Modafinil may reduce the blood levels of zolpidem, which may make the medication less effective in treating your insomnia. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.You should avoid the use of alcohol while being treated with zolpidem. Alcohol can increase the nervous system side effects of zolpidem such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Taking zolpidem with food may delay the onset of sleep. For faster sleep onset, zolpidem should not be taken with or immediately after a meal. This will make it easier for your body to absorb the medication. Talk to your doctor or pharmacist if you have any questions or concerns.
The strongest effect of modafinil on sleep architecture appears to be the increase stage N3 (slow-wave) sleep time. Slow-wave sleep was significantly higher in the modafinil group and more than double that in placebo at all time points. From a clinical perspective, this effect may also be particularly relevant.Modafinil definitely affects the dopamine system and dopamine will make you more alert, and also more interested in things," he says. "It affects norepinephrine which can again make you more alert and better able to focus, and it also
affects histamine which can keep you awake.In trials on healthy people, modafinil allowed users to stay up for
almost two days while remaining nearly as focused, alert and capable of problem-solving as the well-rested. After eight hours of sleep, Garreau writes, users can rise and go another 40 hours.If you have been misusing modafinil as a cognitive enhancer and you want to stop, it's best to do so
gradually to give your body time to adjust to the absence of the medication. Much like other prescription drugs, you should talk to your doctor before modifying your dosage or getting off modafinil entirely.
No interactions were found between Benadryl and modafinil. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider. I ordered modafinil and ambien from
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