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Though its not perfect, this will try to answer questions regarding gyno prevention and reversal,
the use of Letrozole and other anti-E’s. I will go over
everything in very simple easy to understand language. Also we are talking about
estrogen gyno here, not progesterone (but using letro will stop
progesterone related problems as well since it inhibits all estrogen
anyways). Progesterone gyno will be enlargement of your nipple
area, the actual aereola, not a lump under it.
Let me make this first
point very clear, as I state in my signature this is from my personal
experience, so whether you agree with it or not is your own issue. I have helped
many people with gyno and it has worked just fine for them as
well.
To first understand why you are doing what you are doing I am going
to go over a few things and a few definitions:
SERM – Selective
estrogen Receptor Modulator. These drugs work by binding to the
estrogen receptors and flooding them in a sense, making it
difficult (but not impossible by any means) for estrogen to bind
to the receptors and thus prevent the onset of estrogen related
side effects.
Most common forms: Tamoxifen (Nolvadex), Clomiphene
(clomid)
AI – Aromatise Inhibitor. These drugs work by inhibiting the
aromatization of estrogen. This means that in effect AI’s prevent
androgens from converting to estrogen, again, making it difficult (but
not impossible) for estrogen to reach receptor sites.
Most
common forms: Anastrozole (l-dex, a-dex), Exemestane
(Aromasin), FEMARA (Letrozole). For our purpose of reversing
gyno we are interested in Letro.
Letro and your sex
drive:
Letrozole will suppress your sex drive. This is another reason
why it is so important to act on preventing gyno as soon as possible.
Since we all know that Test should be run in every cycle this will cancel
out the effect of sex drive suppression.
Running letro to prevent
gyno:
If you decide to run estrogen protection while on
cycle (and I suggest you do unless you are aware that you do not require
it), you can run either a SERM or an AI. Letro will be the most powerful
AI you can use, it will inhibit 98+% of estrogen using a dose as
low as .25mg and even lower. This is why I suggest you do not use a dose higher
than .50mg while on cycle just trying to prevent estrogen
related side effects.
You will want to start running the letro
approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don’t know if I buy into this for the reason that I have reversed gyno after using letro for only 1 week. Still to be safe I
recommend starting it before your cycle as stated above.
If you do
decide to run letro there is absolutely no need to run another AI or
SERM. Do not make the mistake of thinking more is better. Think of it
this way; if letro is preventing the conversion of androgens to estrogen
than there is no estrogen, what would the purpose of a
SERM be when there is no estrogen to bind to the receptors?
Nolva will only take away from the effectiveness of letro.
This brings me
to my next point. Do not listen to anyone who tells you to bump up your
Nolvadex to 60+mg ED if you get gyno. I have no idea where this
idea started but I have seen it suggest far too many times recently.
Nolvadex will do nothing to reverse your gyno…let me make that
clear IT WILL DO NOTHING FOR gyno. If you are running nolva as your
anti-E and start to develop gyno than sure you can bump the
dosage a small amount to try to prevent it from progressing further, but
Letrozole must begin ASAP.
It is very important that you begin
taking Letrozole immediately, the longer your wait the more risk you take
in not being able to reverse it.
How do I know if I have
gyno?
If you have developed gyno you will have a lump behind
your nipple. It will be fairly hard, and it will be tender to
touch.
Running letro to reverse gyno:
I am going to go over the
three different scenarios which people could fit into. Remember regardless of
what scenario you are in it is important that you begin taking the letro
ASAP.
1. Already using an anti-E aside from letro.
2.
Already using letro @ a dose of .25mg or .50mg ED.
3. Not running any
estrogen protection.
1.
Day 1: .25mg Letro +
anti-E*
Day 2: .50mg Letro
Day 3: 1.0mg Letro
Day 4:
1.5mg Letro
Day 5: 2.0mg Letro
Day 6: 2.5mg Letro **
2.
Day 1:
.50mg Letro
Day 2: 1.0mg Letro
Day 3: 1.5mg Letro
Day 4: 2.0mg
Letro
Day 5: 2.5mg Letro **
3.
