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AIDS Cured?

tommygunz

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[h=1]A baby now free of HIV has doctors talking about 'cure'[/h]Johns Hopkins Medicine



By Maggie Fox, Senior Writer, NBC News
A baby born infected with the AIDS virus who got immediate treatment now has no detectable virus in her blood – not quite a cure, but so close to one that it has doctors talking about the possibility.
Her case, presented to a meeting of AIDS researchers that started Sunday, will prompt questions about how early babies should be treated – and further illustrates the possibility that immediate treatment with HIV drugs might stop infection in its tracks and could even have an impact on the AIDS pandemic.
“What we have identified is what we think is the first well-documented case of a functional cure in a neonatal child,” Dr. Deborah Persaud of the Johns Hopkins Children’s Center, the virologist who led the study, told NBC News.





A functional cure, says Persaud, means the virus isn’t entirely gone, but it’s not doing any damage, either. Doctors think it was because they began therapy for the baby within 48 hours of being infected, she told a conference in Atlanta of HIV specialists.
The child, who lives in rural Mississippi, is now 2 1/2 and healthy. She was, like so many, born to a mother who didn’t know until right before she gave birth that she had the human immunodeficiency virus (HIV) that causes AIDS. Mom and baby both got a standard dose of HIV drugs right away – something that has been shown to prevent what’s known as mother-to-child transmission of the virus in newborns.
The baby was a little premature and so stayed in the hospital. Within 30 hours of birth she was re-tested and had clear evidence of HIV infection. Unusually, she then got a cocktail of three drugs at a dose normally reserved for more advanced cases. It worked really well – pushing her virus down to what’s called undetectable levels. This is what doctors want with HIV, because if the virus can’t be found in the blood, then it can’t be spreading and damaging the immune system. HIV doesn’t kill directly – it kills patients by damaging their immune systems so bad they can’t fight off other infections.
The baby and her mom, who doctors aren't naming, got regular care and treatment by Dr. Hannah Gay at University of Mississippi Medical Center until she was 15 months old. Then, like so many children, she disappeared off the doctors’ radar screens. The mother brought her back briefly at 18 months but disappeared again but she missed at least eight months worth of drugs. When Gay caught up to her again, the baby was still well, despite having received no treatment. More remarkably, tests showed the virus had not come back.

“My first thought was, ‘oh my goodness. We have been treating an uninfected child,” Gay told NBC News. "But I checked the records which confirmed she was, in fact, infected.
Dr. Katherine Luzuriaga of the University of Massachusetts Medical School, who also worked on the study, piled on with a battery of tests. Even a sensitive test called PCR, which can help find tiny bits of genetic material from a virus, couldn’t detect any evidence of HIV. This went far beyond the usual definition of "undetectable" in treating the AIDS virus - there really was no evidence the virus was there.
“What we did then was to get a group of collaborating laboratories together to apply ultra-sensitive testing and say ‘can we detect any evidence of virus’,” Luzuriaga says. They did eventually find pieces of genetic material from the virus.
But Persaud has been unable to find any evidence of virus that can invade cells or replicate. “So the baby has remained off treatment. We are just watching and we will follow the baby and do additional testing.”
It’s not a true cure – what doctors call a “sterilizing” cure. There is still virus in the toddler’s body. But it’s not is a form that seems to be doing any damage. It doesn’t seem to be able to spread from one cell to another and it doesn’t seem to be damaging the child’s immune system.
About 34 million people globally are infected with HIV, the virus that causes AIDS; 25 million have died from it. While there’s no vaccine, cocktails of powerful antiviral drugs called antiretroviral therapy (ART) can keep the virus suppressed and keep patients healthy. No matter how long patients take ART, however, they are never cured. The virus lurks in the body and comes back if the drugs are stopped. Scientists want to flush out these so-called reservoirs and find a way to kill the virus for good.





