For my first cycle I had to decide what was worth stopping my natural test production.. If you use a 250mg per week you are shutting down your natural production same as if you were using a 1000.. So the question is- Is it going to be worth the shut down for the gains you can expect from a 250 mg per week cycle. If so then go for it..
If you start at 250 in 3 weeks you'll be bumping it garunteed. And that is not an issue either. nothing wrong with increasing dose through out a cycle.
Here's the beauty of long esters, for 1 you get more value and your monies worth IMO.. and for two, heavier the ester weight, the longer it will take to cleave the entire hormone ester and metabolize it (finding its way to circulation)..With Cyp or Enath you can achieve a considerable build up of hormone in the blood, yielding a higher serum as time goes on.. Example, it will take quite a few weeks to clear the first injection, yet one will be administering additional injections..say he injects 250mgs, and say 5-7 days later an additional 250mgs, by that time less then half of the first injection has been metabolized and cleared, now we have the NEW build up of the most recent injection/s..Now he takes a 3rd, 4th an a 5th, now we're still working in those first few injections and now all this hormone has built up over time and is ready to reach the blood medium in which can be made bio-available at almost any given moment..We're talking several hundred mgs of hormone here (I don't wish to get into active hormone/molecular weight with short ester vs long ester, this is simply just a brake down for layman's terms)..Before one knows it, they can have a decent amount yielding some respectable TOTAL TEST ng/dl levels..
To the OP, and to answer the question at hand, YES, 250mgs can be more than sufficient for most people, and even used as a maintenance dose for some (for good reason)..
Now, would I use 250mgs starting? That's the million dollar questions... My code of ethics will say "YES"..
Now, my impatient side of me, along with always seeking to maximize results with little effort would say "300-400" could be a better cycle as most people regret not using more for their first time.But you don't really need more that's the magic here..
250 all day long, 300-400 is interesting for a first cycle!
You never know, if you ended up doing this (not knowing any of your stats), you may even end up being a GREAT responder at 250mgs..