Day 1: .50mg Letro
Day 2: 1.0mg
Letro
Day 3: 1.5mg Letro
Day 4: 2.0mg Letro
Day 5: 2.5mg Letro
**
*Regardless of the anti-E you are using it is important
to still use it for the first day you begin letro as the letro will not have
taken any effect and you by no means want your body to be without any protection
when gyno is already prevalent.
** You will remain at this dose
until gyno symptoms subside. Once you believe your gyno is gone it
is important to stay at this dose for another 4-7 days to ensure all traces are
gone. I recommend people with a bf% over 15 stay on for a week as it may be
harder to judge completely whether the lump is completely gone. Once this period
is over it will be important to taper letro down slowly rather than coming off
it completely. Regardless of which manner you tapered up your dose you will all
taper down in the same fashion.
Day 1: 2.0mg
Day 2: 1.5mg
Day 3:
1.0mg
Day 4: .50mg***
Day 5: .25mg
***You can remain at this dose or go
down further to .25mg. It is really up to you at this point. They are both very
common maintenance doses as an anti-E while on cycle.
Personally I have stayed with .25mg and never had a problem.
Letro and
the estrogen rebound:
With your estrogen being
completely inhibited there is a definite estrogen rebound as your
body tries to re-stabilize the testosterone :estrogen
balance. We can prevent this rebound effect by supplementing further
with another AI or SERM. So, I suggest that when you are coming to the
end of your cycle you will more than likely be using Nolva in your
PCT so just make sure that you begin taking nolva the last day you are
going to take your letro and then continue on as you would with regular
PCT.
This now leads us into the question of reversing gyno
while not on cycle. There are a few things to remember here. You have
already waited longer than you should have, and your sex drive will be shot. You
can use tribulus or another natural test booster to help you in this scenario
but I can’t guarantee the effectiveness. Just follow gyno reversal
protocols 2 or 3. When coming off again you must taper and begin using
Nolvadex to prevent any rebound effect that may occur.
How much
Nolvadex should you use if you are not going into PCT and running
this off cycle? I suggest starting at 20mg ED for a week and then
lowering it to 10mg for another week and then coming off completely.
Though its not perfect, this will try to answer questions regarding gyno prevention and reversal,
the use of Letrozole and other anti-E’s. I will go over
everything in very simple easy to understand language. Also we are talking about
estrogen gyno here, not progesterone (but using letro will stop
progesterone related problems as well since it inhibits all estrogen
anyways). Progesterone gyno will be enlargement of your nipple
area, the actual aereola, not a lump under it.
Let me make this first
point very clear, as I state in my signature this is from my personal
experience, so whether you agree with it or not is your own issue. I have helped
many people with gyno and it has worked just fine for them as
well.
To first understand why you are doing what you are doing I am going
to go over a few things and a few definitions:
SERM – Selective
estrogen Receptor Modulator. These drugs work by binding to the
estrogen receptors and flooding them in a sense, making it
difficult (but not impossible by any means) for estrogen to bind
to the receptors and thus prevent the onset of estrogen related
side effects.
Most common forms: Tamoxifen (Nolvadex), Clomiphene
(clomid)
AI – Aromatise Inhibitor. These drugs work by inhibiting the
aromatization of estrogen. This means that in effect AI’s prevent
androgens from converting to estrogen, again, making it difficult (but
not impossible) for estrogen to reach receptor sites.
Most
common forms: Anastrozole (l-dex, a-dex), Exemestane
(Aromasin), FEMARA (Letrozole). For our purpose of reversing
gyno we are interested in Letro.
Letro and your sex
drive:
Letrozole will suppress your sex drive. This is another reason
why it is so important to act on preventing gyno as soon as possible.
Since we all know that Test should be run in every cycle this will cancel
out the effect of sex drive suppression.
Running letro to prevent
gyno:
If you decide to run estrogen protection while on
cycle (and I suggest you do unless you are aware that you do not require
it), you can run either a SERM or an AI. Letro will be the most powerful
AI you can use, it will inhibit 98+% of estrogen using a dose as
low as .25mg and even lower. This is why I suggest you do not use a dose higher
than .50mg while on cycle just trying to prevent estrogen
related side effects.