“This has major implications for how we begin to think about treating children,” Persaud says. “Perhaps we can spare them a lifetime of treatment.”
But she adds, it’s one case. “We need to figure out if this can be reproduced or replicated in other infants.”
Babies born to HIV-positive women are different from other HIV patients. Doctors know the precise moment that they are infected and can treat them right away. But usually they treat them with low doses of drugs for about six weeks and then wait to see if infection has really developed before they treat them again. If done right, this treatment around birth can prevent 95 percent of infections.
Up to now, only one person has been documented with a cure – the so-called Berlin patient, Timothy Brown, who was treated for leukemia with a bone marrow transplant that happened to come from a donor with a genetic mutation that makes immune cells resist HIV infection. The transplant replaced his own infected cells with healthy, AIDS-resistant cells. He is remains free of the virus more than five years later.
Dr. Dan Kuritzkes of Brigham and Women's Hospital and Harvard Medical School is treating two HIV other patients who, like Brown, got bone marrow transplants for leukemia or lymphoma. His team wants to see if they, too, can be cured. “They are doing fine,” he says – but continue taking HIV drugs to be safe.
But a third patient he was treating suffered a relapse of lymphoma and died. “It sort of underscores what these patients have been through,” he said. No one thinks a bone marrow transplant represents a real-life treatment for anyone with HIV, because it’s so hard on the body.
Kuritzkes said AIDS experts have wondered whether very early treatment of newborns could be in fact treating their infection rather than preventing it.
“It’s exciting because there are undoubtedly other children in this situation,” he said. His team is taking part in several studies looking at whether it is possible to eradicate the reservoirs of virus in adults that should have results within a year.
There are also patients called “elite controllers” who seem to stay well and suppress the virus without the need for drugs.
Luzuriaga says this toddler is not an elite controller. “You can detect HIV DNA in their cells. And you can culture virus from them,” she said. “We just think that this baby has much tighter control, much tighter control. This baby hasn’t rebounded off therapy.”
“Our next step is to find out if this is a highly unusual response to very early antiretroviral therapy or something we can actually replicate in other high-risk newborns,” says Persaud.
It might be that quick treatment stopped the virus from hiding out in the baby’s body, and allowed the drugs to do their work and stop the spread of the virus.
 
Very good news indeed. As a person who has lived with MS for 19 years any news on auto immune diseases is welcome. Not only is it good news for those afflicted with HIV but also all others. The many advancements in the research into my illness can be linked to aids research. It has opened new doors in our understanding of the CNS and that benefits us all.
 
oh just a quick note of caution. Be very very careful of throwing the "cure" word out there. Many have had hope raised very high just to be devastated. Myself included many many years ago as pertains to my own illness.
 
Ok so, thats great and all for kids, but what about the adults who are fucking like rabbits with no condoms? Eventually those kids grow up with no aids, fuck an adult with aids, and get aids. No deal done. Just sayin.

Unless this can lead to a cure for adult aids, its pretty much pointless.
 
You have a point heathalot. However thats not the whole story. For every new revelation or advancement in knowledge its invaluable. Think of knowledge into causes,cures,treatments into diseases being the same as interest in your bank account. It compounds and grows in the same way your money does. Every new discovery unlocks more doors in other directions etc. Besides the more they can slow the proliferation of any disease they quicker they may go the way of polio etc. Its a slow and cautious process but all very worthwhile. Even if most research is funded by big pharma looking for the next cash cow drug its all still worth it.
 
A very smart ma once told me somthing that I will never forget . Hospitals and doctors aren't there to cure you they are there to treat you . There is no money in curing patients . Dont have false hope .
 
I'm not even gonna read the text,treating is a lot more expensive them curing someone, so why the fuck would the health industry want to cure people?
 
I guess that if your theory held water we would still have Smallpox and Polio, but we don't. This is just another step in the direction towards a cure and that is a step in the direction towards inoculation, that is where the money will be. I suppose if your daughter or sister was infected you'd not give two shit who was making a dime. Many people who have been infected with this disease through no fault of their own would not disagree.
 
I guess that if your theory held water we would still have Smallpox and Polio, but we don't. This is just another step in the direction towards a cure and that is a step in the direction towards inoculation, that is where the money will be. I suppose if your daughter or sister was infected you'd not give two shit who was making a dime. Many people who have been infected with this disease through no fault of their own would not disagree.

