Hepatotoxicity maybe a little exaggerated??

So is it possible maybe thinking the old liver can't handle a 40mg dbol run without support a little archaic? I don't know. Some of you more intellectual types get in on this. Granted its just one study and I haven't looked at any others cause I'm working.


Anabolic steroid-induced hepatotoxicity: is it overstated?

Dickerman RD, Pertusi RM, Zachariah NY, Dufour DR, McConathy WJ.
Source The Department of Biomedical Science, University of North Texas Health Science Center, Fort Worth 76107-2699, USA.

Abstract

OBJECTIVE:

There have been numerous reports of hepatic dysfunction secondary to anabolic steroid use based on elevated levels of serum aminotransferases. This study was conducted to distinguish between serum aminotransaminase elevations secondary to intense resistance training and anabolic steroid-induced hepatotoxicity in elite bodybuilders.
DESIGN:

This was a case-control study of serum chemistry profiles from bodybuilders using and not using anabolic steroids with comparisons to a cohort of medical students and patients with hepatitis.
PARTICIPANTS:

The participants were bodybuilders taking self-directed regimens of anabolic steroids (n = 15) and bodybuilders not taking steroids (n = 10). Blood chemistry profiles from patients with viral hepatitis (n = 49) and exercising and nonexercising medical students (592) were used as controls.
MAIN OUTCOME MEASURES:

The focus in blood chemistry profiles was aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltranspeptidase (GGT), and creatine kinase (CK) levels.
RESULTS:

In both groups of bodybuilders, CK, AST, and ALT were elevated, whereas GGT remained in the normal range. In contrast, patients with hepatitis had elevations of all three enzymes: ALT, AST, and GGT. Creatine kinase (CK) was elevated in all exercising groups. Patients with hepatitis were the only group in which a correlation was found between aminotransferases and GGT.
CONCLUSION:

Prior reports of anabolic steroid-induced hepatotoxicity based on elevated aminotransferase levels may have been overstated, because no exercising subjects, including steroid users, demonstrated hepatic dysfunction based on GGT levels. Such reports may have misled the medical community to emphasize steroid-induced hepatotoxicity when interpreting elevated aminotransferase levels and disregard muscle damage. For these reasons, when evaluating hepatic function in cases of anabolic steroid therapy or abuse, CK and GGT levels should be considered in addition to ALT and AST levels as essential elements of the assessment.

Unfortunately the article doesn't show what they were taking. It actually say it was all "self-medicated" use. So who really know what they were taking. That being said a bottle of Liv-52 and bottle of NAC wouldn't run you more than $30 maximum. Better safe than sorry right? Drink lots of water, eat fiber, take NAC and Liv-52. I think the damage steroids create to the liver aren't,"Do one cycle and enzymes are "slightly" elevated." But more so over a period of say 10 years.

My question is, if alcohol is worse on the liver??? I don't know.

I would play it safe though. NAC and Liv-52 are cheap. Many people stand behind them.

That's how I came across that study. Trying to find a good source for the India liv-52 not the American shit. Where's a good spot to get it from unexpired??

Boom (take as directed)
http://www.vitaminshoppe.com/p/hima...ian-capsules/h0-1002&activateTab=reviews#tabs
and BOOM! 1200MG a day
http://www.vitaminshoppe.com/p/nac-acetyl-l-cysteine-600-mg-100-capsules/vs-1295#.U0cQxPldU1Y


Now the first link of for LiverCare the American version of Liv-52. I never heard anything about it being less effective though. Never tried liv-52/livercare either though.

KCBARBELLJOE said:

Unfortunately the article doesn't show what they were taking. It actually say it was all "self-medicated" use. So who really know what they were taking. That being said a bottle of Liv-52 and bottle of NAC wouldn't run you more than $30 maximum. Better safe than sorry right? Drink lots of water, eat fiber, take NAC and Liv-52. I think the damage steroids create to the liver aren't,"Do one cycle and enzymes are "slightly" elevated." But more so over a period of say 10 years.

My question is, if alcohol is worse on the liver??? I don't know.



I would play it safe though. NAC and Liv-52 are cheap. Many people stand behind them.

Click to expand...

Bros just wanted to chime in. Surprisingly the liver is one organ within the human body that has the ability to regenerate it's cells. Alcohol consumption over an extended amount of time for many years can do permanent damage to the liver. My advice falls right in line with my bro KC. NAC & LIV-52... I would also say have a solid nutrition plan, your diet needs to be sound and concise. Many people have a condition known as fatty liver disease primarily due to their diet and they aren't even aware of it. FLD can indeed also affect the functioning of the liver as well.