From my relatively new personal experience and everything I've read along with talking to others who have used it in the past it seems that 400-600mg a week is the sweet spot as far as maxing your gains etc. I will also say please don't try pushing it to that level when you first try it as it does take some time for your muscles/body to adjust to this compound which is somewhat different than most of the compounds we are all used to.
I would definitely suggest starting it similarly to front loading (which I don't think is a necessary thing in general and doesn't really get you any added benefits). What I mean is pinning eod or even ed (different sites each time and with another compound at first for sure) for the first 1-2 weeks. I pinned 1ml eod so 100mg eod with the tpp/npp/mast p blend to start with no problems and now doing 2ml with that blend eod and haven't experienced any issues. That was 3 weeks of the 1ml DHB with the blend eod and now on week 2 I believe of the 2ml DHB with the blend eod (had to take some time a week off for doctor related issues so times are a little fuzzy/off on this cycle).
Once you have acclimated your body to the compound then the sky is the limit as I know of at least one person that was pushing 1g of it a week with no issues after he had been using it for a while and absolutely loved his results and has told me that he won't hesitate to do so again when he runs another cycle. Life things have kept him from running anything over the last year and he obviously wasn't running anything I made as this is my first go with this stuff just to clarify.
Also, for those of you who have followed my experience with this compound you know that the first batch I made that was a Mig only batch was no bueno and the pip was real lol. I laugh now at it but I sure as hell wasn't laughing then so just be careful when you start and make sure it's a good fit for you as we are all different and in the same way that I can't handle Tren there are probably those that don't do well with this.
Anyway, if y'all have any questions about this stuff please feel free to pm or email me or ldog and we'll do our best to help you in any way that we can.
GC