GarlicChicken Back to the Grind

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  1. #181
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    Quote Originally Posted by HFO3 View Post
    GC, your progress is movin along nice. John meadows is wealth of knowledge, I use his methods too, the guy is an Oracle


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    Thanks man. Yeah I love Meadow's info. He puts way more out there for free than anyone else that I've seen. His style seems to work really well for me too

  2. #182
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    Quote Originally Posted by HFO3 View Post
    Iím sure youíre felling like a new man. Way to go taking care of yourself here, High BP is nothing to play around with


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    Oh man I feel way better. I'd like it to even be a little lower, but I have the feeling is going to drop more over the next week while the telmisartan builds stable blood levels. Per the reading I've done, it takes about 10-20 days to reach peak plasma levels and make the most difference in BP. Gotta keep those kidneys healthy lol

  3. #183
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    Quote Originally Posted by GarlicChicken View Post
    I was around 145/78ish before, and on 40mg telmisartan daily I'm now sitting around 126/68. Stuff is working great for me
    Wow, perfect.

    Wish it worked that well for me . . .

  4. #184
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    Quote Originally Posted by malfeasance View Post
    Wow, perfect.

    Wish it worked that well for me . . .
    What dose are you on? Stuff works great for me. I was on beta blockers before and they were causing issues with keeping my heart rate too low

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    80 keeps me in the prehypertension range most of the time . . . on cycle

  6. #186
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    Quote Originally Posted by malfeasance View Post
    80 keeps me in the prehypertension range most of the time . . . on cycle
    Dang. Yeah I'm basically at a high cruise right now but not much raises my BP except tren and orals and I don't plan on really using orals anymore

  7. #187
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    Quote Originally Posted by GarlicChicken View Post
    I was around 145/78ish before, and on 40mg telmisartan daily I'm now sitting around 126/68. Stuff is working great for me
    Might be looking into this as my blood pressure has been a tad high. What, if any, sides have you experienced with telmisartan? I have zero experience with BP medication. What other options would you suggest? I remember you going over some pros amd cons of different BP medications before but can't find the old post.

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  8. #188
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    Quote Originally Posted by HPM3TAL View Post
    Might be looking into this as my blood pressure has been a tad high. What, if any, sides have you experienced with telmisartan? I have zero experience with BP medication. What other options would you suggest? I remember you going over some pros amd cons of different BP medications before but can't find the old post.

    Sent from my LG-H871 using Tapatalk
    Hey man. I typed out a nice detailed answer earlier but my app crashed and lost it lol.

    As far as sides I've had from the telmisartan, the only thing I've had is bad lethargy the first 4 days. Was falling asleep all day. After that it went away and I haven't had any at all since.

    So you have a few different types of BP meds. ACE inhibitors, which block the creation of angiotensin II. This reduces vasoconstriction and decreases sodium and water retention. Both of which lower blood pressure. The most common is lisinopril, and it usually the first prescribed medication after diuretics don't work. Typically started at 20mg daily. One fairly common side effect of ace inhibitors is a bad dry cough. Had to lookup what causes that, it's the increase in bradykinin levels, which is a vasodilator. It can also cause high blood potassium levels.

    ARBs, it angiotensin II receptor blockers, work by blocking the action of AT2 at the receptors. Telmisartan is an ARB that also has selective PPAR-y agonist properties. This has basically the same effect as ACE inhibitors by reducing sodium and water retention and increasing vasodilation. PPAR-y agonists also increase glucose and lipid metabolism, as well as blocking the maturation of new fat cells. These can cause the cough, but at a much lower instance than ACE inhibitors. They have much less adverse effects than ACE inhibitors. They're also a go to. Telmisartan is a more expensive one, but I'll take it for the PPAR action as long as it works.

    The next large class of meds are beta blockers. They work by blocking beta adrenergic receptors. This causes lessens the effects of stress hormones (epinephrine, norepinephrine) which reduces vasoconstriction and lowers heart rate as well. Most modern ones are selective b1 antagonists, and don't block b2 receptors as much. But a couple sides that are common are lethargy, reduced heart rate, and decreased fat burning. One big problem for me was the decreased heart rate. When I did cardio, I couldn't hardly get my heart rate above 120, reducing the effectiveness of cardiovascular exercise and making it to where it just didn't work my heart enough to make my heart healthier. Kinda defeated the purpose of cardio for everything but fat loss, as I'd prefer to get off meds if I can.

    There's a couple other types, alpha adrenergic blockers (flomax, terazosin, prazosin, etc) that are normally used to treat BPH. They don't typically lower my BP, they actually seem to make it higher. Plus I get really stuffy like I'm sick. Calcium channel blockers block the movement of calcium through voltage gated calcium channels, which reduces the contraction of arteries and cardiac muscle. They're also used as anti-arrhythmics to slow heart rate and reduce electrical misfirings. These are typically last line medications and normally used if there are electrical issues in the heart or patients that have gone into AFib.

    Short story long, either an ACE inhibitor or an ARB should be the first choice when starting bp meds. I went with telmisartan because of the additional positive effects it has, and ACE inhibitors give me a gnarly cough. Beta blockers should come after these, although some doctors (cough, VA) prefer these as first line. Which they shouldn't.

  9. #189
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    137/65 today on 80 mg telmisartan, but it has been higher recently. I have started doing more cardio recently, so maybe that is why it is lower today.