Tommy I like you and HAD alot of respect for you and the way you carry yourself on here but you are 1000000 % wrong . Small pox and Polio lmfao really??? Pharmaceutical companys DID NOT control the country like they do today 70 years ago .. Today pharmaceutical companys control policy and have every goverment official on the payroll . Cmon TG get with the times bro .This is not 1945 . Inoculation LMFAO again ! Yea Im sure pharmaceutical companys are just chopping at the bit to come up with cures so they can make a 1 time fee instead of charging fees for the rest of the patients life . I suggest you rethink your position and put a lil more thought into your opinions . And by the way my Mother is HIV positive and has been for the last 18 years , so tell me again how much I dont care . Yea maybe your right . I guess the big pharmas would have rather seeen my mother cured 18 years ago instead of banging the system out for every dollar they can for the last 18 years . I thought you were a smart guy , Guess I was wrong . Really bro ???? Polio and small pox lmfao again ? THERE IS NO MONEY IN CURES ONLY IN TREATMENTS .

Tell me again how I dont care ....Dude you really dont know much about anything except giving reviews on gear . I suggest you stick to that
 
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It's just a news story and a little positive hope for a lot of people. I'm not sure why you got your self so wound up bro. This is a general discussion thread, adhere to some decorum or leave.
 
IML Gear Cream!
I thought aids was a myth it was supposedly out of control in the 80's and 90's. This is the first article I have read in a long time. So bad news there really is aids good news they are getting closer to a cure.
 
I wonder how much Magic Johnson has spent on "treatment." He's been HIV positive for what seems like 20 years. I heard he's in remission but not cured. Still has to take a bunch of pills everyday.
 
how is this anything new? there are plenty of people who take their cocktails and at some point the levels of the HIV virus become so low they are practically undetectable. eg. Magic Johnson
 
There is a popular misconception that is misguidedly repeated that goes something like this: "They haven't cured a disease since polio." In 1955, Jonas Salk M.D. developed a preventative vaccine for polio (the same idea behind the influenza vaccine). Polio was never cured. It was systematically and widely prevented. Since polio doesn't mutate on the level that influenza does, we see cases of the flu and only rarely - if ever - see cases of polio.

Typically, people will use this misconception to illustrate that, indeed, it is possible to cure a disease, but doctors don't do it now because there is a world wide conspiracy to make money off of the sick. Somehow, we are to swallow this idea that even with global communication connecting everyone to everyone else and the fact that there are doctors all over the world with perfectly healthy consciences who have retired from the profession casting away their former allegiances, that the conspiracy is so airtight, no one would let out the secret formulas to the health of the world. Somehow, we are to believe that everyone in the health care profession is under strict orders from the legal system in every country in the world to keep the population sick.

Do pharmaceutical companies take advantage of people? There is strong evidence to support that they do. Are people in the medical research profession looking for ways to cure people? There is strong evidence to support that they are. You can bet that if humans have problems, scientists are looking for a way to solve it, not for the sake of money, but for the sake of science.

But let's make the assumption that it IS for the sake of money. It is important to take into account that it is a cure that will make much more money for a research team than any symptom suppressant or vaccine. Pharmaceutical companies are in competition with each other. By the logic of those who would have us believe that the almighty dollar is the reason that these companies don't research for cures, we would also have to believe that these companies would rather out compete each other. Why would a corporation settle for sharing the wealth when they could take the full 100%? These companies are hasty and greedy, but they're not stupid.

But still, one could make the case that once the world is rid of the disease, the company's revenues will deplete to a staggering zero. Here we are left to believe that the wonder cure and its associated disease was the only thing that the company had keeping it financially afloat (It isn't: Companies usually supply more than just one drug for one sickness); the pharmaceutical company would not simply develop another symptom suppressant for something else (of course, it would); and of course there must be a world wide shortage of diseases for companies to treat (...there aren't). The pharmaceutical company would still make more money finding and distributing a cure, giving it the corner on the market for long time until it would have to return to 'business as usual'.

Another important point to make is that this assumes that the cure is also somehow a preventative measure distributed to everyone: That not only the sick will be cured but that those who are not sick will not ever get sick. A cure is given to people that are sick with the disease. A preventative measure is something you take to avoid the disease (a vaccine). A cure would make a company money as long as a preventative measure were not discovered, since people would still be getting the disease. By the 'almighty dollar' logic, there should be loads of cures and no vaccines. But there are many preventative measures and few cures. It seems to me that there's every reason that business people would want to find a cure.
 
