I have lupus, so fatigue is something I suffer from more than any other side from the disease. I've been like this for many years and decided to go get checked around the time I was deciding on trt so I had my dr do a full panel to check for anything and everything he can through blood. I came back positive on 3 different labs for lupus. Other than fatigue and always wanting to sleep it doesn't really bother me. My joints get achy from time to time but it could be worse. Some people aren't able to do shit and have to quit working and functioning like a regular person because of it. So I'm pretty lucky. I had no idea what the hell lupus was until I found out I had it. I'll tell you what though, it makes it nice while on tren. I sleep so good and don't suffer from night sweats. All I have to do is lay down and close my eyes and I'll be out within a minute or 2 and can sleep for a few hours.