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    I know this isnt a telmisartan thread lol , but i took 20 mg telmisartan last night with dinner for the first time. I get random headaches, so of course I had a headache all night LOL. Gonna keep after it on 20mg for a week or two then move up if needed.

  11. #191
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    Quote Originally Posted by GarlicChicken View Post
    Hey man. I typed out a nice detailed answer earlier but my app crashed and lost it lol.

    As far as sides I've had from the telmisartan, the only thing I've had is bad lethargy the first 4 days. Was falling asleep all day. After that it went away and I haven't had any at all since.

    So you have a few different types of BP meds. ACE inhibitors, which block the creation of angiotensin II. This reduces vasoconstriction and decreases sodium and water retention. Both of which lower blood pressure. The most common is lisinopril, and it usually the first prescribed medication after diuretics don't work. Typically started at 20mg daily. One fairly common side effect of ace inhibitors is a bad dry cough. Had to lookup what causes that, it's the increase in bradykinin levels, which is a vasodilator. It can also cause high blood potassium levels.

    ARBs, it angiotensin II receptor blockers, work by blocking the action of AT2 at the receptors. Telmisartan is an ARB that also has selective PPAR-y agonist properties. This has basically the same effect as ACE inhibitors by reducing sodium and water retention and increasing vasodilation. PPAR-y agonists also increase glucose and lipid metabolism, as well as blocking the maturation of new fat cells. These can cause the cough, but at a much lower instance than ACE inhibitors. They have much less adverse effects than ACE inhibitors. They're also a go to. Telmisartan is a more expensive one, but I'll take it for the PPAR action as long as it works.

    The next large class of meds are beta blockers. They work by blocking beta adrenergic receptors. This causes lessens the effects of stress hormones (epinephrine, norepinephrine) which reduces vasoconstriction and lowers heart rate as well. Most modern ones are selective b1 antagonists, and don't block b2 receptors as much. But a couple sides that are common are lethargy, reduced heart rate, and decreased fat burning. One big problem for me was the decreased heart rate. When I did cardio, I couldn't hardly get my heart rate above 120, reducing the effectiveness of cardiovascular exercise and making it to where it just didn't work my heart enough to make my heart healthier. Kinda defeated the purpose of cardio for everything but fat loss, as I'd prefer to get off meds if I can.

    There's a couple other types, alpha adrenergic blockers (flomax, terazosin, prazosin, etc) that are normally used to treat BPH. They don't typically lower my BP, they actually seem to make it higher. Plus I get really stuffy like I'm sick. Calcium channel blockers block the movement of calcium through voltage gated calcium channels, which reduces the contraction of arteries and cardiac muscle. They're also used as anti-arrhythmics to slow heart rate and reduce electrical misfirings. These are typically last line medications and normally used if there are electrical issues in the heart or patients that have gone into AFib.

    Short story long, either an ACE inhibitor or an ARB should be the first choice when starting bp meds. I went with telmisartan because of the additional positive effects it has, and ACE inhibitors give me a gnarly cough. Beta blockers should come after these, although some doctors (cough, VA) prefer these as first line. Which they shouldn't.
    Thank you for the info! What would be the difference between increasing vasodilation and decreasing vasoconstriction? I get what each means, just seems to mean the same thing but said differently.
    Quote Originally Posted by Chuck Waygen View Post
    I know this isnt a telmisartan thread lol , but i took 20 mg telmisartan last night with dinner for the first time. I get random headaches, so of course I had a headache all night LOL. Gonna keep after it on 20mg for a week or two then move up if needed.
    If telmisartin increased vasodilation, I would think it would alleviate headache symptoms. Although, cialis does the same to some people.

    Sent from my LG-H871 using Tapatalk

  12. #192
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    Quote Originally Posted by HPM3TAL View Post
    .If telmisartin increased vasodilation, I would think it would alleviate headache symptoms. Although, cialis does the same to some people.
    Cialis gives me headaches at 20mg (a usual dose) but not at 5 mg.

  13. #193
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    Quote Originally Posted by Chuck Waygen View Post
    I know this isnt a telmisartan thread lol , but i took 20 mg telmisartan last night with dinner for the first time. I get random headaches, so of course I had a headache all night LOL. Gonna keep after it on 20mg for a week or two then move up if needed.
    It could I suppose, it is a listed uncommon side effect. I'd stick with it for a couple weeks if you can. That way you'll know if that is causing it or not. If it doesn't work, try a different ARB or an ace inhibitor

    Quote Originally Posted by HPM3TAL View Post
    Thank you for the info! What would be the difference between increasing vasodilation and decreasing vasoconstriction? I get what each means, just seems to mean the same thing but said differently.If telmisartin increased vasodilation, I would think it would alleviate headache symptoms. Although, cialis does the same to some people.

    Sent from my LG-H871 using Tapatalk
    Yeah basically it's the same thing lol. A true vasodilator will actually actively dilate vessels, whereas one that decreases constriction will passively do it I guess you could say.

    Yeah vasodilation can alleviate or cause headaches. Kinda depends on how it effects the individual and what causes their headache

  14. #194
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    Quote Originally Posted by malfeasance View Post
    Cialis gives me headaches at 20mg (a usual dose) but not at 5 mg.
    Same here

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    Not much to report here. Been on the road the last two days and even the hotels had the little gyms closed. So that was lame. Extra cardio for me tonight

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