[h=1]HPV vaccine[/h]From Wikipedia, the free encyclopedia


Vaccine description
Target diseasehuman papillomavirus
TypeProtein subunit
Clinical data
Pregnancy cat.B (US)
Legal status℞-only (US)
Routesinjection
Identifiers
ATC codeJ07BM01 J07BM02
14px-X_mark.svg.png
(what is this?) (verify)

HPV vaccine
The human papilloma virus (HPV) vaccine prevents infection with certain species of human papillomavirus associated with the development ofcervical cancer, genital warts, and some less common cancers.[SUP][1][/SUP][SUP][2][/SUP][SUP][3][/SUP] Two HPV vaccines are currently on the market: Gardasil and Cervarix.[SUP][4][/SUP]
Both vaccines protect against the two HPV types (HPV-16 and HPV-18) that cause 70% of cervical cancers, 80% of anal cancers, 60% of vaginal cancers, and 40% of vulvar cancers.[SUP][5][/SUP] These HPV types also cause most HPV induced oral cancers, and some other rare genital cancers. Gardasil also protects against the two HPV types (HPV-6 and HPV-11) that cause 90% of genital warts.[SUP][2][/SUP]
Both vaccines have been shown to prevent potentially precancerous lesions of the cervix. Gardasil has been shown to prevent potential precursors toanal,[SUP][6][/SUP][SUP][7][/SUP] vulvar,[SUP][8][/SUP] vaginal,[SUP][8][/SUP] and penile[SUP][6][/SUP] cancers. HPV vaccines are expected to protect against HPV induced cancers of these areas as well asHPV induced oral cancers.[SUP][9][/SUP]
The World Health Organization (WHO),[SUP][10][/SUP] as well as public health officials in Australia, Canada, Europe, and the United States recommend vaccination of young women against HPV to prevent cervical cancer, and to reduce the number of treatments for cervical cancer precursors.[SUP][11][/SUP]
Worldwide, HPV is the most common sexually transmitted infection in adults.[SUP][3][/SUP] For example, more than 80% of American women will have contracted at least one strain of HPV by age fifty.[SUP][12][/SUP][SUP][13][/SUP][SUP][14][/SUP][SUP][15][/SUP]
Although most women infected with genital HPV will not have complications from the virus,[SUP][16][/SUP] worldwide there are an estimated 529,000 new cases of cervical cancer and 275,000 deaths per year.[SUP][10][/SUP] About 85 percent of cancers,[SUP][10][/SUP] and eighty percent of deaths from cervical cancer occur in developing countries.[SUP][17][/SUP] In the United States, most of the approximately 11,000 cervical cancers found annually[SUP][18][/SUP] occur in women who have never had a Pap smear, or not had one in the previous five years. HPV is also the cause of cervical intraepithelial neoplasia (CIN).[SUP][19][/SUP] CIN is a precursor to cervical cancer, and is painful and costly to treat.[SUP][20][/SUP] It is not known how many women worldwide are diagnosed with CIN.[SUP][21][/SUP]
Since the vaccine only covers some high-risk types of HPV, experts still recommend that women get regular Pap smear screening even after vaccination.[SUP][22][/SUP]
HPV vaccination is approved for use in males in many areas. In addition to protecting their partners from cervical cancer, vaccination can protect males against anal cancer, and may prevent other HPV associated cancers. Gardasil can also protect males against genital warts. HPV vaccination has been recommended for males in the United States, where vaccine uptake among women has been low. Vaccination is also recommended in populations at higher risk for HPV associated cancers, such as men who have sex with men and those with compromised immune response.
 
Small pox and Polio lmfao really??? Pharmaceutical companys DID NOT control the country like they do today 70 years ago .. This is not 1945 . Inoculation LMFAO again ! I suggest you rethink your position and put a lil more thought into your opinions . And by the way my Mother is HIV positive and has been for the last 18 years , so tell me again how much I dont care . Yea maybe your right . I guess the big pharmas would have rather seeen my mother cured 18 years ago instead of banging the system out for every dollar they can for the last 18 years . Polio and small pox lmfao again ? THERE IS NO MONEY IN CURES ONLY IN TREATMENTS .

Tell me again how I dont care ....Dude you really dont know much about anything

The first vaccine for Polio was introduced in 1950 and followed by the oral vaccine in 1961, Polio cases have decreased globally by 99% since 1988. The last known case of Smallpox was reported in Somalia in 1977 and the World Health Organization declared this globally eradicated in 1979. Until then this was one of the worlds most feared diseases. This is not 70 year old history it is in your and my life span and had it not been for innoculations, treatments and drugs developed by pharmacuetical companies this would be a threat to us now. Murf I think the facts speak for themselves here.