You will want to start running the letro
approximately 2 weeks before you begin your cycle to allow it to fully stabilize in your blood. I have often heard the argument that letro takes up to 60 days to stabilize, I don’t know if I buy into this for the reason that I have reversed gyno after using letro for only 1 week. Still to be safe I
recommend starting it before your cycle as stated above.
If you do
decide to run letro there is absolutely no need to run another AI or
SERM. Do not make the mistake of thinking more is better. Think of it
this way; if letro is preventing the conversion of androgens to estrogen
than there is no estrogen, what would the purpose of a
SERM be when there is no estrogen to bind to the receptors?
Nolva will only take away from the effectiveness of letro.
This brings me
to my next point. Do not listen to anyone who tells you to bump up your
Nolvadex to 60+mg ED if you get gyno. I have no idea where this
idea started but I have seen it suggest far too many times recently.
Nolvadex will do nothing to reverse your gyno…let me make that
clear IT WILL DO NOTHING FOR gyno. If you are running nolva as your
anti-E and start to develop gyno than sure you can bump the
dosage a small amount to try to prevent it from progressing further, but
Letrozole must begin ASAP.
It is very important that you begin
taking Letrozole immediately, the longer your wait the more risk you take
in not being able to reverse it.
How do I know if I have
gyno?
If you have developed gyno you will have a lump behind
your nipple. It will be fairly hard, and it will be tender to
touch.
Running letro to reverse gyno:
I am going to go over the
three different scenarios which people could fit into. Remember regardless of
what scenario you are in it is important that you begin taking the letro
ASAP.
1. Already using an anti-E aside from letro.
2.
Already using letro @ a dose of .25mg or .50mg ED.
3. Not running any
estrogen protection.
1.
Day 1: .25mg Letro +
anti-E*
Day 2: .50mg Letro
Day 3: 1.0mg Letro
Day 4:
1.5mg Letro
Day 5: 2.0mg Letro
Day 6: 2.5mg Letro **
2.
Day 1:
.50mg Letro
Day 2: 1.0mg Letro
Day 3: 1.5mg Letro
Day 4: 2.0mg
Letro
Day 5: 2.5mg Letro **
3.
Day 1: .50mg Letro
Day 2: 1.0mg
Letro
Day 3: 1.5mg Letro
Day 4: 2.0mg Letro
Day 5: 2.5mg Letro
**
*Regardless of the anti-E you are using it is important
to still use it for the first day you begin letro as the letro will not have
taken any effect and you by no means want your body to be without any protection
when gyno is already prevalent.
** You will remain at this dose
until gyno symptoms subside. Once you believe your gyno is gone it
is important to stay at this dose for another 4-7 days to ensure all traces are
gone. I recommend people with a bf% over 15 stay on for a week as it may be
harder to judge completely whether the lump is completely gone. Once this period
is over it will be important to taper letro down slowly rather than coming off
it completely. Regardless of which manner you tapered up your dose you will all
taper down in the same fashion.
Day 1: 2.0mg
Day 2: 1.5mg
Day 3:
1.0mg
Day 4: .50mg***
Day 5: .25mg
***You can remain at this dose or go
down further to .25mg. It is really up to you at this point. They are both very
common maintenance doses as an anti-E while on cycle.
Personally I have stayed with .25mg and never had a problem.
Letro and
the estrogen rebound:
With your estrogen being
completely inhibited there is a definite estrogen rebound as your
body tries to re-stabilize the testosterone :estrogen
balance. We can prevent this rebound effect by supplementing further
with another AI or SERM. So, I suggest that when you are coming to the
end of your cycle you will more than likely be using Nolva in your
PCT so just make sure that you begin taking nolva the last day you are
going to take your letro and then continue on as you would with regular
PCT.
This now leads us into the question of reversing gyno
while not on cycle. There are a few things to remember here. You have
already waited longer than you should have, and your sex drive will be shot. You
can use tribulus or another natural test booster to help you in this scenario
but I can’t guarantee the effectiveness. Just follow gyno reversal
protocols 2 or 3. When coming off again you must taper and begin using
Nolvadex to prevent any rebound effect that may occur.
How much
Nolvadex should you use if you are not going into PCT and running
this off cycle? I suggest starting at 20mg ED for a week and then
lowering it to 10mg for another week and then coming off completely.
