially display some cross-reactivity that will disrupted corticolsteroids which may possess blocking properties of cortisol..In a nut shell, DHT's could possibly act somewhat as a cortisol "blocker" in sensitive users..End result, adrenal fatigue like symptoms!

Just my take, I'm no specialist..I'm just looking at things from a different approach, it may not be the most popular belief, but it's a start for answers.. Anyone else?
_________________________

J Neurosci. 2006 Feb 1;26(5):1448-56.
The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus.

Lund TD1, Hinds LR, Handa RJ.
Author information

Abstract

Estrogen receptor beta (ERbeta) and androgen receptor (AR) are found in high levels within populations of neurons in the hypothalamus. To determine whether AR or ERbeta plays a role in regulating hypothalamo-pituitary-adrenal (HPA) axis function by direct action on these neurons, we examined the effects of central implants of 17beta-estradiol (E2), 5alpha-dihydrotestosterone (DHT), the DHT metabolite 5alpha-androstan-3beta, 17beta-diol (3beta-diol), and several ER subtype-selective agonists on the corticosterone and adrenocorticotropin (ACTH) response to immobilization stress. In addition, activation of neurons in the paraventricular nucleus (PVN) was monitored by examining c-fos mRNA expression. Pellets containing these compounds were stereotaxically implanted near the PVN of gonadectomized male rats. Seven days later, animals were killed directly from their home cage (nonstressed) or were restrained for 30 min (stressed) before they were killed. Compared with controls, E2 and the ERalpha-selective agonists moxestrol and propyl-pyrazole-triol significantly increased the stress induced release of corticosterone and ACTH. In contrast, central administration of DHT, 3beta-diol, and the ERbeta-selective compound diarylpropionitrile significantly decreased the corticosterone and ACTH response to immobilization. Cotreatment with the ER antagonist tamoxifen completely blocked the effects of 3beta-diol and partially blocked the effect of DHT, whereas the AR antagonist flutamide had no effect. Moreover, DHT, 3beta-diol, and diarylpropionitrile treatment significantly decreased restraint-induced c-fos mRNA expression in the PVN. Together, these studies indicate that the inhibitory effects of DHT on HPA axis activity may be in part mediated via its conversion to 3beta-diol and subsequent binding to ERbeta.

Vision, solid info like always and definitely a different way to look at things. I still have enough superdrol to run another few weeks so if I ever get ballsy enough to do it again I will try all of this information out to see if it helps. I appreciate it brother.

 

[Biggaintime]

BGT, I ended up dropping the superdrol a couple weeks ago. It was just too hard on me. Made my back hurt all of the time and I was going above and beyond what I needed to do for water intake, liver supps, etc...

I posted my bloods for all of the people at the beginning of the thread that were talking shit about how I crashed my estrogen on 3mg/wk of adex. I would like to lower it just a little more into the 60's range to feel better so I will slightly increase my adex dose. This blast is almost over but i will use this data for next time. I appreciate all of the helpful posts though.

A lot if guys don't adrol because it makes them feel like shit too

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[Tall Deck]

I would NEVER use oral SD again. I think you'll find injectable SD to be very different when it comes to the lathrgy issues as well as the top dosage you can handle.

 

[zionoir626]

I tried some SD a few weeks ago at 10mgs....Mainly pre-WO,but for 4 days in a row,,break 2 days back on for 3 days...It caught up with me fast,granted my health is a bit off...Conclusion,10mgs is enough.....I plan to use it again but as a pre-WO only and not more than 3 days at a time without a break ...I find the pumps are un-beatable...However I have heard great things about injectable,and may try some soon...

 

[Vision]

There's some suggestions made here to use low dosage and only on pre-workout schedules.. I did a small experiment with this exact protocol back in the springtime.. it was the only time I felt half-decent on SD, low dose and it was not everyday..

 

[Tall Deck]

I'm on day 14 of Injectable S-drol, 35mg once per day, and so far so good. Much different than the tablets. After 13 days of the 30mg tabs, (one per day) I was litrerally on my AZZ!!! I could barely get up out of bed, and barely get up enough energy to take a 10 minute shower!! I was also missing days from work due to draggin' my feet so badly from the severe extreme lethargy. I fely like I had some major fatal disease. I couldn't go any longer than 13 days. I had to stop it completely despite taking injectable B-12 shots, NAC caps twice per day, a half gallon of water, and "TAD600-Glutatione" for the entire 13 days. So far, the injectable S-drol seems to be the ticket for me, but it's still early yet. Lets see how I feel in another ten days.

 

[HPM3TAL]

I'm on day 14 of Injectable S-drol, 35mg once per day, and so far so good. Much different than the tablets. After 13 days of the 30mg tabs, (one per day) I was litrerally on my AZZ!!! I could barely get up out of bed, and barely get up enough energy to take a 10 minute shower!! I was also missing days from work due to draggin' my feet so badly from the severe extreme lethargy. I fely like I had some major fatal disease. I couldn't go any longer than 13 days. I had to stop it completely despite taking injectable B-12 shots, NAC caps twice per day, a half gallon of water, and "TAD600-Glutatione" for the entire 13 days. So far, the injectable S-drol seems to be the ticket for me, but it's still early yet. Lets see how I feel in another ten days.

Damn, 35 mg a day. How are the strength and weight gajns? Oral sdrol has always made me feel like shit after a few weeks, so I'm looking forward to giving the injectable a try in about 8 weeks.

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[Wiseguy]

I tried Sdrol once and after a week on 20mg I had to stop. I take GW and b12, drink gallon and half water per day and nothing could keep me up. I would constantly fall asleep. Now I have been doing one hour of cardio daily for the past 20 years. I couldn't run for 15 minutes. I took several other suggestions and nothing worked for me so I stopped.

 

[SloppyJ]

Glad to see i'm not the only one that couldn't handle it despite doing everything in my power to mitigate the sides. I might try the injectable version but I'm not huge on pre workout injectables.

 

[Tall Deck]

Damn, 35 mg a day. How are the strength and weight gajns? Oral sdrol has always made me feel like shit after a few weeks, so I'm looking forward to giving the injectable a try in about 8 weeks.

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I don't pay much attention to the scale, so I'm not sure about weight gain, but I have no signs of bloating around face, ankles, nor hands. And my blood pressure hasn't raised. Sme strenght gains are beginning to take place, and after merely 14 days, that's saying a lot for me, because I don't get stronger very easily on anything, and I am 58 yrs old.

Glad to see i'm not the only one that couldn't handle it despite doing everything in my power to mitigate the sides. I might try the injectable version but I'm not huge on pre workout injectables.

I'm not into pre-workout injectables either. Guys rave about how they feel like an animal in the gym after 50-100mg of TNE pre-workout but I felt nothing from that.

I believe s-drol has an 8 hour half-life, so pinning once a day an hour before the gym should benefit during the post workout recovery phase too. So although I pin pre-workout with S-drol, I don't really just see it as boosting workout energy levels alone.