[h=2]HIV IN THE UNITED STATES*[/h][h=3]FAST FACTS[/h]
  • More than one million people are living with HIV in the U.S.
  • One in five living with HIV is unaware of their infection.
  • MSM, particularly young, black MSM, are the most severely affected by HIV.
  • By race, African Americans face the most severe HIV burden.

The first cases of what would later become known as AIDS were reported in the United States in June of 1981. Since then, 1.7 million people in the U.S. are estimated to have been infected with HIV, including over 619,000 who have already died and approximately 1.2 million (1,178,350) adults and adolescents who were living with HIV infection at the end of 2008, the most recent year for which national prevalence estimates are available. The impact of the HIV/AIDS epidemic spans the nation with HIV diagnoses having been reported in all 50 states, the District of Columbia, and the U.S. dependencies, possessions, and associated nations.
CDC estimates that more than one million people are living with HIV in the U.S.. One in five (20%) of those people living with HIV is unaware of their infection.
Despite increases in the total number of people living with HIV in the U.S. in recent years, the annual number of new HIV infections has remained relatively stable. However, new infections continue at far too high a level, with approximately 50,000 Americans becoming infected with HIV each year.
More than 17,000 people with AIDS in the U.S. died in 2009 and more than 619,000 people with AIDS in the U.S. have died since the epidemic began. Gay, bisexual, and other men who have sex with men (MSM)[SUP]1[/SUP] are strongly affected and represent the majority of persons who have died.






In my opinion this is the most threatening disease today, our modern day Smallpox if you will. I agree that there is a huge amount of money involved with big pharma and they exercise too much influence on the governments of the world, this is undeniable. The OP was about the treatment of AIDS in a child being so effective that the disease was no longer detectable. Is that not possibly a cure? Why does how we get there matter as long as we do? Do you think the parents of that child care?

Brother I think this has personal meaning to you and I feel for your mom as I do for the other countlessly innocent victims of this horrible disease. I can understand your slanted opinion and have to respect it, regardless of my disagreement with it. I only hope that medicine can cure/treat this out of existance in hers, yours and my grand childrens lifetimes.
 
I can go post a bunch of facts myself that totally and completely differ from your facts but I dont know how to put links and all that shit . As far as you telling me to leave > NO ! You leave !!!!! and as far as my slanted opinion you are incorrect again !!!! Its not my opinion that pharmas control everything including the goverment !!!!IT is fact !!!!
As far as your last sentence goes > Yes I hope along with you that a cure will be found and giving to everybody !!! I just know IT WONT BE GIVING TO EVERYBODY. Stick to reviews on gear bro its what you do best . I dont dislike you I just think you are like millions of other people in this world > Ignorant . And for future reference dont assume people dont care about something cause you disagree > It makes you look like an asshole . You know the old saying right Assume = Asshole . I believe you are a good guy just believing in something that will never ever happen .. How can you honestly believe that a cure for aids ,cancer or anything else for that matter is in the future ...DO YOU KNOW HOW MUCH OF THIS COUNTRIES ECONOMY DEPENDS ON TREATMENT ???? ARE YOU THAT IGNORANT THAT YOU DONT KNOW WHAT WILL HAPPEN IF A CURE IS EVER FOUND AND GIVEN OUT . You seem to be good at googling things then reposting them . Try finding out how many ppl would lose there livelyhoods if a cure for aids is found . Its the same with cancer . How many people would lose there jobs if a cure for cancer were to be found . SEARCH AND REPOST THAT
 
***** Thank you for not fueling the fire . Whichever way your post was gonna go I feel the same way right about now .I am goin to follow your lead and take myself out of this argument. Its an emotional issue and we all have strong feelings 1 way or the other . my last word on this touchy subject will be a quote from another smart guy " I only hope that medicine can cure/treat this out of existence in hers ,yours ,mine and our grandchildrens lifetime " TG
 
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Murf it's all good, you have to respect a man who stands behind his beliefs. It's not an argument from my stand point, we are debating. No one need go anywhere, I purposely started this thread to stimulate conversation. It's good to get this out in the open.
 
A cure for HIV/AIDS.... not to sure about this as of yet.. The real test will be down the road in about 6 months to a year with out the meds. Should be interesting to see the results
 
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