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The discovery of selective androgen receptor modulators (SARMs) and other tissue-selective nuclear hormone receptor modulators that activate their cognate receptors in a tissue-selective manner provides an opportunity to promote the beneficial effects of androgens and other hormones in target tissues with greatly reduced unwanted side-effects.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896569/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896569/
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